Statistical Methods And Algorithms For Analysis Of High-throughput Genetics And Genomics Platforms
Funder
National Health and Medical Research Council
Funding Amount
$1,557,500.00
Summary
Through rapid advances in high-throughput -omics technologies, the number of phenotypes and the number of genotypes in gene mapping studies are or will be orders of magnitudes larger than in previous studies. Current algorithms and analysis methods have not kept up with the speed of data collection, nor has the training of qualified researchers. We will develop quantitative trait loci (fine) mapping analysis methods and bioinformatics algorithms and train (post)graduates in these research areas.
Population-based Genetic Screening For Klinefelters Syndrome: A Critical Analysis
Funder
National Health and Medical Research Council
Funding Amount
$75,468.00
Summary
Klinefelter’s Syndrome (KS) is a common and important genetic condition affecting males, yet 70% are never diagnosed. Males with KS are always infertile and may have hormone imbalances, breast development, decreased facial and pubic hair, and varying levels of cognitive, social, behavioural and learning difficulties. Treatment and intervention options are available, if KS is diagnosed early enough. Screening for the condition is possible - but what would the advantages and disadvantages of this ....Klinefelter’s Syndrome (KS) is a common and important genetic condition affecting males, yet 70% are never diagnosed. Males with KS are always infertile and may have hormone imbalances, breast development, decreased facial and pubic hair, and varying levels of cognitive, social, behavioural and learning difficulties. Treatment and intervention options are available, if KS is diagnosed early enough. Screening for the condition is possible - but what would the advantages and disadvantages of this be?Read moreRead less
Making A Difference Building Research Capacity For Health Interventions To Improve Aboriginal Health
Funder
National Health and Medical Research Council
Funding Amount
$2,717,836.00
Summary
The program will build skills in the development and evaluation of intervention programs to improve Aboriginal health outcomes. It will focus on the health of Aboriginal people living in urban and regional centres and examine (i) child and adolescent health and (ii) chronic disease. The program is lead by two indigenous people and will build capacity in six indigenous early career researchers and a further three from non-indigenous backgrounds. The Aboriginal Health and Medical Research Council ....The program will build skills in the development and evaluation of intervention programs to improve Aboriginal health outcomes. It will focus on the health of Aboriginal people living in urban and regional centres and examine (i) child and adolescent health and (ii) chronic disease. The program is lead by two indigenous people and will build capacity in six indigenous early career researchers and a further three from non-indigenous backgrounds. The Aboriginal Health and Medical Research Council of NSW and 11 Aboriginal health services are partners through existing research programs. The program draws on extensive skills in intervention research among the Lead Applicants and will provide opportunities for the Team Investigators to work on major funded research programs in Aboriginal health. The program will develop skills in intervention research capable of providing an evidence base to inform Aboriginal health policy. It will build capacity in (i) the development of research partnerships with Aboriginal communities; (ii) the identification of potentially effective interventions; (iii) the investigation of the impact of health interventions; and, (iv) the integration of research with policy.Read moreRead less
Creating A Culture Of Safety And Respect: A Controlled, Mixed Methods Study Of The Effectiveness Of A Behavioural Accountability Intervention To Reduce Unprofessional Behaviours
Funder
National Health and Medical Research Council
Funding Amount
$875,978.00
Summary
Unprofessional behaviours among health professionals are common and are associated with increased patient dissatisfaction and medicolegal risk. Addressing these behaviours is a national issue. Ethos is a structured accountability system involving a process of early, non-punitive and tiered intervention and will be introduced across four Australian hospitals. This research will be the first controlled study to assess the effectiveness of the Ethos program to improve patient safety in Australia.
The Impact Of Living Kidney Donation On Donor-recipient Relationships
Funder
National Health and Medical Research Council
Funding Amount
$99,684.00
Summary
The purpose of this study is to explore the expectations and experiences of the impact of living kidney donation on donor-recipient relationships. There is very little research on this topic. This study will use qualitative methodology (face-to-face interviews and diary entries) to inform the design of written-booklet support resources which will subsequently be evaluated. This can help to improve and protect donor and recipient outcomes in living kidney donation.
Patterns Of Care And Experience Of Care For Adolescents And Young Adults With Cancer
Funder
National Health and Medical Research Council
Funding Amount
$669,096.00
Summary
There is increasing concern, across several countries, that outcomes of care for adolescents and young adults (AYAs) with cancer are not optimal. This project aims to improve outcomes of care for AYAs with cancer by providing information about the best way to organise health services. It will do this by describing patterns of care for 700 AYA patients with cancer; providing detailed data on experiences with care for 300 patients; and conducting in-depth qualitative interviews.
Effects Of Medical Pluralism And Cross-border Drug Flows On The Health-seeking Behaviour Of Indian-Australians And Anglo-Australians With Depression
Funder
National Health and Medical Research Council
Funding Amount
$308,664.00
Summary
Taking medication for depression varies by cultural groups. This project will examine how Indian-Australians and Anglo-Australians access and use antidepressant treatments from biomedicine and complementary and alternative medicine. The project looks at the effects of these medicines and treatments on the body and wellbeing and how some treatments could be integrated to deliver more holistic and culturally sensitive forms of care.