Implementation Of Negative Pressure For Acute Paediatric Burns
Funder
National Health and Medical Research Council
Funding Amount
$1,410,476.00
Summary
Over 4000 children present to our burns services every year. Contemporary burn care aims to speed up a patients time to healing which directly avoids the child's risk of developing a scar. We know that applying negative pressure wound therapy (NPWT) to a child's burn within 72 hours post injury will improve a child's time to healing, decreasing the risk of scarring & cost of care. Co-developing a NPWT Pathway and implementation strategies will improve outcomes for childhood burns nationally.
The Australian Peritoneal Dialysis Outcomes And Practice Patterns Study (PDOPPS)
Funder
National Health and Medical Research Council
Funding Amount
$489,749.00
Summary
Peritoneal dialysis (PD) is a form of home dialysis that is both substantially cheaper and associated with better early survival than standard hospital-based haemodialysis. Its use in Australia has been severely limited by poor outcomes compared to the rest of the world. This international study aims to identify “real world” PD centre practices that will lead to better outcomes for Australian patients, greater uptake of home dialysis and health savings of tens of millions of dollars annually.
Early Introduction Of Foods Into Infant Weaning Diets To Induce Oral Tolerance And Prevent Food Allergies.
Funder
National Health and Medical Research Council
Funding Amount
$143,660.00
Summary
Food allergies can be life threatening, and with no treatment, prevention is crucial. Traditional advice for babies whose parents have allergies has been to delay the introduction of allergy causing foods. However, recent research has questioned this approach. In this study I plan to investigate whether the early introduction of fish and eggs in the weaning diet can reduce the incidence of allergy. The results will be crucial to determine the best approach to reduce the risk of food allergy.
Paediatric Emergency Medicine Centre Of Research Excellence (PEM-CRE)
Funder
National Health and Medical Research Council
Funding Amount
$2,673,400.00
Summary
The Paediatric Research in Emergency Departments International Collaborative (PREDICT) is an existing research network. By coordinating the Paediatric Emergency Medicine Centre of Research Excellence PREDICT will provide evidence to fill knowledge gaps in paediatric emergency care, develop better pathways to improve practice in the Emergency Department, and create a new ability to translate knowledge to improve care of children in Australasian emergency departments.
A Novel Diabetic Retinopathy Screening Model Based On Pathology Services (Ret-Path) For People With Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$764,273.00
Summary
Most vision loss from diabetic retinopathy, a severe complication of diabetes, can be prevented by early detection. However, with no recognized eye screening procedure, up to half of Australians with diabetes do not have a regular eye check. We have successfully piloted a new eye screening model using pathology centres as an opportunistic catchment point. In this project, we will demonstrate the overall effectiveness and economic benefits of this novel eye screening model in urban and rural Vict ....Most vision loss from diabetic retinopathy, a severe complication of diabetes, can be prevented by early detection. However, with no recognized eye screening procedure, up to half of Australians with diabetes do not have a regular eye check. We have successfully piloted a new eye screening model using pathology centres as an opportunistic catchment point. In this project, we will demonstrate the overall effectiveness and economic benefits of this novel eye screening model in urban and rural Victoria for people with diabtetes.Read moreRead less
Multi-site Randomised Controlled Trial Of Fluoxetine In Children And Adolescents With Autism.
Funder
National Health and Medical Research Council
Funding Amount
$499,482.00
Summary
Fluoxetine is a medication that is increasingly used in children with autism in an attempt to control repetitive behaviours, which substantially interfere with daily functioning and quality of life. However clinicians working in the field of autism and goverment regulatory bodies (such as the TGA) require evidence of the efficacy of fluoxetine for this indication. This study aims to determine this, thereby addressing an important gap in clinical knowledge.
A Multi-centre RCT Of An Open Lung Strategy Including Permissive Hypercapnia, Alveloar Recruitment, And Low Airway Pressure In Patients With ARDS
Funder
National Health and Medical Research Council
Funding Amount
$1,041,070.00
Summary
Acute respiratory distress syndrome (ARDS) is a severe inflammatory condition of the lungs that complicates many critical illnesses and is associated with high mortality. Inappropriate settings of the mechanical ventilator can lead to a worsening outcome. The aim of this Phase II study is to compare the clinical efficiency of a novel ventilation strategy to reduce the duration of mechanical ventilation in survivors, including several lung protective settings, to that of current standard care.
Comparing The Effectiveness Of Selective Laser Trabeculoplasty With Topical Medication For The Treatment Of Primary Angle Closure Glaucoma: A Multicentred, Prospective, Randomized Controlled Clinical Trial.
Funder
National Health and Medical Research Council
Funding Amount
$639,888.00
Summary
The main treatment of glaucoma, an eye condition which causes peripheral vision loss and blindness, involves the use of eye drops. However, these are expensive, have considerable side effects, and impact negatively on daily living. Laser has recently been proposed as an alternative treatment and, in this project, we will investigate the effectiveness of laser compared to medication. We anticipate laser will be more cost effective, safer, and have a positive impact on quality of life compared to ....The main treatment of glaucoma, an eye condition which causes peripheral vision loss and blindness, involves the use of eye drops. However, these are expensive, have considerable side effects, and impact negatively on daily living. Laser has recently been proposed as an alternative treatment and, in this project, we will investigate the effectiveness of laser compared to medication. We anticipate laser will be more cost effective, safer, and have a positive impact on quality of life compared to eye drops.Read moreRead less
Vaginal Progesterone For The Prevention Of Neonatal Respiratory Distress Syndrome - A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$935,107.00
Summary
Respiratory distress syndrome is a significant problem for babies born preterm. For these babies, a significant number will require support for their breathing. These babies are also at increased risk of dying, and in survivors, there is a risk of long-term disability. It is uncertain if giving vaginal progesterone therapy during pregnancy to women who have had a previous preterm birth can reduce these risks.