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Safeguarding coral reef fisheries for future food security. This Fellowship aims to address the vulnerability of coral reef fisheries in Australia and the Indo-Pacific by identifying fishery targets that benefit human nutrition and will persist despite declining coral habitats and rising water temperature. This project will advance knowledge on coral and fish responses to increasingly frequent marine heatwaves, using novel methodologies rooted in ecological modelling, experimental marine biology ....Safeguarding coral reef fisheries for future food security. This Fellowship aims to address the vulnerability of coral reef fisheries in Australia and the Indo-Pacific by identifying fishery targets that benefit human nutrition and will persist despite declining coral habitats and rising water temperature. This project will advance knowledge on coral and fish responses to increasingly frequent marine heatwaves, using novel methodologies rooted in ecological modelling, experimental marine biology and climate forecasting. Expected outcomes include (i) a comprehensive toolbox for improved management of coral reefs and associated fisheries in Australia and beyond, and (ii) an integrated socio-ecological model for predicting coral reef fishery responses under environmental change.Read moreRead less
Improved theory and practice in econometric modelling of nonlinear spatial time series. Modern Australia faces many challenges in economic and global climate changes, which require advanced statistical technologies in modeling and forecasting of econometric spatial time series data. This project will provide flexible models and methods that enable practitioners to more accurately measure and manage economic and climatic risks.
Molecular hallmarks of androgen receptor targeting in prostate cancer. There is a critical need in oncology drug development for better biomarkers of response to prostate cancer therapies, clinically to assist with treatment decision making, and pre-clinically to facilitate translation of emerging agents into clinical practice. Using a unique explant culture model, this project will identify protein and lipid markers that can be used to accurately and reliably assess response to androgen recepto ....Molecular hallmarks of androgen receptor targeting in prostate cancer. There is a critical need in oncology drug development for better biomarkers of response to prostate cancer therapies, clinically to assist with treatment decision making, and pre-clinically to facilitate translation of emerging agents into clinical practice. Using a unique explant culture model, this project will identify protein and lipid markers that can be used to accurately and reliably assess response to androgen receptor (AR)-targeting therapies in human prostate tumours. The identification and functional assessment of these biomarkers will identify those that can be used as surrogate endpoints in clinical trials, facilitate earlier approval of investigational agents and lead to improved options for therapeutic management of prostate cancer.Read moreRead less
Utilizing the geological record to constrain the response of marine ecosystems and global carbon cycling to warming and de-oxygenation. Earth history is punctuated by a huge variety of transitions and perturbations in climate, biogeochemical cycling, and ecosystems, some of which may hold direct future-relevant information. In the oceans, these are closely linked in a complex web of feedbacks, as well as to the oxygenation of the ocean and the ultimate geological fate of excessive carbon release ....Utilizing the geological record to constrain the response of marine ecosystems and global carbon cycling to warming and de-oxygenation. Earth history is punctuated by a huge variety of transitions and perturbations in climate, biogeochemical cycling, and ecosystems, some of which may hold direct future-relevant information. In the oceans, these are closely linked in a complex web of feedbacks, as well as to the oxygenation of the ocean and the ultimate geological fate of excessive carbon released into the atmosphere – burial of carbon in sediments. This project will develop a computer model representation of this coupled carbon-climate-life system and test this against the geological record, explore the causes and consequences of carbon release events and extinctions as well as how the ocean floor delivery and preservation of organic carbon responds.Read moreRead less
Methods for establishing cumulative CO2 emission budgets for Australia. Limiting global warming requires curbing cumulative carbon emissions. However, we do not know how the quasi-linear relationship between cumulative carbon dioxide emissions and maximal warming is modulated by other climate-relevant gases (for example, sulphur oxide or Methane) nor have we quantified the relationship in sufficient detail for aligning national and international policy strategies. This project will develop new m ....Methods for establishing cumulative CO2 emission budgets for Australia. Limiting global warming requires curbing cumulative carbon emissions. However, we do not know how the quasi-linear relationship between cumulative carbon dioxide emissions and maximal warming is modulated by other climate-relevant gases (for example, sulphur oxide or Methane) nor have we quantified the relationship in sufficient detail for aligning national and international policy strategies. This project will develop new methods to establish global emission budgets for various climate targets and likelihoods. Options for Australia’s share will be quantified on the basis of effort-sharing proposals. This research is vital for Australian policy makers, the energy sector, and the public in order to plan for coming decades.Read moreRead less
Breaking Gondwana: interplay between tectonics, climate and resources. The project aims to reconstruct 250 million years of landscape evolution in response to rifting and break-up of the Gondwana supercontinent, using the innovative approach of combining regional thermochronology with global plate tectonic models. From these reconstructions, the time-integrated record of exhumation and erosion at the continental margins will be revealed at an unprecedented scale. The main expected outcome will b ....Breaking Gondwana: interplay between tectonics, climate and resources. The project aims to reconstruct 250 million years of landscape evolution in response to rifting and break-up of the Gondwana supercontinent, using the innovative approach of combining regional thermochronology with global plate tectonic models. From these reconstructions, the time-integrated record of exhumation and erosion at the continental margins will be revealed at an unprecedented scale. The main expected outcome will be a deep time archive of the relationships between tectonic forcing, continental erosion and the global climate, which may assist predictions and debate on future climate change. The outcomes will also provide economic benefits as they will inform on the exhumation and preservation of (critical) mineral resources.Read moreRead less
How do mechanical cues regulate tissue renewal and tumour progression? Imbalances between cell production and cell death in tissues can be catastrophic, leading to major global health issues such as cancer. This project will use modified mice and protein-protein interaction based techniques to identify how changes in the mechanical properties of tissues regulate the balance between cell production and cell death.
Design of novel nanoporous semiconductor materials for clean environment and energy. This project will develop a low cost nanoporous semiconductor device for the capture and conversion of CO2 into fuels by using water and sunlight. This novel approach will deliver a low cost technology that offers clean energy and will help to mitigate global warming.
Open framework organic materials for CO2 capture and conversion. The reduction of CO2 emissions from coal-fired power plants is a technological challenge of global significance. This project will address this challenge by developing a unique system, based upon open framework materials, that will selectively capture CO2 from gas streams and then catalyse its transformation into industrially useful chemicals.
The emotional construction of self representation. This project develops and defends the novel idea that self representation is an artefact of emotional processing. The account will involve case studies of psychiatric disorder characterised by developmental or acquired problems of self representation such as depersonalisation disorder and personality disorders.