Discovery Early Career Researcher Award - Grant ID: DE150101655
Funder
Australian Research Council
Funding Amount
$297,036.00
Summary
Discriminative detection and quantification of cancer imaging biomarkers. This project aims to develop a new framework for the detection and quantification of cancer biomarkers in diagnostic and histopathology images with discriminative modelling of intrinsic structures. The framework will be the first computerised solution to provide automated, quantitative annotations of cancer imaging biomarkers at the macroscopic and microscopic levels to support standardised reporting of image interpretatio ....Discriminative detection and quantification of cancer imaging biomarkers. This project aims to develop a new framework for the detection and quantification of cancer biomarkers in diagnostic and histopathology images with discriminative modelling of intrinsic structures. The framework will be the first computerised solution to provide automated, quantitative annotations of cancer imaging biomarkers at the macroscopic and microscopic levels to support standardised reporting of image interpretation. It will help to alleviate the inter-observer variability and time-consuming process of manual analysis. The project aims to advance fundamental biomedical imaging research in generalised visual structure extraction and classification, and enable large-scale translational research in systems pathology for personalised cancer care.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101518
Funder
Australian Research Council
Funding Amount
$294,111.00
Summary
Multi-Object Recognition of Biomedical Images via Holistic Ontology. This project seeks to advance the development of new biomedical image recognition and analysis solutions by associating biomedical images with biomedical knowledge and personalised data. The provision of accurate and robust multi-object recognition and analysis from biomedical image data is a fundamental requirement for biomedical imaging applications. This project aims to improve the recognition and analysis of anatomical and ....Multi-Object Recognition of Biomedical Images via Holistic Ontology. This project seeks to advance the development of new biomedical image recognition and analysis solutions by associating biomedical images with biomedical knowledge and personalised data. The provision of accurate and robust multi-object recognition and analysis from biomedical image data is a fundamental requirement for biomedical imaging applications. This project aims to improve the recognition and analysis of anatomical and functional structures from biomedical images with ‘holistic ontology’ modelling that represents a multi-level biological, physiological, and anatomical knowledge base. The project will potentially have application in many health care areas, such as computer aided diagnosis, image-guided surgery planning, and image-based disease modelling.Read moreRead less
Advanced techniques for imaging radar interferometry. The Earth's surface is changing all the time, both slowly and dramatically, due to activities such as groundwater extraction, underground mining and earthquakes. This project will develop advanced, cost-effective and accurate imaging radar techniques that can measure subtle surface changes frequently, in order to safeguard significant infrastructure.
Biomedical Visual Image Analytics for Multi-disciplinary Retrieval. The project aims to develop a framework to provide users with the interactive access to information that is necessary for the best collaborative decision-making. Visual analytics theory is becoming increasing valuable for managing ‘big data’ because it can provide interactive and intuitive understanding of the rich information embedded within complex data and decision support systems. There are, however, fundamental challenges t ....Biomedical Visual Image Analytics for Multi-disciplinary Retrieval. The project aims to develop a framework to provide users with the interactive access to information that is necessary for the best collaborative decision-making. Visual analytics theory is becoming increasing valuable for managing ‘big data’ because it can provide interactive and intuitive understanding of the rich information embedded within complex data and decision support systems. There are, however, fundamental challenges that currently prevent visual analytics from being routinely applied to multi-disciplinary collaboration, which is now ‘the norm’ to solve large complicated problems where there is significant social impact. This project aims to address these challenges and improve visual analytics theory by developing a biomedical visual image analytics framework that enables interactive information retrieval of multidisciplinary databases.Read moreRead less
A probabilistic framework for nonlinear dimensionality reduction algorithms. The Twin Measures Framework is a novel platform for analysing existing dimensionality reduction methods and the invention of new ones. This research will radically improve image analysis, with beneficial applications from pharmaceutical drug design through to border protection.
Multiscale integration of imaging and omics data. This project aims to integrate multiscale imaging and molecular data to characterise disease in patients. Modern healthcare needs to embrace ‘big (health) data’s potential to address an ageing population’s increasing healthcare demands and the inefficiencies and waste in patient treatment. This project expects to pioneer basic science research in methodologies to integrate, correlate and then derive knowledge from multi-scale data, to characteris ....Multiscale integration of imaging and omics data. This project aims to integrate multiscale imaging and molecular data to characterise disease in patients. Modern healthcare needs to embrace ‘big (health) data’s potential to address an ageing population’s increasing healthcare demands and the inefficiencies and waste in patient treatment. This project expects to pioneer basic science research in methodologies to integrate, correlate and then derive knowledge from multi-scale data, to characterise the mechanisms of disease in individual patients, in space and time. Its integrated model is expected to form the basis of a framework for individualised patient disease analysis.Read moreRead less
A data science framework for modelling disease patterns from medical images. A data science framework for modelling disease patterns from medical images. This project aims to extract models of disease patterns from medical imaging data, using deep learning, smart image processing, machine learning, and statistical modelling to quantify and model patterns conventional methods cannot detect. These disease models are expected to improve understanding of particular diseases and enable precision medi ....A data science framework for modelling disease patterns from medical images. A data science framework for modelling disease patterns from medical images. This project aims to extract models of disease patterns from medical imaging data, using deep learning, smart image processing, machine learning, and statistical modelling to quantify and model patterns conventional methods cannot detect. These disease models are expected to improve understanding of particular diseases and enable precision medicine, which recognises that there are important differences between individuals with a particular disease, and that when patients are separated into sub-populations with similar disease patterns, treatment can be tailored to these sub-populations.Read moreRead less
Automated analysis of multi-modal medical data using deep belief networks. This project will develop an improved breast cancer computer-aided diagnosis (CAD) system that incorporates mammography, ultrasound and magnetic resonance imaging. This system will be based on recently developed deep learning techniques, which have the capacity to process multi-modal data in a unified and optimal manner. The advantage of this technique is that it is able to automatically learn both the relevant features t ....Automated analysis of multi-modal medical data using deep belief networks. This project will develop an improved breast cancer computer-aided diagnosis (CAD) system that incorporates mammography, ultrasound and magnetic resonance imaging. This system will be based on recently developed deep learning techniques, which have the capacity to process multi-modal data in a unified and optimal manner. The advantage of this technique is that it is able to automatically learn both the relevant features to analyse in each modality and the hidden relationships between them. The use of deep belief networks has produced promising results in several fields, such as speech recognition, and so this project believes that our approach has the potential to improve both the sensitivity and specificity of breast cancer detection.Read moreRead less
Omni-modality medical image analysis and visualisation. The term ‘Omni’-modality imaging (OMI) has been coined to describe the integration of multiple, complementary medical imaging modalities. However, there is currently a lack of an appropriate means to assimilate and derive maximum benefit from these integrated data. This project aims to provide a new approach to OMI data analysis and visualisation, by deriving a novel ‘level of relevance’ from the overlapping anatomical and pathological stru ....Omni-modality medical image analysis and visualisation. The term ‘Omni’-modality imaging (OMI) has been coined to describe the integration of multiple, complementary medical imaging modalities. However, there is currently a lack of an appropriate means to assimilate and derive maximum benefit from these integrated data. This project aims to provide a new approach to OMI data analysis and visualisation, by deriving a novel ‘level of relevance’ from the overlapping anatomical and pathological structures in the data which will be used to suppress superfluous data and highlight the most relevant data to maximise the information gained from the OMI data. Further, OMI visualisation is proposed to efficiently navigate through the overlapping data.Read moreRead less
Precise recognition for automated harvesting and grading of strawberries. This project aims to improve automated strawberry harvesting to enable industrial harvesters to be deployed for commercial use and to lift the productivity of the Australian fruit industry. Precise recognition and grading of strawberries is a major obstacle in developing fully-automated commercial strawberry harvesting systems. Current colour-based fruit recognition techniques have intrinsic limitations in meeting the need ....Precise recognition for automated harvesting and grading of strawberries. This project aims to improve automated strawberry harvesting to enable industrial harvesters to be deployed for commercial use and to lift the productivity of the Australian fruit industry. Precise recognition and grading of strawberries is a major obstacle in developing fully-automated commercial strawberry harvesting systems. Current colour-based fruit recognition techniques have intrinsic limitations in meeting the needs of automatic strawberry harvesting. This project aims to investigate high-level syntactic recognition approaches that embed high-order texture patterns of ripe fruit and hyperspectral analysis techniques to achieve partially occluded fruit recognition and grading of fruit at the level required by commercial production.Read moreRead less