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2026 ARDC Annual Survey is now open!

The Australian Research Data Commons (ARDC) invites you to participate in a short survey about your interaction with the ARDC and use of our national research infrastructure and services. The survey will take approximately 5 minutes and is anonymous. It’s open to anyone who uses our digital research infrastructure services including Reasearch Link Australia.

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Research Topic : Molecular basis of disease
Scheme : Practitioner Fellowships
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  • Researchers (0)
  • Funded Activities (40)
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  • Funded Activity

    Imaging Neurodegenerative Disease

    Funder
    National Health and Medical Research Council
    Funding Amount
    $317,153.00
    Summary
    Advances in positron emission tomography now allow specific pathological features of many brain diseases such as Alzheimer's disease to be measured with a brain scan during life. This Fellowship will assist Professor Rowe and his team in their world leading work on new PET scanning techniques to improve diagnosis and assist the development of treatment for Alzheimer's and other degenerative diseases of the brain.
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    Funded Activity

    Disease Registry Based Approaches To Determining Molecular Risk Factors For Glaucoma Blindness, And Applying Them In Clinical Practice

    Funder
    National Health and Medical Research Council
    Funding Amount
    $406,355.00
    Summary
    The Practitioner-Fellow has drawn together very large cohorts of patients from Australia, New Zealand and now internationally who have lost vision from Glaucoma and complications of Diabetes to determine the contributing factors. He has successfully identified major clinical and genetic risk factors for these diseases, and is now applying the knowledge to patients in early stages of disease, so that earlier and more aggressive treatment high risk individuals can lead to improved outcomes.
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    Funded Activity

    Conducting Clinical Research In Chronic Kidney Disease

    Funder
    National Health and Medical Research Council
    Funding Amount
    $569,219.00
    Summary
    The burden of Chronic Kidney Disease (CKD) is large, increasing, and ultimately unsustainable. One in ten Australians have CKD which puts them at higher risk of cardiovascular disease and cancer, and a higher likelihood of an early death. CKD also has a negative impact on people's lifestyles and relationships. Practitioner Fellowship support will allow me relief from my clinical commitments to invest in promising lines of new enquiry to support people with CKD and their carers.
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    Funded Activity

    Guaranteeing Survival Into Adulthood, Physical Health And Psychological Well-being To Children Born With Single Ventricles.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $342,773.00
    Summary
    Being born with a single pumping heart chamber is the most severe heart condition but thanks to several operations we can see them survive. A growing population of young functional adults now face an uncertain future and we have no options for them. A/Pr Y d’Udekem is a leading paediatric cardiac surgeon. His research aims to provide the medications, reinterventions and artificial hearts that are necessary to give them a longer and fulfilling life.
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    Funded Activity

    Molecular Imaging As A Critical Tool In Discovery Of The Basis Of Tumour Heterogeneity And Developing Novel Therapies To Overcome Therapeutic Resistance

    Funder
    National Health and Medical Research Council
    Funding Amount
    $467,961.00
    Summary
    Determining treatment options for cancer currently relies on the size and extent of tumour deposits on imaging, combined with a biopsy. However, this approach fails to recognise the ability of tumours to evolve components that are, or become, resistant to treatment. My laboratory uses advanced molecular imaging, targeted biopsies, animal models and genetic analysis to detect and understand the basis of such resistance and thereby develop new, targeted treatments to improve patient outcomes.
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    Funded Activity

    Translating Advances In Molecular Oncology Into Improved Care For Patients With Haematological Malignancies

    Funder
    National Health and Medical Research Council
    Funding Amount
    $411,327.00
    Summary
    The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.
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    Funded Activity

    Translating Molecular Pathology Into Cancer Diagnostics

    Funder
    National Health and Medical Research Council
    Funding Amount
    $479,882.00
    Summary
    The aim of this research is focussed on translation of basic science through to the clinic by introducing novel cancer diagnostics and technologies. Other integral aims are to identify new changes in DNA and other cancer cell markers in patients, assess the clinical utility of these as biomarkers (surrogates of cancer behaviour) and to conduct novel clinical trials with newly identified molecular targets of cancer and new therapeutics and combinations to assess their efficacy.
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    Funded Activity

    Development Of Systemic Therapies To Improve Response And Prevent Resistance In The Treatment Of Melanoma

    Funder
    National Health and Medical Research Council
    Funding Amount
    $569,219.00
    Summary
    This program of research utilises the unique resources at Melanoma Institute Australia (MIA) to understand the biology of prolonged response and resistance to novel drug therapies used in metastatic melanoma, a cancer that now leads the field in the discovery of new targets for therapeutic manipulation. This program also aims to create new methods to efficiently test and develop drug therapy combinations in humans to improve patient outcomes further or prevent metastatic melanoma altogether.
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    Funded Activity

    Practitioner Fellowship

    Funder
    National Health and Medical Research Council
    Funding Amount
    $420,541.00
    Summary
    I am a thoracic physician undertaking clinical translational research in lung and thoracic cancers
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    Funded Activity

    Diagnosis And Treatment Of Congenital Infection

    Funder
    National Health and Medical Research Council
    Funding Amount
    $317,153.00
    Summary
    Viral infections that mothers catch during pregnancy still cause much illness in babies either in the womb, or after birth. One of these infections called CMV causes more babies to be born with malformation in Australia than any other infection, and is second only to cerebral palsy as a cause of serious problems in babies. Our studies are examining CMV in mothers and babies, leading to better diagnostic tests, researching use of existing and new antiviral drugs to reduce infection in these mothe .... Viral infections that mothers catch during pregnancy still cause much illness in babies either in the womb, or after birth. One of these infections called CMV causes more babies to be born with malformation in Australia than any other infection, and is second only to cerebral palsy as a cause of serious problems in babies. Our studies are examining CMV in mothers and babies, leading to better diagnostic tests, researching use of existing and new antiviral drugs to reduce infection in these mothers and babies.
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