Discovery Early Career Researcher Award - Grant ID: DE150101574
Funder
Australian Research Council
Funding Amount
$368,583.00
Summary
Evolution and Adaptation of the Human Microbiome. The bacteria within the human body (microbiome) are vital to human health, and alterations to these intricate microbial communities are now associated with disease. Using ancient DNA, this project aims to examine the evolutionary history of the human microbiome by exploring ancient bacterial communities preserved in calcified dental plaque (calculus) over the past 10 000 years. This will provide valuable information that reveals how these bacteri ....Evolution and Adaptation of the Human Microbiome. The bacteria within the human body (microbiome) are vital to human health, and alterations to these intricate microbial communities are now associated with disease. Using ancient DNA, this project aims to examine the evolutionary history of the human microbiome by exploring ancient bacterial communities preserved in calcified dental plaque (calculus) over the past 10 000 years. This will provide valuable information that reveals how these bacterial communities respond to alterations in human diet, environment, culture, and location. By monitoring changes in a natural modern system, this project aims to determine how these microbial communities established themselves within the human body, elucidating how the microbiome may respond in the future.Read moreRead less
Stories from the past: the impact of industrialisation on the human microbiome. This project aims to explore the history and origin of ‘Industrial’ diseases such as obesity, diabetes, heart disease and autism. Non-communicable, ‘Industrial’ diseases are rising at an alarming rate in Australia, and changes to the beneficial microorganisms within the human body (microbiota) may be to blame. This project will explore how human microbiota have changed over the past 100 years in response to cultural, ....Stories from the past: the impact of industrialisation on the human microbiome. This project aims to explore the history and origin of ‘Industrial’ diseases such as obesity, diabetes, heart disease and autism. Non-communicable, ‘Industrial’ diseases are rising at an alarming rate in Australia, and changes to the beneficial microorganisms within the human body (microbiota) may be to blame. This project will explore how human microbiota have changed over the past 100 years in response to cultural, environmental, and lifestyle factors linked with Industrialisation. This approach will allow stories from the past to inform modern medical treatment strategies and public health decisions in the future. The project will identify changes in environment, diet, hygiene, and medicine that have altered human microbiota in the past and sparked the Industrial disease epidemic in Australia today.Read moreRead less
Marine flatworm parasites of elasmobranchs: a unique model for experiments exploring invasion strategies, biology and specificity to help understand parasitism. Primitive parasites with simple life cycles from ancient hosts emphasise adaptations to parasitism. Experimental studies on live eggs and infective stages of different monogenean (flatworm) parasite species from the skin, gills and cloaca of southern fiddler rays will identify critical interactions early in parasite-host relationships t ....Marine flatworm parasites of elasmobranchs: a unique model for experiments exploring invasion strategies, biology and specificity to help understand parasitism. Primitive parasites with simple life cycles from ancient hosts emphasise adaptations to parasitism. Experimental studies on live eggs and infective stages of different monogenean (flatworm) parasite species from the skin, gills and cloaca of southern fiddler rays will identify critical interactions early in parasite-host relationships that determine whether or not parasitism occurs. Basic and applied benefits include: development of a tractable experimental system for studying parasite-host relationships; strategies to control parasites in public aquaria and aquaculture; profitable and exportable expertise; excellence and research training in basic parasitology; contributions to Australia's natural heritage collections.Read moreRead less
Behavioural syndromes and social networks in sleepy lizards. Fauna in Australian ecosystems are threatened by habitat fragmentation, changing environments and the spread of exotic pathogens. To manage these threats we need to understand the behavioural flexibility of wildlife populations. This project focuses on how individual behavioural differences can influence social networks and consequently pathogen transmission. It will help to protect our fauna from invasive diseases and contribute to su ....Behavioural syndromes and social networks in sleepy lizards. Fauna in Australian ecosystems are threatened by habitat fragmentation, changing environments and the spread of exotic pathogens. To manage these threats we need to understand the behavioural flexibility of wildlife populations. This project focuses on how individual behavioural differences can influence social networks and consequently pathogen transmission. It will help to protect our fauna from invasive diseases and contribute to sustaining biodiversity. With better knowledge of how diseases spread we can develop more effective controls of those diseases, thereby protecting wildlife species, animal populations and Australian ecosystems. Read moreRead less
Co-evolution of sociality and sex allocation: phylogenetic comparative approaches using insects. This project investigates the coevolution of sex allocation and sociality. Although linkage between these two traits has long been conjectured in evolutionary ecology, and numerous studies have investigated species-specific relationships, the question of how these two features interact over evolutionary time has not been examined. Here, we apply phylogenetic comparative approaches to determine wh ....Co-evolution of sociality and sex allocation: phylogenetic comparative approaches using insects. This project investigates the coevolution of sex allocation and sociality. Although linkage between these two traits has long been conjectured in evolutionary ecology, and numerous studies have investigated species-specific relationships, the question of how these two features interact over evolutionary time has not been examined. Here, we apply phylogenetic comparative approaches to determine whether sex allocation strategies have influenced subsequent social evolution. In particular, we extend the notion of parental manipulation to ask whether mothers have been able to use sex allocation to influence alloparental behaviour in their offspring, leading to greater levels of altruism.Read moreRead less
Origin of social parasites via sympatric speciation: testing the theory using allodapine bees as a model system. This project addresses a contentious evolutionary conjecture regarding the origin of some species and will help maintain Australia's position in the forefront of evolutionary biology and behavioural ecology. Benefits derive from developing and maintaining world class research excellence, with consequences for scientific competitiveness and training the next generation of young researc ....Origin of social parasites via sympatric speciation: testing the theory using allodapine bees as a model system. This project addresses a contentious evolutionary conjecture regarding the origin of some species and will help maintain Australia's position in the forefront of evolutionary biology and behavioural ecology. Benefits derive from developing and maintaining world class research excellence, with consequences for scientific competitiveness and training the next generation of young researchers in cutting-edge techniques. The project fosters international collaboration, important for maintaining links with the broader scientific community and fostering breadth in postgraduate training. The project will also train 3 PhD students and 1-2 honours students per year, with strong expertise in evolutionary, genetic and ecological research techniques.Read moreRead less
Lizard social networks and the spread of parasites. Australian ecosystems are continually threatened by new epidemics of diseases and parasites, some local, others from overseas. Examples include the facial tumours of Tasmanian devils and the fungus that threatens many native frog species. To manage these epidemics effectively, we must understand how they spread through animal populations. This project will help to protect our fauna from invasive diseases. It contributes to sustaining the biodiv ....Lizard social networks and the spread of parasites. Australian ecosystems are continually threatened by new epidemics of diseases and parasites, some local, others from overseas. Examples include the facial tumours of Tasmanian devils and the fungus that threatens many native frog species. To manage these epidemics effectively, we must understand how they spread through animal populations. This project will help to protect our fauna from invasive diseases. It contributes to sustaining the biodiversity of the country. With better knowledge of how diseases of wildlife spread, we can develop more effective control of those diseases thereby protecting wildlife species, animal populations and, ultimately, Australian ecosystems.Read moreRead less
The puzzle of Metazoan life history evolution: are feeding larvae always primitive? Most marine animals have a complex life-cycles with alternating pelagic larvae and benthic adults. An theory about animal life-history evolution states that feeding larvae are always primitive and larval feeding is lost but not gained. This hypothesis is based in part on studies on the 'classical' trochophore of marine worms such as Serpulidae, a group with both feeding and non-feeding larvae. We intend to establ ....The puzzle of Metazoan life history evolution: are feeding larvae always primitive? Most marine animals have a complex life-cycles with alternating pelagic larvae and benthic adults. An theory about animal life-history evolution states that feeding larvae are always primitive and larval feeding is lost but not gained. This hypothesis is based in part on studies on the 'classical' trochophore of marine worms such as Serpulidae, a group with both feeding and non-feeding larvae. We intend to establish a detailed phylogeny for Serpulidae and assess the evolution of larvae in the group. If feeding larvae are shown to be secondary this will raise doubts about established theories of animal evolution.Read moreRead less
Adapting to a changing world: mothers as drivers of evolutionary change. This project will improve our understanding of how organisms will adapt to the unprecedented speed and magnitude of human-induced environmental change. By identifying how mothers modify their offspring to better match the prevailing environment, it will address the role of mothers in directing and accelerating adaptation in our changing world.
Modes of speciation in subterranean diving beetles from calcrete aquifers of central Western Australia. Understanding speciation is a fundamental biological problem and our analyses of the diving beetles will broaden our understanding of modes of speciation and how an extraordinary biodiversity of subterranean animals (stygofauna) evolved in the limestone aquifers of central WA. The aquifers are an important source of water for pastoralists and mining companies and the limestone is also a valuab ....Modes of speciation in subterranean diving beetles from calcrete aquifers of central Western Australia. Understanding speciation is a fundamental biological problem and our analyses of the diving beetles will broaden our understanding of modes of speciation and how an extraordinary biodiversity of subterranean animals (stygofauna) evolved in the limestone aquifers of central WA. The aquifers are an important source of water for pastoralists and mining companies and the limestone is also a valuable resource, so there is a need for further research on the impacts of these uses. We will generate further knowledge of the diversity and biological significance of the stygofauna, information that is critical for the environmentally sustainable management of the aquifers and their ecosystems. Read moreRead less