Mosquito-borne alphaviruses such as Ross River and chikungunya viruses cause widespread epidemics and exert extreme pressure on the public health systems of affected regions. Alphaviruses spreads to joints and triggers a severe disease in those affected. There are no effective treatments or vaccines. The project will investigate virus-host interaction at the bite site. The outcome will be new knowledge to treat infection at the mosquito bite site to prevent joint disease.
Special Research Initiatives - Grant ID: SR0354702
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Microbial Resources Research Network. The Australian Microbial Resources Research Network will provide integrated access to Australian collections of microorganisms and electronic access to bioinformation databases to meet national strategic needs for microbiological resources and to support the competitive development of the life sciences and biotechnology industries in Australia. The network will promote collaborative interactions and accelerate the discovery of Australian microorg ....Australian Microbial Resources Research Network. The Australian Microbial Resources Research Network will provide integrated access to Australian collections of microorganisms and electronic access to bioinformation databases to meet national strategic needs for microbiological resources and to support the competitive development of the life sciences and biotechnology industries in Australia. The network will promote collaborative interactions and accelerate the discovery of Australian microorganisms and microbial genomic information for innovative biotechnology and create new opportunities for bioindustries. The Network will link researchers and foster the discovery and exploitation of Australian microbial resources and make these resources and associated information available for applications in research, industry and education.Read moreRead less
Novel Insights Into The Pathobiology Of Alphavirus Infections
Funder
National Health and Medical Research Council
Funding Amount
$827,660.00
Summary
Infections with mosquito-borne viruses are increasing at an alarming rate worldwide. Ross River virus is endemic in parts of Australia, PNG and Pacific islands, while chikungunya virus is distributed globally and causes recurrent pandemics that involve millions of people. These viruses cause severe musculoskeletal disease for several months after infection. This project aims to establish how these viruses interact with the human host to cause disease and may provide a basis for new treatments.
Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laborator ....Development and implementation of biodiversity information for sustainable management of South Australian groundwater. Clean potable water is one of the most important resources for human health and a successful economy. Increasingly, subterranean aquifers are used for storage and recovery of water. These aquifers contain dynamic ecosystems, but little is known about species composition or about the importance of the presence of various species for water quality. We will use the latest laboratory techniques and DNA identification methods to provide a template for determining ground water diversity and food web dynamics throughout Australia. This project will lead to a better understanding of how to manage ground water in a sustainable manner.Read moreRead less
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Novel oxygen sensing tools for monitoring the effects of dredging on Australian seagrass communities. Seagrass meadows sustain marine biodiversity and the fishing industries on Australian coasts. Dredging of ports and shipping channels is contributing to their rapid global decline. The project will use state-of-the-art technologies in bio-optics and genomics to create a toolkit for seagrass managers to make informed decisions to safeguard seagrass meadows.
A novel method for controlling microbial concrete corrosion in sewers. This project plans to use a newly discovered, low-cost and environmental benign antimicrobial agent to develop an innovative technology to control the development of corrosion-inducing sewer biofilms. Concrete sewer corrosion is a long-standing and costly problem for the water industry. Microbial hydrogen sulfide oxidation on concrete surfaces plays a critical role. The technology will be designed to prevent corrosion of new ....A novel method for controlling microbial concrete corrosion in sewers. This project plans to use a newly discovered, low-cost and environmental benign antimicrobial agent to develop an innovative technology to control the development of corrosion-inducing sewer biofilms. Concrete sewer corrosion is a long-standing and costly problem for the water industry. Microbial hydrogen sulfide oxidation on concrete surfaces plays a critical role. The technology will be designed to prevent corrosion of new concrete sewers by adding a precursor chemical into the cement, or to slow down the corrosion of existing sewers by infrequently (once every one to few years) spraying the precursor chemical directly onto the concrete surface. Potentially, the project will substantially reduce sewer corrosion.Read moreRead less
ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use ....ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use state-of-the-art technology, including use of synchrotron radiation at the Monash-based Australian Synchrotron facility from 2007.Read moreRead less
Special Research Initiatives - Grant ID: SR0354619
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Microbial Genomics Research Network. The Australian Microbial Genomics Research Network aims to bring together Australian scientists with complementary expertise in microbial genomics within two ARC Centres, a Ramaciotti Centre and four institutions across three states. This initiative will involve the strategy and planning of the proposed Network.
ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes i ....ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes involved in the control of key cellular processes. The Centre will also determine the shapes of key molecules and their interactions. Practical outcomes will include new veterinary vaccines and the identification of novel antimicrobial targets.Read moreRead less