Microfluidic Strategy For Circulating Tumour Cells Analysis In Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$429,180.00
Summary
My approach and ultimate goal over the next 4 years is to demonstrate the use of recently discovered “Nanoshearing” technology as a standard diagnostic tool for cancer patients undergoing systemic therapy and assess the impact of standard protocols in predicting response to therapy and patient outcomes. Data from this study could potentially define new standards of clinical practice, as they relate to follow-up screening for response to therapy and recurrence of disease.
Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the fin ....Developmental Pathways to Intimate Partner Homicide: Understanding Individual and Situational Dimensions. Intimate partner homicide is a serious public health and safety issue. This project will have several benefits. The findings will extend understanding of pathways leading to partner homicide. The findings will contribute to improved decision-making models by police and social welfare agencies. With more valid information about the changing characteristics leading to partner homicide, the findings will foster more effective and efficient responses. Additionally, the findings will inform victims of partner violence of risks related to escalation toward fatal outcomes and should facilitate help seeking behaviour. Collectively, project findings should expand understanding, improve service delivery and save lives.
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Understanding and Costing Offending Trajectories: Creating an Evidence-Base for Targeting Crime Prevention. The research will provide an evidence-base for targeting diversionary and crime prevention programs and for assessing their cost-effectiveness. Many of these programs have resulted in a range of beneficial outcomes and they are receiving increased government funding. By providing a better understanding of offending pathways, the research will enable programs to be targeted towards particul ....Understanding and Costing Offending Trajectories: Creating an Evidence-Base for Targeting Crime Prevention. The research will provide an evidence-base for targeting diversionary and crime prevention programs and for assessing their cost-effectiveness. Many of these programs have resulted in a range of beneficial outcomes and they are receiving increased government funding. By providing a better understanding of offending pathways, the research will enable programs to be targeted towards particular at-risk groups at crucial developmental phases. The innovative longitudinal costing method that will be developed and applied in the Queensland context will enable an assessment of the cost-effectiveness of diversionary and crime prevention programs. This will provide a sound empirical basis for directing scarce government resources.Read moreRead less
The Effectiveness Of An Indicated Prevention Program For Anxiety
Funder
National Health and Medical Research Council
Funding Amount
$867,982.00
Summary
Generalised anxiety disorder (GAD) is a common disorder. In this research project, we evaluate the effectiveness of a new automated Internet program which is designed to reduce the risk of GAD and to promote self help. If found to be effective, this website will provide assistance to those at risk living in rural and remote areas without access to other resources, and individuals who prefer to seek help anonymously.
Whistling While They Work: Enhancing the Theory and Practice of Internal Witness Management in Public Sector Organisations. The protection of whistleblowers and other internal witnesses to corruption, misconduct and maladministration is a great unsolved problem in public sector governance. Involving 11 integrity institutions, this first national study of internal witness management will describe and compare organisational experience under varying public interest disclosure regimes across the Au ....Whistling While They Work: Enhancing the Theory and Practice of Internal Witness Management in Public Sector Organisations. The protection of whistleblowers and other internal witnesses to corruption, misconduct and maladministration is a great unsolved problem in public sector governance. Involving 11 integrity institutions, this first national study of internal witness management will describe and compare organisational experience under varying public interest disclosure regimes across the Australian public sector. By identifying and promoting current best practice in workplace responses to public interest whistleblowing, the project will use the experience and perceptions of internal witnesses and first- and second-level managers to identify more routine strategies for preventing, reducing and addressing reprisals and other whistleblowing-related conflicts.Read moreRead less
DNA FINGERPRINTING IN DOCUMENT SECURITY TO COUNTER TERRORISM. Crime costs Australia >$18 billion per year. Of this, money laundering/document fraud is estimated at ~$4.5 billion and ~$1.5 to $3 trillion worldwide. Although many techniques combat document fraud (signatures, specialised inks and paper, watermarking etc) they are severely limited by low specificity or are easy to copy.
Alternatively identification by DNA fingerprinting is highly specific (>10 billion to 1) and can now be obtain ....DNA FINGERPRINTING IN DOCUMENT SECURITY TO COUNTER TERRORISM. Crime costs Australia >$18 billion per year. Of this, money laundering/document fraud is estimated at ~$4.5 billion and ~$1.5 to $3 trillion worldwide. Although many techniques combat document fraud (signatures, specialised inks and paper, watermarking etc) they are severely limited by low specificity or are easy to copy.
Alternatively identification by DNA fingerprinting is highly specific (>10 billion to 1) and can now be obtained from cells embedded within paper. This project will use these techniques to provide definitive document validity and authenticity to minimise document fraud and thus counter illicit finance and terrorist funding.
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Crime and CCTV in Australia: Understanding the Relationship. Crime costs Australia $32 billion annually (Mayhew, 2003). Increased criminal and terrorist activities, internationally and nationally have caused major breaches of security in public places, resulting in heightened investment in crime prevention strategies including Closed Circuit Television (CCTV). However, rigorous research into CCTV's effectiveness on crimes in public places has not been undertaken. This innovative project will ide ....Crime and CCTV in Australia: Understanding the Relationship. Crime costs Australia $32 billion annually (Mayhew, 2003). Increased criminal and terrorist activities, internationally and nationally have caused major breaches of security in public places, resulting in heightened investment in crime prevention strategies including Closed Circuit Television (CCTV). However, rigorous research into CCTV's effectiveness on crimes in public places has not been undertaken. This innovative project will identify CCTV's impact on crime and key socio-legal issues of security of public places. The outcomes will contribute to an important decision-making model for local, state, and federal departments, and private sector organisations responsible for CCTV and related crime prevention technologies. Read moreRead less
Preventing Early Internalising Problems In The Preschool Setting: Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$893,870.00
Summary
Internalising mental health problems reflect inner emotional distress and encompass all symptoms of anxiety and depression. Affecting 1 in 7 Australian school-age children, many internalising problems persist into adulthood, impacting on personal wellbeing, family relations and workforce capabilities. This randomised prevention trial in the preschool-setting, screens for children at-risk and tests if a parenting program can reduce internalising problems across the population by school-entry.