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Development Of A Magnetic Resonance Imaging (MRI) Platform To Evaluate Neuroprotective And Regenerative Therapies In MS
Funder
National Health and Medical Research Council
Funding Amount
$116,667.00
Summary
Multiple Sclerosis (MS) involves inflammation and damage to nerve cells. New therapies are needed to minimize and reverse nerve cell damage. Currently, ways to judge the benefit of these therapies are primitive. We propose that assessing the benefits of these treatments in optic neuritis (inflammation of the eye nerve) is the way forward but first, we need to develop reliable tests to measure these treatments. This application proposes to use magnetic resonance imaging (MRI) for this purpose.
Cognitive Dysfunction In Multiple Sclerosis And Its Relationship To Mood Disturbance And Fatigue
Funder
National Health and Medical Research Council
Funding Amount
$57,342.00
Summary
This research aims to test a hypothesized model addressing the interplay between cognitive dysfunction, mood disturbance, and fatigue in people with multiple sclerosis as well as determine the associated impact on daily functioning and quality of life. The importance of background factors, disease factors and psychosocial factors in predicting cognitive dysfunction will also be investigated. Recommendations for new rehabilitation approaches will be developed in light of our findings.