Supporting adaptive diagrammatic communication. The computing environment of the near future will allow users to access and
interact with digital information using an incredible variety of devices.
Regardless of these changes, humans will still be communicating using
diagrams and sketches. But unlike today where diagrams are static,
lifeless objects reflecting their origin in print media, the computer of
the near future will provide more flexible visual computer interfaces which
support ....Supporting adaptive diagrammatic communication. The computing environment of the near future will allow users to access and
interact with digital information using an incredible variety of devices.
Regardless of these changes, humans will still be communicating using
diagrams and sketches. But unlike today where diagrams are static,
lifeless objects reflecting their origin in print media, the computer of
the near future will provide more flexible visual computer interfaces which
support adaptive layout, user interaction and semantics based retrieval.
Based on geometric constraint solving, this project will provide a
generic computational basis for this radically new view of diagrams.
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Medieval and Renaissance Manuscripts in Australia: researching and relating Australia's manuscript holdings to new technologies and new readers. Building on the productive partnership forged with the State Library of Victoria in the presentation of a recent large-scale manuscript exhibition, this project will research the Medieval and Renaissance manuscripts in Australia with reference to the interests of scholars and the general public. National and community benefits include access online to t ....Medieval and Renaissance Manuscripts in Australia: researching and relating Australia's manuscript holdings to new technologies and new readers. Building on the productive partnership forged with the State Library of Victoria in the presentation of a recent large-scale manuscript exhibition, this project will research the Medieval and Renaissance manuscripts in Australia with reference to the interests of scholars and the general public. National and community benefits include access online to this precious heritage material and its global connections, and communication of research findings in publications and events designed for a variety of readers and audiences. The project will foster collaboration between curators, librarians and academic scholars and ensure Australia's timely participation in important international initiatives in this fieldRead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668542
Funder
Australian Research Council
Funding Amount
$425,000.00
Summary
Multimedia Computing, Production, Management and Distribution for HDTV and its Applications. Australia is the first country to launch digital TV nationally. Increasingly, this platform will be used for consuming multimedia information; also the HDTV infrastructure is being applied to other domains such as telemedicine/e-Health to lower costs and improve effectiveness. For Australia to be a step ahead in the development of these applications that are beneficial to a wider community, we have to lo ....Multimedia Computing, Production, Management and Distribution for HDTV and its Applications. Australia is the first country to launch digital TV nationally. Increasingly, this platform will be used for consuming multimedia information; also the HDTV infrastructure is being applied to other domains such as telemedicine/e-Health to lower costs and improve effectiveness. For Australia to be a step ahead in the development of these applications that are beneficial to a wider community, we have to look forward and establish adequate infrastructure for the development of needed applications of the future. It is strongly believed that by doing so we can position ourselves ahead of other communities in anticipating and providing essential services to our modern society and this in turn will greatly benefit the Australian economy.Read moreRead less
Birth Weight, Adult Weight And Podocyte Depletion.
Funder
National Health and Medical Research Council
Funding Amount
$796,252.00
Summary
A major role of our kidneys is to filter our blood. A key cell type in our kidney filters is an octopus-shaped cell known as the podocyte. If we are not born with enough podocytes, or if the filters grow too large after birth due for example to excessive weight gain, the podocytes cannot adequately filter the blood, and this can lead to kidney disease. We will measure podocyte endowment at birth, and assess the effects of weight gain and loss after birth on podocyte features and kidney health.
Enriching digital history: new approaches to content development and delivery using the Dictionary of Sydney. The project will maximise the value of public investment in digital history resources by developing new methods of sharing and re-using content between systems and inviting and managing community participation. It will develop methods of preserving the community's investment in history exhibitions after they are taken down, and promote engagement with Sydney's history through delivery of ....Enriching digital history: new approaches to content development and delivery using the Dictionary of Sydney. The project will maximise the value of public investment in digital history resources by developing new methods of sharing and re-using content between systems and inviting and managing community participation. It will develop methods of preserving the community's investment in history exhibitions after they are taken down, and promote engagement with Sydney's history through delivery of historical information on “smartphones” in situ within the city. It will generate new content for, and reduce content development costs for a major public resource, the Dictionary of Sydney, and showcase Australian Humanities eResearch by delivering new approaches to content creation and delivery which will be of value to the international research community.Read moreRead less
A Unified Grid Programming Methodology for Global e-Science. This project will contribute to the national benefit in three important ways. First, we will build a set of novel e-Science applications as demonstrator projects in areas of national priority. These will have enormous economic impact in areas ranging from environmental management to health. Second, we will build software infrastructure that will have both commercial and strategic value in its own right. Third, we shall build a critical ....A Unified Grid Programming Methodology for Global e-Science. This project will contribute to the national benefit in three important ways. First, we will build a set of novel e-Science applications as demonstrator projects in areas of national priority. These will have enormous economic impact in areas ranging from environmental management to health. Second, we will build software infrastructure that will have both commercial and strategic value in its own right. Third, we shall build a critical mass of expertise that bridges the physical sciences and computer science. The support provided to this proposal will allow multi-disciplinary teams to address scientific problems of significant scale.Read moreRead less
Adaptive and Integrated Resource Allocation. By leveraging progress in communication technologies, adaptive and integrated optimization systems will open innovative application areas critical to Australia, yet outside the scope of existing optimization technology. For instance, they will dispatch and reallocate ambulances in real time, help contain pandemics, allocate resources dynamically to extinguish bushfires, and assist in failure recovery of energy infrastrutures. These systems will also s ....Adaptive and Integrated Resource Allocation. By leveraging progress in communication technologies, adaptive and integrated optimization systems will open innovative application areas critical to Australia, yet outside the scope of existing optimization technology. For instance, they will dispatch and reallocate ambulances in real time, help contain pandemics, allocate resources dynamically to extinguish bushfires, and assist in failure recovery of energy infrastrutures. These systems will also solve existing logistics and manufacturing applications better, making these industries more effective and reactive. The project also aims at establishing a center of excellence in optimization in Melbourne with an international reputation in research, teaching, and industrial collaboration.Read moreRead less
Nuanced recollection and representation: the political and rhetorical strategies of The Peterborough Chronicle. This study will enhance our understanding of essential aspects of historical writing in Anglo-Saxon and early Norman England. The analysis, to be presented in a digital facsimile presentation of this invaluable historical document, will be published in Oxford University's new Bodleian Digital Texts Series. This series, produced at The University of Melbourne with The Bodleian Library ....Nuanced recollection and representation: the political and rhetorical strategies of The Peterborough Chronicle. This study will enhance our understanding of essential aspects of historical writing in Anglo-Saxon and early Norman England. The analysis, to be presented in a digital facsimile presentation of this invaluable historical document, will be published in Oxford University's new Bodleian Digital Texts Series. This series, produced at The University of Melbourne with The Bodleian Library as collaborator, sets the standard internationally for the digital analysis and presentation of materials preserved in manuscript form, and consequently is establishing the University as a centre of excellence for this kind of work.Read moreRead less
A scalable debugging framework for petascale computers. Supercomputing underpins a wide range of areas of importance to the Australian economy; mining, agriculture, engineering, medical research and pharmaceutical development to name a few. It is of critical importance that software solutions in these areas behave correctly and do not generate erroneous results. This project will develop software tools and techniques that make it possible to detect and locate errors as software is converted to r ....A scalable debugging framework for petascale computers. Supercomputing underpins a wide range of areas of importance to the Australian economy; mining, agriculture, engineering, medical research and pharmaceutical development to name a few. It is of critical importance that software solutions in these areas behave correctly and do not generate erroneous results. This project will develop software tools and techniques that make it possible to detect and locate errors as software is converted to run on the next generation of 'petascale' supercomputers. We will deploy the tools both commercially through our industry partner, and also on national high performance computing facilities.Read moreRead less
Environmental Influences In The Establishment Of The Epigenetic Landscape In Children
Funder
National Health and Medical Research Council
Funding Amount
$695,097.00
Summary
The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells ....The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells use epigenetic changes to help control how they grow and develop. Evidence suggests a direct link between diet and environmental influences on our epigenetic profile. Recent research has traced the origins of many of the health problems of adult life back to the earliest periods of development _ to the time spent in the womb and the first few years of life. If we are born with a low birth weight, we are more likely to get sick later in life. Overwhelming evidence exists that the environment in the womb is critical for a healthy birth weight (and health in later life) and it is thought that epigenetics may be the missing link between this environment, low birth weight, and therefore health in later life. In addition, mounting evidence supports a general link between epigenetic de-regulation and predisposition to disease. However, the timing and the overall contribution of environmental- genetic influences to the establishment of faulty epigenetic markings remain largely unknown. Twins are the best model to study this link as they share similar (but not identical environments) and some share identical genetic makeup. Using twins, Dr Jeffrey Craig and his team will investigate the factors in the prenatal environment that modify specific cells, leading to low birth weight and increase disease risk later in life. They predict that this occurs via specific changes in gene activity caused by epigenetic disruption.Read moreRead less