Advancing vegetation classification and mapping to meet conservation needs. The project aims to develop advanced statistical and modelling techniques to classify and map vegetation over very large areas, using the most extensive and detailed vegetation data set in Australia and new methods to evaluate these classifications. Such classifications and maps provide the data needed to make biodiversity conservation decisions, yet current operational methods are limited over very large areas, and cann ....Advancing vegetation classification and mapping to meet conservation needs. The project aims to develop advanced statistical and modelling techniques to classify and map vegetation over very large areas, using the most extensive and detailed vegetation data set in Australia and new methods to evaluate these classifications. Such classifications and maps provide the data needed to make biodiversity conservation decisions, yet current operational methods are limited over very large areas, and cannot deal with varied sources of uncertainty. Expected outcomes and benefits include a fine-scale vegetation classification and map for almost a million square kilometres, and associated analytical tools and guidelines for large-scale vegetation classification and global mapping.Read moreRead less
Clinical Impact Of Clonal Pseudomonas Aeruginosa In Cystic Fibrosis
Funder
National Health and Medical Research Council
Funding Amount
$547,238.00
Summary
In patients with cystic fibrosis (CF), the normal defence mechanisms are compromised by an inherent genetic fault which results in an extremely sticky and dehydrated mucus. The respiratory system is unable to eradicate microbes (infection) from the lungs of patients with CF which begin to multiply and cause infection and inflammation. Recurring infections are treated with multiple courses of antibiotics and frequent hospitalisation and eventually result in premature death. This study focuses on ....In patients with cystic fibrosis (CF), the normal defence mechanisms are compromised by an inherent genetic fault which results in an extremely sticky and dehydrated mucus. The respiratory system is unable to eradicate microbes (infection) from the lungs of patients with CF which begin to multiply and cause infection and inflammation. Recurring infections are treated with multiple courses of antibiotics and frequent hospitalisation and eventually result in premature death. This study focuses on the major bacterial problem, Pseudomonas aeruginosa. Several studies from Australia and the UK, including our own have shown that about 30% to 45% of patients share the same strain of Pseudomonas aeruginosa within a centre. We know that two dominant strains of Pseudomonas aeruginosa are found in CF centres on the eastern board of Australia. This is unexpected as this bacterium is usually acquired from the environment. The emergence of these clonal strains is causing increasing anxiety in the CF community. This study is designed to provide vitally needed information on the clinical implications of being infected by an clonal strain of Pseudomonas aeruginosa and the risk factors for the acquisition of an clonal strain. This new information will provide a rationale basis for the need for changes to infection control policies (including patient segregation), better outcome predictors for patients infected with clonal strain of Pseudomonas aeruginosa.Read moreRead less
Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, ....Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, unprecedented in scope and resolution. Outcomes include an open access database to quantify and visualise intra-urban air pollution and human exposure and develop air quality maps and smoke pollution management tools. It is expected to advance the evidence-based management of air as a resource, increasing economic prosperity and enhancing human health and quality of life.Read moreRead less
Advanced techniques for imaging radar interferometry. The Earth's surface is changing all the time, both slowly and dramatically, due to activities such as groundwater extraction, underground mining and earthquakes. This project will develop advanced, cost-effective and accurate imaging radar techniques that can measure subtle surface changes frequently, in order to safeguard significant infrastructure.
Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian po ....Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian population. Accurate and objective per-capita based consumption and release estimates for a wide range of chemicals is intended to provide a baseline against which to measure changes in our chemosphere.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100083
Funder
Australian Research Council
Funding Amount
$310,000.00
Summary
A 4D habitat-modelling facility to support marine ecological research. The loss and modification of natural habitats is a major threat to biodiversity that requires evidence-based management supported by excellent science. To this end, this project will create a facility for 4D habitat modelling (i.e. assessing changes in 3D habitat structure over time) that will underpin research innovation in marine systems. The new aerial and subtidal image acquisition technology will also be used to accurate ....A 4D habitat-modelling facility to support marine ecological research. The loss and modification of natural habitats is a major threat to biodiversity that requires evidence-based management supported by excellent science. To this end, this project will create a facility for 4D habitat modelling (i.e. assessing changes in 3D habitat structure over time) that will underpin research innovation in marine systems. The new aerial and subtidal image acquisition technology will also be used to accurately measure changes in marine plants and algae over time, improve habitats provided by coastal protection infrastructure and support ecological field research. The new equipment will allow scaling up of field experiments and monitoring to enhance their impact and capacity to support effective management.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100155
Funder
Australian Research Council
Funding Amount
$648,000.00
Summary
NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an i ....NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an integrated software and hardware system called NanoMin which incorporates a spectral deconvolution engine combined with a mineral spectra database. A key limitation in understanding complex materials is sub-micron to nanometer scale spatial variability of mineralogical phases. Imaging and quantifying these phases is now possible with the NanoMin system. This promises to open up petrological, geobiological, and materials science research in complex fine-grained materials.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150100009
Funder
Australian Research Council
Funding Amount
$389,476.00
Summary
Toxic Oceans: How do anthropogenic pollutants impact vital marine microbes? Environmental pollution threatens the sustainability of the world's oceans. However, we still do not understand how pollution affects primary producers at the base of oceanic food chains. This project aims to provide the first account of how common chemical pollutants (herbicides, plastic leachates and crude oil) affect key groups of marine photosynthetic bacteria. As these microbes underpin entire marine food webs, unde ....Toxic Oceans: How do anthropogenic pollutants impact vital marine microbes? Environmental pollution threatens the sustainability of the world's oceans. However, we still do not understand how pollution affects primary producers at the base of oceanic food chains. This project aims to provide the first account of how common chemical pollutants (herbicides, plastic leachates and crude oil) affect key groups of marine photosynthetic bacteria. As these microbes underpin entire marine food webs, understanding their responses is crucial to monitoring and mitigating the impact of pollutants on ocean ecosystems. The aim is to design and validate novel, rapid environmental stress assays, based on gene expression profiling. This represents a pioneering new application of gene monitoring techniques to ocean conservation.Read moreRead less
An International Clinical Trial To Evaluate New Therapies To Improve Survival Of Children With Relapsed Acute Lymphoblastic Leukaemia
Funder
National Health and Medical Research Council
Funding Amount
$1,567,500.00
Summary
Children who relapse with childhood leukaemia have only a 50% chance of being alive after 5 years. We will participate in a new international trial involving most European and all Australian and New Zealand childhood oncology centres, to test the effectiveness of promising new treatments and to perform biological studies which should enable doctors in future to pick the best treatment for each of these patients.
Quantifying the flux of fugitive greenhouse gasses associated with coal seam gas and calibrating it to natural baseline and anthropogenic sources. Recent studies show that fugitive methane emissions associated with coal seam gas extraction pose a source of greenhouse gasses. In addition to the possible environmental impacts of methane emissions, quantifying the magnitude of emissions has potentially significant implications for future tax liabilities that could change the economics of the unconv ....Quantifying the flux of fugitive greenhouse gasses associated with coal seam gas and calibrating it to natural baseline and anthropogenic sources. Recent studies show that fugitive methane emissions associated with coal seam gas extraction pose a source of greenhouse gasses. In addition to the possible environmental impacts of methane emissions, quantifying the magnitude of emissions has potentially significant implications for future tax liabilities that could change the economics of the unconventional energy boom in Australia. The proposed research by an interdisciplinary team representing regulators, industry, and university researchers would establish a methodology for quantifying the flux of methane from gas fields. It would establish the range of natural baselines and determine the major sources of methane emissions using newly available highly sensitive instruments.Read moreRead less