Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the rel ....Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the release of cryptic genetic variation that can allow novel morphologies to evolve in new environments. The project expects to provide further understanding of how species may potentially adapt to environmental stresses in the future, including climate change.Read moreRead less
Evolution of sensory systems in the dark biosphere. This project utilises a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. We aim to characterise and investigate the evolution of chemosensory and circadian rhythm genes, which play critical roles in the fitness of animals, including the ability to find food and mates in a ....Evolution of sensory systems in the dark biosphere. This project utilises a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. We aim to characterise and investigate the evolution of chemosensory and circadian rhythm genes, which play critical roles in the fitness of animals, including the ability to find food and mates in a dark, thermally stable environment. Knowledge of chemosensory and circadian genetic systems and how they dynamically evolve is fundamental to a variety of fields, including the process of speciation and biological adaptation (for example, to permanent darkness, pollutants and insecticides).Read moreRead less
How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex ....How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex traits.Read moreRead less
How does timing affect mammalian brain development and evolution? This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understandi ....How does timing affect mammalian brain development and evolution? This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understanding the dynamics of developmental systems that shape complex brain traits includes establishing new developmental paradigms in evolutionary theory, generating new tools to investigate and manipulate brain gene expression in vivo, and the potential discovery of the causes of neurodevelopmental dysfunction.Read moreRead less
Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the pl ....Non-equilibrium presolvation electron processes at the gas-liquid interface. The interaction of low-temperature plasma electrons with liquids has served as a reducing agent in various technological applications in water treatment, agriculture, biofuels and medicine. Predictive control of the plasma-liquid interface is essential to unlocking the potential of these applications, and this has been limited by the absence of the relevant non-equilibrium transport theory describing electrons at the plasma-liquid interface together with fundamental data describing electron interactions with liquids. The project will develop a state of the art presolvation electron transport model informed by world first measurements of electron cross-sections for radicals and liquids and apply it to model plasma electrochemistry processes.Read moreRead less
Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of posit ....Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of positron transport in PET. The project will allow validation of predictions from the model by undertaking experiments in liquid water.Read moreRead less
Breaking Gondwana: interplay between tectonics, climate and resources. The project aims to reconstruct 250 million years of landscape evolution in response to rifting and break-up of the Gondwana supercontinent, using the innovative approach of combining regional thermochronology with global plate tectonic models. From these reconstructions, the time-integrated record of exhumation and erosion at the continental margins will be revealed at an unprecedented scale. The main expected outcome will b ....Breaking Gondwana: interplay between tectonics, climate and resources. The project aims to reconstruct 250 million years of landscape evolution in response to rifting and break-up of the Gondwana supercontinent, using the innovative approach of combining regional thermochronology with global plate tectonic models. From these reconstructions, the time-integrated record of exhumation and erosion at the continental margins will be revealed at an unprecedented scale. The main expected outcome will be a deep time archive of the relationships between tectonic forcing, continental erosion and the global climate, which may assist predictions and debate on future climate change. The outcomes will also provide economic benefits as they will inform on the exhumation and preservation of (critical) mineral resources.Read moreRead less
Finding the missing links in salt and water transport in plants. Grain crops and horticultural plants use proteins called aquaporins to move water across cell membranes, but a group of these proteins can also transport some important nutrient ions as well as toxic sodium ions. This project aims to reveal the molecular pathways that regulate water and ion transport via aquaporins using advanced techniques in biophysics and molecular biology. These results will provide novel insights into how plan ....Finding the missing links in salt and water transport in plants. Grain crops and horticultural plants use proteins called aquaporins to move water across cell membranes, but a group of these proteins can also transport some important nutrient ions as well as toxic sodium ions. This project aims to reveal the molecular pathways that regulate water and ion transport via aquaporins using advanced techniques in biophysics and molecular biology. These results will provide novel insights into how plants coordinate and adapt to changing water and salt conditions, addressing a missing link in how ions and water move in and out of plant vacuoles. Benefits include an expanded, innovative range of targets for plant breeding programs to improve plant productivity in our changing climate.Read moreRead less
Molecular movies using time-resolved momentum spectroscopies. This project aims to use time-resolved momentum spectroscopies to take snapshots of chemical and physical processes as they evolve in time. This project expects to use these molecular movies to track the changes to electron motion after they have absorbed light. Expected outcomes of this project include understanding how the motion of electrons can drive physical processes and induce chemical changes. This will provide significant ben ....Molecular movies using time-resolved momentum spectroscopies. This project aims to use time-resolved momentum spectroscopies to take snapshots of chemical and physical processes as they evolve in time. This project expects to use these molecular movies to track the changes to electron motion after they have absorbed light. Expected outcomes of this project include understanding how the motion of electrons can drive physical processes and induce chemical changes. This will provide significant benefits through expanding knowledge that will assist in controlling chemical reactions and developing technologies with improved performance, such as sensors and solar cells. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100625
Funder
Australian Research Council
Funding Amount
$446,700.00
Summary
Integrated slab-mode beam engineering for handheld terahertz systems. Current dominant system architectures for terahertz waves are adapted from other ranges, leading to critical bottlenecks. This project will address this with a new integration platform that is tailored to the particular needs of terahertz waves. This requires advances in the emerging field of micro-scale integrated optics, combined with antenna-theory principles, semiconductor science, and advanced microfabrication to incorpor ....Integrated slab-mode beam engineering for handheld terahertz systems. Current dominant system architectures for terahertz waves are adapted from other ranges, leading to critical bottlenecks. This project will address this with a new integration platform that is tailored to the particular needs of terahertz waves. This requires advances in the emerging field of micro-scale integrated optics, combined with antenna-theory principles, semiconductor science, and advanced microfabrication to incorporate active devices. Novel spatially-dependent dispersion engineering techniques will also be pioneered for phased-array-free beamforming. This will enable a broad variety of all-in-one handheld systems for practical applications of terahertz waves such as noninvasive standoff sensing and self-aligning wireless links.Read moreRead less