New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software ....New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software implementations. Both nonsmooth and integer optimisation problems have a good mathematical basis, but there are "gaps"; existing methods cannot always solve real industrial problems. This project will deliver better methods, built on better theory, and so will yield better solutions for important applications.Read moreRead less
Involving children in social research: balancing the risks and benefits. There is a growing consensus that children's involvement in social research is important, but considerable uncertainty remains around children's inclusion in research on 'sensitive' issues, reflecting concerns about how to balance children's protection with their participation. Key to this are deeply embedded assumptions and beliefs about children and childhood, especially concerning notions of capacity, agency, vulnerabili ....Involving children in social research: balancing the risks and benefits. There is a growing consensus that children's involvement in social research is important, but considerable uncertainty remains around children's inclusion in research on 'sensitive' issues, reflecting concerns about how to balance children's protection with their participation. Key to this are deeply embedded assumptions and beliefs about children and childhood, especially concerning notions of capacity, agency, vulnerability, dependency and the like. This project aims to better understand and address the tensions between the protection of children and their participation in research, and to explore how ethics committees, parents, other gatekeepers and children themselves manage and navigate these tensions.Read moreRead less
To Improve The Quality And Access To Dialysis Treatments By Indigenous Australians From Remote Areas By Using A Patient-centred Approach To Determine The Cost-effectiveness Of Treatment Models That Include The Health, Social And Economic Impact
Funder
National Health and Medical Research Council
Funding Amount
$1,195,023.00
Summary
Compared to other Australians, Indigenous people from remote areas suffer disproportionately from kidney disease. In order to access treatment they must often relocate, sometimes permanently to urban areas. Communities advocate for services closer to home but most health providers see remote area delivery as prohibitively costly. The study will assess the relative cost-benefits of more patient-centered models of care that are inclusive of impacts on patients, families and communities.
Improving Delivery Of Secondary Prophylaxis For Rheumatic Heart Disease: A Stepped-wedge, Community-randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,913,074.00
Summary
Rheumatic heart disease (RHD) is a major health problem in Indigenous communities. Continued progress in controlling RHD requires an understanding of how to improve delivery of regular injections of penicillin - secondary prophylaxis (SP). We will evaluate a systems-based approach to improving delivery of SP, using a stepped-wedge trial in 12 communities in NT and Qld. If successful, this model will provide a practical and transferable model.
A Population-based Record Linkage Study Of The Impact Of Chlamydia Infection On Reproductive Health In Women
Funder
National Health and Medical Research Council
Funding Amount
$405,114.00
Summary
Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Au ....Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Australia.Read moreRead less
SCALE-C: Strategies For Hepatitis C Testing And Treatment In Aboriginal Communities That Lead To Elimination
Funder
National Health and Medical Research Council
Funding Amount
$2,175,170.00
Summary
Prevalence of hepatitis C infection within the Aboriginal population is among the highest of any identifiable population in Australia. Highly effective, direct-acting antiviral (DAA) therapy, and their listing on the PBS in 2016 has revolutionised HCV clinical management in Australia. The SCALE-C study will evaluate an established test and treat model to rapidly scale-up DAA within four Aboriginal communities to determine both impact on community prevalence and ongoing transmission.
Integrating choice set formation and taste heterogeneity in market segmentation. This project develops a new model of consumer decision-making to provide managerial insights related to market segmentation, product portfolio optimisation and marketing communication strategies. The model can be specified for a particular product category using data collected from a novel elicitation instrument developed as part of this project.
Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements ....Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements of many trains on a congested rail network to improve timekeeping, smooth the flow of traffic, increase capacity and reduce energy use.Read moreRead less
Real-time scheduling of trains to control peak electricity demand. This project aims to develop new scheduling and control methods that will enable railways to reduce their demand for electricity during peak demand periods, without undue disruption to the timetable.
These new methods and systems will integrate with—and expand the capabilities of—an Australian train control system that is used by railways around the world. This will enable better management of electricity within a region and be ....Real-time scheduling of trains to control peak electricity demand. This project aims to develop new scheduling and control methods that will enable railways to reduce their demand for electricity during peak demand periods, without undue disruption to the timetable.
These new methods and systems will integrate with—and expand the capabilities of—an Australian train control system that is used by railways around the world. This will enable better management of electricity within a region and better use of renewable energy sources, with significant cost savings for railways and the wider community.Read moreRead less
CENTRE OF RESEARCH EXCELLENCE TO REDUCE INEQUALITY IN HEART DISEASE
Funder
National Health and Medical Research Council
Funding Amount
$2,607,253.00
Summary
There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health ....There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health care services.Read moreRead less