New Membrane Chips For Protein Interaction Analysis. This proposal is based on a strategic partnership between Monash University and Farfield Sensors. We will create a series of new biosensors that will be used to establish a new approach to the structural analysis of membrane protein function. In particular, this technology may lead to the identification of new proteins and drug targets for therapeutic development. The long-term outcome would be the development of improved therapeutics which wo ....New Membrane Chips For Protein Interaction Analysis. This proposal is based on a strategic partnership between Monash University and Farfield Sensors. We will create a series of new biosensors that will be used to establish a new approach to the structural analysis of membrane protein function. In particular, this technology may lead to the identification of new proteins and drug targets for therapeutic development. The long-term outcome would be the development of improved therapeutics which would be coupled to potential economic returns when further commercialisation is achieved. Read moreRead less
Assembly and function of arabinogalactan-proteins: a class of proteoglycans involved in plant growth and development. We aim to define the mechanisms by which a family of cell surface proteoglycans, the arabinogalactan-proteins (AGPs), are assembled and contribute to the regulation of plant growth and development using Arabidopsis, a model system amenable to a functional genomics strategy. This will be achieved through the application of bioinformatics for gene discovery and molecular, biochemi ....Assembly and function of arabinogalactan-proteins: a class of proteoglycans involved in plant growth and development. We aim to define the mechanisms by which a family of cell surface proteoglycans, the arabinogalactan-proteins (AGPs), are assembled and contribute to the regulation of plant growth and development using Arabidopsis, a model system amenable to a functional genomics strategy. This will be achieved through the application of bioinformatics for gene discovery and molecular, biochemical and genetics approaches to define gene function. Understanding mechanisms that control plant growth and development will ultimately impact on industries (agriculture, horticulture and forestry) vital to Australia's prosperity.Read moreRead less
Assembly and function of arabinogalactan-proteins: a class of proteoglycans involved in plant growth and development. Achievements of the Objectives will specifically address National Research Priority 3 by developing breakthrough science and utilising frontier technologies with application to Australia's agri-biotechnology industries. In addition to contributing to world class research outcomes, we will train highly skilled graduates and postdoctoral fellows in functional genomics technologies, ....Assembly and function of arabinogalactan-proteins: a class of proteoglycans involved in plant growth and development. Achievements of the Objectives will specifically address National Research Priority 3 by developing breakthrough science and utilising frontier technologies with application to Australia's agri-biotechnology industries. In addition to contributing to world class research outcomes, we will train highly skilled graduates and postdoctoral fellows in functional genomics technologies, thereby contributing to the "knowledge nation".Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560722
Funder
Australian Research Council
Funding Amount
$512,744.00
Summary
High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules. This request is for a high-speed analytical ultracentrifuge equipped with sensitive absorbance, fluorescence, and interference scanning optics. The equipment, the first of its kind in Australia, would establish a world-class facility for analysing the size, shape, and stability of macromolecular complexes and their interactions in solution. This new facility will enable high through ....High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules. This request is for a high-speed analytical ultracentrifuge equipped with sensitive absorbance, fluorescence, and interference scanning optics. The equipment, the first of its kind in Australia, would establish a world-class facility for analysing the size, shape, and stability of macromolecular complexes and their interactions in solution. This new facility will enable high through-put screening of small molecules with potential as new drugs. This core platform technology will cover the range of needs from basic research through to commercialization of discovery. The equipment will support existing high quality research projects in biotechnology and provide new opportunities for post-graduate training and international collaboration.Read moreRead less
Valuations and Business Models for Biotechnology Companies. The primary aim of this project is to reduce the risk involved in investment in biotechnology companies by developing a model that will aid in a more accurate assessment of their value. This project will also develop commercialisation pathways incorporating valuation modeling techniques that will maximise the commercial potential of the intellectual capital portfolios held by biotechnology companies. By developing new models that accoun ....Valuations and Business Models for Biotechnology Companies. The primary aim of this project is to reduce the risk involved in investment in biotechnology companies by developing a model that will aid in a more accurate assessment of their value. This project will also develop commercialisation pathways incorporating valuation modeling techniques that will maximise the commercial potential of the intellectual capital portfolios held by biotechnology companies. By developing new models that account for the specific variables of the biotechnology industry, this project will contribute new knowledge and advance development of valuation models applicable to other knowledge-based industries which share characteristics such as intangible assets, high risk, complexity and uncertainty.Read moreRead less