Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a ....Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a red blood cell line. Simultaneously, this project aims to generate fundamental insights into mechanisms of human gene regulation. The technological and biological outcomes of this project will be of benefit for future gene editing applications.Read moreRead less
China's Industrialisation and Demand for Energy and Minerals. Understanding China's medium and long-term growth prospects and the implications for both demand and supply of resources are critically important to Australian economic policy and performance, as well as to investment decisions of Australian resource producers, and professional decisions of Australians in a wide range of occupations. Analysis of the medium and long-term demand for resources from China would be beneficial for Australia ....China's Industrialisation and Demand for Energy and Minerals. Understanding China's medium and long-term growth prospects and the implications for both demand and supply of resources are critically important to Australian economic policy and performance, as well as to investment decisions of Australian resource producers, and professional decisions of Australians in a wide range of occupations. Analysis of the medium and long-term demand for resources from China would be beneficial for Australian resource industries. It is also important to Australian budget, education and infrastructure policy. Increasing Chinese demand for resources will be critical in shaping global environmental policies.Read moreRead less
Flavour enhancing functional feeds for farmed Barramundi. This project aims to improve the flavour quality of Australian farmed barramundi through developing novel functional feeds. The project expects to expand our fundamental knowledge of flavour enhancement, whilst providing practical benefits with respect to final product quality. The project will enable industry to achieve higher product quality benchmarks, towards the ultimate goal of improving the marketability of barramundi both locally ....Flavour enhancing functional feeds for farmed Barramundi. This project aims to improve the flavour quality of Australian farmed barramundi through developing novel functional feeds. The project expects to expand our fundamental knowledge of flavour enhancement, whilst providing practical benefits with respect to final product quality. The project will enable industry to achieve higher product quality benchmarks, towards the ultimate goal of improving the marketability of barramundi both locally and overseas. This project will provide significant benefits to the Australian barramundi industry by increasing product values, thereby facilitating an economically sustainable growth of this important regional industry.Read moreRead less
Auctions of Standing Trees. This project is critical to the ecological well-being of Australia. Standing trees are extremely important in Australia because they prevent soil erosion and stabilize water tables; their location influences fire risks. Much timber is sold at auction. While it is possible and desirable to learn how other nations use auctions to sell standing trees, information from those locales needs to be used with care when adapting it to the Australian experience. The project ....Auctions of Standing Trees. This project is critical to the ecological well-being of Australia. Standing trees are extremely important in Australia because they prevent soil erosion and stabilize water tables; their location influences fire risks. Much timber is sold at auction. While it is possible and desirable to learn how other nations use auctions to sell standing trees, information from those locales needs to be used with care when adapting it to the Australian experience. The project will use state-of-the art theory and methods to implement novel public policy. It will also develop expertise necessary to implement modern economic methods in environmental policy settings.Read moreRead less
Insoluble-fibre enriched beverages. Insoluble-fibre enriched beverages. This project aims to develop healthy new beverages, by studying the effect of chemistry and physical interactions of insoluble dietary fibre with other food ingredients. Insoluble fibre reduces the risk of chronic diseases, including cardiovascular disease, cancer and diabetes. This project will research how insoluble-fibre linked phytochemicals behave in complex matrices and contribute to malodorous flavours; and design adv ....Insoluble-fibre enriched beverages. Insoluble-fibre enriched beverages. This project aims to develop healthy new beverages, by studying the effect of chemistry and physical interactions of insoluble dietary fibre with other food ingredients. Insoluble fibre reduces the risk of chronic diseases, including cardiovascular disease, cancer and diabetes. This project will research how insoluble-fibre linked phytochemicals behave in complex matrices and contribute to malodorous flavours; and design advanced experimental protocols to prevent undesirable sensory characteristics in liquid systems.Read moreRead less
Systemic and adaptive water governance: lessons for Australia from China and South Africa. The way we manage catchments under climate change is one of Australia’s major public policy challenges. This project will give new direction to catchment management by developing a science-policy linked, systemic and adaptive water governance mechanism. By recommending policy options for more sustainable water use and creating favourable social-institutional factors for the implementation of these policy o ....Systemic and adaptive water governance: lessons for Australia from China and South Africa. The way we manage catchments under climate change is one of Australia’s major public policy challenges. This project will give new direction to catchment management by developing a science-policy linked, systemic and adaptive water governance mechanism. By recommending policy options for more sustainable water use and creating favourable social-institutional factors for the implementation of these policy options in two Australian catchment authorities through comparative and parallel research in China and South Africa. This project directly addresses the national priority goals of “Water - a critical resource” and “Responding to climate change”. This project will also stress Australia's important role in this globally significant issue. Read moreRead less
Interactions between Social, Economic and Regulatory Aspects of Residential Household Water Consumption. Water security is at crisis point in many Australian regions and overseas. This research will engage citizens in water conservation and management, and will have a number of significant outcomes that will benefit national and community interests. These include (1) devising effective water management strategies that are acceptable to residential customers in two contrasting water service regi ....Interactions between Social, Economic and Regulatory Aspects of Residential Household Water Consumption. Water security is at crisis point in many Australian regions and overseas. This research will engage citizens in water conservation and management, and will have a number of significant outcomes that will benefit national and community interests. These include (1) devising effective water management strategies that are acceptable to residential customers in two contrasting water service regions, (2) a generalisable and replicable model of residential household water consumption that highlights the issues of public trust in current water governance arrangements, and (3) recommendations for communication and behaviour change interventions that promote water-use efficiency and conservation, and are sensitive to regional differences.Read moreRead less
Novel methods for the production of micronutrient-enriched rice. The increasingly productive Australian rice industry generated AUD$1 billion revenue in 2012. By targeting a rice gene that we recently identified as a key regulator of iron uptake and transport, this project will produce high value, micronutrient-enriched rice grain to improve the nutritional health of people in Australia and throughout the world.
Advanced plant breeding and food manufacturing for healthier bread. This project aims to generate bread containing high amounts of biologically available iron through targeted manipulation of plant-derived phytonutrients at several points along the wheat-to-bread supply chain. The project expects to generate new knowledge for developing healthier bread and address consumer demands for value-added food products. Anticipated outcomes are novel plant breeding and food manufacturing techniques that ....Advanced plant breeding and food manufacturing for healthier bread. This project aims to generate bread containing high amounts of biologically available iron through targeted manipulation of plant-derived phytonutrients at several points along the wheat-to-bread supply chain. The project expects to generate new knowledge for developing healthier bread and address consumer demands for value-added food products. Anticipated outcomes are novel plant breeding and food manufacturing techniques that enhance the nutritional composition of wheat grain and bread making products, resulting in higher-value agricultural commodities and breads. The project should benefit bread retailers and crop growers involved in Australia’s $4.7 billion bread market and reduce the environmental impacts of bread production.Read moreRead less
Australia’s first direct-detection dark matter search, at Stawell Gold Mine. This project aims to develop an underground integrated laboratory at Stawell Gold Mine in Victoria to host the Southern Hemisphere's first-ever direct-detection dark matter experiment. Following the Higgs boson discovery, the direct detection of dark matter is seen as the next major challenge for particle physics. This project sees Australian physicists team up with local and international partners in research and indus ....Australia’s first direct-detection dark matter search, at Stawell Gold Mine. This project aims to develop an underground integrated laboratory at Stawell Gold Mine in Victoria to host the Southern Hemisphere's first-ever direct-detection dark matter experiment. Following the Higgs boson discovery, the direct detection of dark matter is seen as the next major challenge for particle physics. This project sees Australian physicists team up with local and international partners in research and industry to join the search for dark matter. This Australian experiment aims to help to confirm or deny current results from Northern Hemisphere experiments. As the mine nears the end of its working life as a gold mine, this project is expected to benefit the local economy and provide opportunities for education and outreach.Read moreRead less