Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a ....Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a red blood cell line. Simultaneously, this project aims to generate fundamental insights into mechanisms of human gene regulation. The technological and biological outcomes of this project will be of benefit for future gene editing applications.Read moreRead less
Elastic and biodegradable sponges/aerogels from exfoliated silk nanofibres . The aim of this project is to investigate methods to produce highly porous elastic sponges from silk protein nanofibres. These sponges will have optimal mechanical, insulation and degradation properties making them suitable for a wide range of applications including the biomedical and personal care sectors, where current products have significant drawbacks due to the use of non-biodegradable synthetic materials. Outco ....Elastic and biodegradable sponges/aerogels from exfoliated silk nanofibres . The aim of this project is to investigate methods to produce highly porous elastic sponges from silk protein nanofibres. These sponges will have optimal mechanical, insulation and degradation properties making them suitable for a wide range of applications including the biomedical and personal care sectors, where current products have significant drawbacks due to the use of non-biodegradable synthetic materials. Outcomes include new knowledge on controlling porous structures and tailoring properties to targeted applications. This project, by laying the groundwork for a new generation of bio-based materials, will benefit the Australian advanced manufacturing sector, and enhance Australia's standing in materials science and engineering.Read moreRead less
Coordinating Innovation in Knowledge-Based Multinational Organisations. Integration into global supply chains is one of the fundamental challenges for manufacturing companies in Australia. This project seeks to identify the optimal design for coordinating innovation in globally-dispersed organisations. It will analyse three mechanisms for transferring knowledge within organisations: hierarchies, communities of practice, and social networks. Outcomes will include a new multilevel statistical netw ....Coordinating Innovation in Knowledge-Based Multinational Organisations. Integration into global supply chains is one of the fundamental challenges for manufacturing companies in Australia. This project seeks to identify the optimal design for coordinating innovation in globally-dispersed organisations. It will analyse three mechanisms for transferring knowledge within organisations: hierarchies, communities of practice, and social networks. Outcomes will include a new multilevel statistical network modelling framework and organisational designs to overcome barriers to knowledge-transfer, such as language, culture and distance. The project will collect and apply data from Boeing Global Technology, the international research arm of The Boeing Company, a world leading business with major subsidiaries in Australia.Read moreRead less
Making eMaking Accessible for People with Intellectual Disabilities. This interdisciplinary research will create an evidence based eMaking program that empowers people with Intellectual Disabilities. eMaking benefits include collaborative problem solving and employment pathways; however, people with disabilities are often excluded. Through a unique, inclusive, outreach van, strategies to build accessible eMaking will be generated. Project outcomes include replicable, scalable eMaking activities ....Making eMaking Accessible for People with Intellectual Disabilities. This interdisciplinary research will create an evidence based eMaking program that empowers people with Intellectual Disabilities. eMaking benefits include collaborative problem solving and employment pathways; however, people with disabilities are often excluded. Through a unique, inclusive, outreach van, strategies to build accessible eMaking will be generated. Project outcomes include replicable, scalable eMaking activities and toolkits to facilitate Science, Technology, Engineering and Mathematics for all. Project benefits include opportunities for people with Intellectual Disability to participate in meaningful recreational or work-focused eMaking, and changing community attitudes through shared eMaking participation.Read moreRead less
Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing ....Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing systems that will better protect wearers and allow them to effectively combat bushfires and save lives and assets. The successful completion will enable industrial capability in next generation advanced protective garments and functional uniforms for broad occupational health safety and well-being applications.Read moreRead less
Advancing digital inclusion in low income Australian families. This ethnographic investigation explores the complex relationship between digital and social inclusion, and social infrastructure's role (education facilities, charities, government services) in supporting low-income families' social and economic participation. It gathers insights from families in six diverse communities from Far North Queensland to Tasmania, across diverse urban, regional and rural locations. It focuses on the digit ....Advancing digital inclusion in low income Australian families. This ethnographic investigation explores the complex relationship between digital and social inclusion, and social infrastructure's role (education facilities, charities, government services) in supporting low-income families' social and economic participation. It gathers insights from families in six diverse communities from Far North Queensland to Tasmania, across diverse urban, regional and rural locations. It focuses on the digital inclusion implications of children's home and school learning experiences, school leavers' transitions into work, and parenting in digital times. The project is a collaboration with Australia's leading digital inclusion organisations and will develop new practices, policies and sector wide solutions.Read moreRead less
Net Zero Precincts: an interdisciplinary approach to decarbonising cities. This project aims to help cities and urban regions reach net zero emissions by taking the precinct as an optimal scale for urban transition. This project expects to co-create a new approach grounded in transition management and design anthropology. This will be tested in an action-oriented case study in the Monash Technology Precinct through three Living Lab experiments across energy, mobility and buildings. Expected outc ....Net Zero Precincts: an interdisciplinary approach to decarbonising cities. This project aims to help cities and urban regions reach net zero emissions by taking the precinct as an optimal scale for urban transition. This project expects to co-create a new approach grounded in transition management and design anthropology. This will be tested in an action-oriented case study in the Monash Technology Precinct through three Living Lab experiments across energy, mobility and buildings. Expected outcomes include a validated approach for net zero transitions that delivers to the real-life experiences of the precinct community of business, government, knowledge institutes and civil society. This should provide significant benefits to industry seeking to enhance community engagement for accelerating urban transitions.
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Diamond-based wideband radiofrequency fibre-optic sensor. This project aims to address the growing problem of ultra-wide radiofrequency signal monitoring. Developing a rugged and portable solution for whole-spectrum monitoring is a critical unmet need for Defence and other industries, and an important scientific challenge. Our approach is based on a diamond radio frequency sensor with fibre-optic readout. The project is expected to generate knowledge in the areas of quantum science and photonics ....Diamond-based wideband radiofrequency fibre-optic sensor. This project aims to address the growing problem of ultra-wide radiofrequency signal monitoring. Developing a rugged and portable solution for whole-spectrum monitoring is a critical unmet need for Defence and other industries, and an important scientific challenge. Our approach is based on a diamond radio frequency sensor with fibre-optic readout. The project is expected to generate knowledge in the areas of quantum science and photonics by integrating advanced optical fibres with quantum-grade diamond. Expected outcomes of the project include the development of a strategic academic and industry alliance through the establishment of a sovereign capability that will benefit Australia in the areas of cybersecurity and advanced manufacturing.Read moreRead less
Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost a ....Wideband Silicon-Based Radio-Frequency Front-End Module for 5G New Radio . The project aims to advance knowledge in radio-frequency integrated circuit design in low-cost silicon technologies, particularly power amplifiers design with enhanced energy efficiency at output power back-off levels. The intended outcome of this project will be a wideband RF front-end module with beam steering capability that can cover the 24-50 GHz spectrum band. This will ultimately enable the creation of a low-cost and energy-efficient 5G millimetre-wave network that could potentially trigger the development of ultra-reliable low latency communications, which is critical for emerging intelligent transportation systems and will maintain Australia’s leadership position in the development of break-through wireless technology.Read moreRead less
Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter wi ....Low-Cost Wireless Transmitter with Compact Package for Industrial Sensing . This project aims to provide a solid foundation for silicon-based transmitter design with beam-steering capability operating beyond 100 GHz. The project expects to advance knowledge in low-cost radio-frequency integrated circuit design with miniaturised packaging technology for use in industrial sensing. Expected outcomes of this project include a prototype consisting of a miniaturised 140-GHz phased-array transmitter with packaged antenna arrays, along with a developed selection guideline to choose the "best" silicon-based technology node for cost-effective design. This should provide benefits for organisations working on wireless sensing technologies and lead to new ways of using these technologies for a variety of emerging applications.Read moreRead less