How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex ....How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex traits.Read moreRead less
Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of posit ....Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of positron transport in PET. The project will allow validation of predictions from the model by undertaking experiments in liquid water.Read moreRead less
Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interact ....Novel source of excited metastable atoms for Atom Trap Trace Analysis. This project aims to understand and to control light-induced processes in atoms by using finely shaped and tailored laser pulses, focusing on efficient production of excited metastable atoms. This is critical for efficient Atom Trap Trace Analysis, the most advanced technique for dating ground water and geological samples. Expected outcomes of this project include new and enhanced knowledge of physics of light-matter interactions, developing an efficient, clean source of excited metastable atoms, and integrating that source into the Australian National Facility for dating geological samples. This should provide significant benefits, such as significant improvement of operational efficiency and productivity of that facility.Read moreRead less
Imaging the spatial distribution of forces that bind quarks to a proton. This project will perform supercomputer simulations to resolve the distribution of forces acting on quarks inside the proton. New knowledge will be generated in the area of fundamental strong-interaction physics by developing innovative approaches to image novel features that have not been possible in the past. The outcomes will therefore open new research possibilities by expanding the capacity of the international communi ....Imaging the spatial distribution of forces that bind quarks to a proton. This project will perform supercomputer simulations to resolve the distribution of forces acting on quarks inside the proton. New knowledge will be generated in the area of fundamental strong-interaction physics by developing innovative approaches to image novel features that have not been possible in the past. The outcomes will therefore open new research possibilities by expanding the capacity of the international community to study strong interaction physics—including direct relevance to experimental research at the recently-upgraded Jefferson Lab in the US. In analogy to Rutherford's atomic model, the results will have benefit to future generations of humanity with a deeper understanding of the structure of matter.Read moreRead less
Supercomputing the tomography of the proton. This project aims to produce theoretical determinations of the quark and gluon distributions of the proton through advanced supercomputer simulations. The project will generate new knowledge in the area of fundamental strong-interaction physics by developing innovative approaches to image structures that have not been possible in the past. This project expects to expand the capacity of the international community to study strong interaction physics, i ....Supercomputing the tomography of the proton. This project aims to produce theoretical determinations of the quark and gluon distributions of the proton through advanced supercomputer simulations. The project will generate new knowledge in the area of fundamental strong-interaction physics by developing innovative approaches to image structures that have not been possible in the past. This project expects to expand the capacity of the international community to study strong interaction physics, including direct relevance to experimental research at the recently-upgraded Jefferson Lab in the US. In analogy to Rutherford's atomic model, the results will have benefit to future generations of humanity with a deeper understanding of the structure of matter.Read moreRead less
Emergent Phenomena in the Foundation of Matter. This project aims to explore the finite-matter-density features of the relativistic field theory of the strong interactions, Quantum Chromodynamics (QCD). Drawing on national supercomputing resources, this project will undertake QCD calculations of unprecedented complexity to discover emergent phenomena in the ground-state quantum fields that form the foundation of matter. By studying their evolution under temperature and matter density and explori ....Emergent Phenomena in the Foundation of Matter. This project aims to explore the finite-matter-density features of the relativistic field theory of the strong interactions, Quantum Chromodynamics (QCD). Drawing on national supercomputing resources, this project will undertake QCD calculations of unprecedented complexity to discover emergent phenomena in the ground-state quantum fields that form the foundation of matter. By studying their evolution under temperature and matter density and exploring their contribution to the structure of the nucleon and its excitations, the research will advance theoretical understanding and challenge experimental programs. Benefits include transferable skills in advanced analytical techniques, high-performance computing, and scientific data visualisation.Read moreRead less
ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresour ....ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresources to capitalise upon emergent and rapidly expanding domestic and global markets. Anticipated outcomes include industry uptake of innovative plant forms, foods, technologies, and commodities; and an ambitious education and international co-ordination agenda to position Australia as a global leader in research supporting Space habitation.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less