Synthetic regulators of gene expression. RNA plays many essential roles in cells, from information transfer and regulation of gene expression to scaffolding macromolecular structures and catalysis. Despite these realisations the current approaches to manipulate RNA are limited in many respects. This project will use synthetic biology approaches to engineer synthetic regulators of RNAs in living cells. These studies will provide new tools for use in biological research and provide insights into h ....Synthetic regulators of gene expression. RNA plays many essential roles in cells, from information transfer and regulation of gene expression to scaffolding macromolecular structures and catalysis. Despite these realisations the current approaches to manipulate RNA are limited in many respects. This project will use synthetic biology approaches to engineer synthetic regulators of RNAs in living cells. These studies will provide new tools for use in biological research and provide insights into how natural proteins control gene expression. Furthermore, this project will use these tools to understand the mechanisms of how proteins are synthesised in mammalian mitochondria.Read moreRead less
Chemical signalling in the sea. This project aims to understand how eggs attract and select sperm, and how the environment influences these interactions. Differential sperm chemotaxis, a form of mate choice involving chemical signalling between eggs and sperm, has only been described in mussels, but may be a widespread form of gamete-level sexual selection. The project will study the biochemical and molecular basis of differential sperm chemotaxis in mussels, and the stability of gamete-level in ....Chemical signalling in the sea. This project aims to understand how eggs attract and select sperm, and how the environment influences these interactions. Differential sperm chemotaxis, a form of mate choice involving chemical signalling between eggs and sperm, has only been described in mussels, but may be a widespread form of gamete-level sexual selection. The project will study the biochemical and molecular basis of differential sperm chemotaxis in mussels, and the stability of gamete-level interactions under different environmental conditions. Improved fundamental knowledge of reproduction in a commercially important marine species may yield future commercial benefits for Australia’s marine food production sectorRead moreRead less
Use of Gas Expanded Liquids to Facilitate Process Intensification. The aim of this research is the utilisation of gas expanded liquids (GXLs) in technology platforms based on the principles of process intensification (PI). In order to facilitate the attainment of project objectives a comprehensive investigation of the fundamental properties of GXLs, and their interactions is proposed. A significant component of the programme is expected to be to use the knowledge obtained to facilitate the devel ....Use of Gas Expanded Liquids to Facilitate Process Intensification. The aim of this research is the utilisation of gas expanded liquids (GXLs) in technology platforms based on the principles of process intensification (PI). In order to facilitate the attainment of project objectives a comprehensive investigation of the fundamental properties of GXLs, and their interactions is proposed. A significant component of the programme is expected to be to use the knowledge obtained to facilitate the development of scale-up protocol for PI based methodologies, with particular emphasis on the production of biomaterials. GXLs technology is frontier technology with regard to the biomaterials sector.Read moreRead less
Designing Bandwidth-Efficient High-Speed Underwater Acoustic Communication Systems with Block-by-Block Turbo Processing. Australia has one of the largest exclusive economic zones in the world, and it is vitally important for Australia to understand and benefit from the oceans. This project will give new perspectives in developing underwater acoustic communications that are important for marine industries and scientific research in areas such as the exploration and exploitation of offshore oil an ....Designing Bandwidth-Efficient High-Speed Underwater Acoustic Communication Systems with Block-by-Block Turbo Processing. Australia has one of the largest exclusive economic zones in the world, and it is vitally important for Australia to understand and benefit from the oceans. This project will give new perspectives in developing underwater acoustic communications that are important for marine industries and scientific research in areas such as the exploration and exploitation of offshore oil and gas, and ocean environment and climate monitoring. This project will lift the international profile of Australia in underwater acoustic communications research and, through the training of early career researchers and PhD students, this project will also develop a skills base for Australia in underwater acoustic communications.Read moreRead less
The online future of Science and Engineering education: The essential elements of laboratory-based learning for remote-access implementation. Laboratory classes are a critical part of science and engineering degree programs, but there has been little research into what actually takes place within them. Remote laboratories, in which students control equipment via the internet, are one potential solution for accommodating rising numbers of students, but the interfaces must be developed to effectiv ....The online future of Science and Engineering education: The essential elements of laboratory-based learning for remote-access implementation. Laboratory classes are a critical part of science and engineering degree programs, but there has been little research into what actually takes place within them. Remote laboratories, in which students control equipment via the internet, are one potential solution for accommodating rising numbers of students, but the interfaces must be developed to effectively support student learning. This project will investigate how students interact with equipment, each other, and with laboratory demonstrators in order to determine the crucial components of effective laboratory learning experiences. It will identify and characterise the interactions of students in laboratory classes, and develop mechanisms to support these interactions remotely.Read moreRead less
Precision measurement to test fundamental physics. This project gives the University of Western Australia the opportunity to lead some of the world's best tests on fundamental physics by implementing their novel precision technology. It will also strengthen their collaboration between elite metrological institutes, including Paris Observatory, Ecole Normale Superior and Humboldt University.
Mitochondrial Retrograde Signalling in Plants – New Models and Analytical Approaches. Mitochondria are essential organelles involved in energy production and various metabolic and biosynthetic pathways in plant cells. Signals from mitochondria act to regulate nuclear gene expression to coordinate mitochondrial activity with cellular activity, which is called mitochondrial retrograde signalling (MRS). To date our knowledge of the pathways and components involved in MRS is limited to a single mode ....Mitochondrial Retrograde Signalling in Plants – New Models and Analytical Approaches. Mitochondria are essential organelles involved in energy production and various metabolic and biosynthetic pathways in plant cells. Signals from mitochondria act to regulate nuclear gene expression to coordinate mitochondrial activity with cellular activity, which is called mitochondrial retrograde signalling (MRS). To date our knowledge of the pathways and components involved in MRS is limited to a single model system. This proposal seeks to identify additional MRS pathways, characterise components of these pathways and the signals involved. This new knowledge can be used in translational research as a basis to breed plants with altered stress and growth properties.Read moreRead less
Building Better Brands: A Study of Australian Organizations and Consumers. The study is the first to be undertaken in the world to develop a knowledge management system of brand development and management. It focuses on understanding how branding strategies increase the competitiveness of Australian industry. The study also explores linkages of branding strategy to consumer perceptions of brand value. The model is firmly placed in a global market context, contrasting domestic, exported and im ....Building Better Brands: A Study of Australian Organizations and Consumers. The study is the first to be undertaken in the world to develop a knowledge management system of brand development and management. It focuses on understanding how branding strategies increase the competitiveness of Australian industry. The study also explores linkages of branding strategy to consumer perceptions of brand value. The model is firmly placed in a global market context, contrasting domestic, exported and imported brands. The focus is strongly orientated toward improving Australia's competitiveness and global performance. This study is vital as the economic superiority of strong nations is evident in the value and strength of their industries' brands.Read moreRead less
Bifurcation analysis with applications to design of power electronics systems. This project represents a fundamental study of nonlinear dynamics in power electronics systems. We expect that this project will result in knowledge advancement and technological innovations. In particular, rigorous algorithms will be resulted for the identification and analysis of nonlinear phenomena in power electronics systems. Special attention will be paid to design applications of power electronics systems. The ....Bifurcation analysis with applications to design of power electronics systems. This project represents a fundamental study of nonlinear dynamics in power electronics systems. We expect that this project will result in knowledge advancement and technological innovations. In particular, rigorous algorithms will be resulted for the identification and analysis of nonlinear phenomena in power electronics systems. Special attention will be paid to design applications of power electronics systems. The successful implementation of these methods and algorithms will definitely lead to development of frontier technology in engineering science, which is a National Priority Goal. Read moreRead less
Modelling network innovation performance capability: a multidisciplinary approach. Innovation is created in complex network interactions.
By combining agent-based and fuzzy logic modelling, this project will identify combinations of resources to generate new ideas/technologies. This will enable managers and policy makers to understand the mechanisms behind innovation and implement policies aimed at enhancing innovation processes.