Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnol ....Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnology, bioremediation, and synthetic biology where evolution can be inhibited or exploited, respectively.Read moreRead less
Role of mRNA polyadenylation control in gene expression. Several benefits would come from a more complete understanding of the function of the messenger RNA poly(A) tail. It is frequently targeted by mechanisms that control cellular protein synthesis. This is most evident in developmental biology, where tail length control regulates maternal mRNA expression. Our previous work suggests that it has much wider importance for cellular function than previously thought and thus its study will produce ....Role of mRNA polyadenylation control in gene expression. Several benefits would come from a more complete understanding of the function of the messenger RNA poly(A) tail. It is frequently targeted by mechanisms that control cellular protein synthesis. This is most evident in developmental biology, where tail length control regulates maternal mRNA expression. Our previous work suggests that it has much wider importance for cellular function than previously thought and thus its study will produce knowledge of broad relevance to modern life sciences and its applications in medicine and biotechnology. Finally, a better understanding of yeast cellular biology is of benefit to the food and biotechnology sector of industry.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100046
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Capturing highly beneficial and persistent legume symbionts. This project aims to investigate impacts of climate change on the survival of symbiotic soil bacteria and the nutritional benefits they provide plants, using molecular technology. This project will generate new knowledge about the process of adaptation in symbiotic bacteria, by measuring genomic changes. Expected outcomes of this project include enhanced capacity to design ecological or genetic manipulations of soil bacteria to augment ....Capturing highly beneficial and persistent legume symbionts. This project aims to investigate impacts of climate change on the survival of symbiotic soil bacteria and the nutritional benefits they provide plants, using molecular technology. This project will generate new knowledge about the process of adaptation in symbiotic bacteria, by measuring genomic changes. Expected outcomes of this project include enhanced capacity to design ecological or genetic manipulations of soil bacteria to augment plant survival and health. Anticipated benefits include enhanced woodland restoration in a biodiversity hotspot, options to mitigate habitat damage from climate change, and strategies to increase agricultural productivity with less fertiliser.Read moreRead less