Synthetic regulators of gene expression. RNA plays many essential roles in cells, from information transfer and regulation of gene expression to scaffolding macromolecular structures and catalysis. Despite these realisations the current approaches to manipulate RNA are limited in many respects. This project will use synthetic biology approaches to engineer synthetic regulators of RNAs in living cells. These studies will provide new tools for use in biological research and provide insights into h ....Synthetic regulators of gene expression. RNA plays many essential roles in cells, from information transfer and regulation of gene expression to scaffolding macromolecular structures and catalysis. Despite these realisations the current approaches to manipulate RNA are limited in many respects. This project will use synthetic biology approaches to engineer synthetic regulators of RNAs in living cells. These studies will provide new tools for use in biological research and provide insights into how natural proteins control gene expression. Furthermore, this project will use these tools to understand the mechanisms of how proteins are synthesised in mammalian mitochondria.Read moreRead less
Chemical signalling in the sea. This project aims to understand how eggs attract and select sperm, and how the environment influences these interactions. Differential sperm chemotaxis, a form of mate choice involving chemical signalling between eggs and sperm, has only been described in mussels, but may be a widespread form of gamete-level sexual selection. The project will study the biochemical and molecular basis of differential sperm chemotaxis in mussels, and the stability of gamete-level in ....Chemical signalling in the sea. This project aims to understand how eggs attract and select sperm, and how the environment influences these interactions. Differential sperm chemotaxis, a form of mate choice involving chemical signalling between eggs and sperm, has only been described in mussels, but may be a widespread form of gamete-level sexual selection. The project will study the biochemical and molecular basis of differential sperm chemotaxis in mussels, and the stability of gamete-level interactions under different environmental conditions. Improved fundamental knowledge of reproduction in a commercially important marine species may yield future commercial benefits for Australia’s marine food production sectorRead moreRead less
Use of Gas Expanded Liquids to Facilitate Process Intensification. The aim of this research is the utilisation of gas expanded liquids (GXLs) in technology platforms based on the principles of process intensification (PI). In order to facilitate the attainment of project objectives a comprehensive investigation of the fundamental properties of GXLs, and their interactions is proposed. A significant component of the programme is expected to be to use the knowledge obtained to facilitate the devel ....Use of Gas Expanded Liquids to Facilitate Process Intensification. The aim of this research is the utilisation of gas expanded liquids (GXLs) in technology platforms based on the principles of process intensification (PI). In order to facilitate the attainment of project objectives a comprehensive investigation of the fundamental properties of GXLs, and their interactions is proposed. A significant component of the programme is expected to be to use the knowledge obtained to facilitate the development of scale-up protocol for PI based methodologies, with particular emphasis on the production of biomaterials. GXLs technology is frontier technology with regard to the biomaterials sector.Read moreRead less
Extending Leadership and Learning: Improving the effectiveness of new learning technology for culture change and improved regional business performance. This research project explores the complex relationships between new technology and learning, and the subsequent impact on organisational change and business effectiveness. The study will examine the use of video-conferencing and on-line training packages in the regional locations of a major bank, in order to determine more effective configurati ....Extending Leadership and Learning: Improving the effectiveness of new learning technology for culture change and improved regional business performance. This research project explores the complex relationships between new technology and learning, and the subsequent impact on organisational change and business effectiveness. The study will examine the use of video-conferencing and on-line training packages in the regional locations of a major bank, in order to determine more effective configurations of learning architecture that support organisational culture change and impact on business performance. The organisation has a strategic commitment to cultural change towards leadership and learning. This research intends to examine how new learning technologies can more effectively impact on achieving such cultural change and improved regional equity.Read moreRead less
Designing Bandwidth-Efficient High-Speed Underwater Acoustic Communication Systems with Block-by-Block Turbo Processing. Australia has one of the largest exclusive economic zones in the world, and it is vitally important for Australia to understand and benefit from the oceans. This project will give new perspectives in developing underwater acoustic communications that are important for marine industries and scientific research in areas such as the exploration and exploitation of offshore oil an ....Designing Bandwidth-Efficient High-Speed Underwater Acoustic Communication Systems with Block-by-Block Turbo Processing. Australia has one of the largest exclusive economic zones in the world, and it is vitally important for Australia to understand and benefit from the oceans. This project will give new perspectives in developing underwater acoustic communications that are important for marine industries and scientific research in areas such as the exploration and exploitation of offshore oil and gas, and ocean environment and climate monitoring. This project will lift the international profile of Australia in underwater acoustic communications research and, through the training of early career researchers and PhD students, this project will also develop a skills base for Australia in underwater acoustic communications.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH130200025
Funder
Australian Research Council
Funding Amount
$2,181,756.00
Summary
ARC Research Hub for transforming waste directly in cost-effective green manufacturing. ARC Research Hub for transforming waste directly in cost-effective green manufacturing. This Research Hub aims to create a unique opportunity for completely different industries to come together, with a common goal of creating value from mixed plastic and glass waste in manufacturing. Starting with fundamental investigations of the transformation behaviour of waste materials under high temperature conditions, ....ARC Research Hub for transforming waste directly in cost-effective green manufacturing. ARC Research Hub for transforming waste directly in cost-effective green manufacturing. This Research Hub aims to create a unique opportunity for completely different industries to come together, with a common goal of creating value from mixed plastic and glass waste in manufacturing. Starting with fundamental investigations of the transformation behaviour of waste materials under high temperature conditions, the hub will focus on developing scalable solutions for its manufacturing partners towards reducing the consumption of primary resources while simultaneously diverting waste streams from landfill. Additionally, the potential of using such transformations to yield improved products such as wear-resistant grinding media and light-weight building materials will be investigated to enhance Australian manufacturing.Read moreRead less
Control points in nitrogen uptake: enhancing the response of cereals to nitrogen supply and demand. Vast amounts of nitrogen fertiliser are applied to cereal crops to maintain yields. By uncovering what limits nitrogen uptake in cereals, this project will provide the scientific basis for improving nitrogen use efficiency and decreasing fertiliser use, with significant economic and environmental benefits.
The online future of Science and Engineering education: The essential elements of laboratory-based learning for remote-access implementation. Laboratory classes are a critical part of science and engineering degree programs, but there has been little research into what actually takes place within them. Remote laboratories, in which students control equipment via the internet, are one potential solution for accommodating rising numbers of students, but the interfaces must be developed to effectiv ....The online future of Science and Engineering education: The essential elements of laboratory-based learning for remote-access implementation. Laboratory classes are a critical part of science and engineering degree programs, but there has been little research into what actually takes place within them. Remote laboratories, in which students control equipment via the internet, are one potential solution for accommodating rising numbers of students, but the interfaces must be developed to effectively support student learning. This project will investigate how students interact with equipment, each other, and with laboratory demonstrators in order to determine the crucial components of effective laboratory learning experiences. It will identify and characterise the interactions of students in laboratory classes, and develop mechanisms to support these interactions remotely.Read moreRead less
Physiology and genetics of barley grain germination in the malting and brewing industries. An international research team will provide new scientific information on barley grain germination. This detailed basic knowledge will be immediately applied in breeding programs that are aimed at improving malting and brewing quality in a commercial context. At the same time, the industry's carbon footprint will be significantly reduced.
Discovery Early Career Researcher Award - Grant ID: DE140100320
Funder
Australian Research Council
Funding Amount
$394,371.00
Summary
Understanding cone photoreceptor migration and cell death mechanisms . Normal vision requires functional and correctly located cone photoreceptor cells. Many genetic mutations, however, impair the correct migration of these cells during development and ultimately cause cell death. This project will investigate, for the first time, the casual link between the migration of cone cells and activation of cell death mechanisms. A coordinated approach, using a range of molecular techniques, will be use ....Understanding cone photoreceptor migration and cell death mechanisms . Normal vision requires functional and correctly located cone photoreceptor cells. Many genetic mutations, however, impair the correct migration of these cells during development and ultimately cause cell death. This project will investigate, for the first time, the casual link between the migration of cone cells and activation of cell death mechanisms. A coordinated approach, using a range of molecular techniques, will be used to determine which factors are essential for normal development, correct spatial location and survival of cone photoreceptors within the mammalian retina. This will provide a major step forward in our knowledge of the processes involved in the spatial deployment of cones and the developmental organisation of the retina.Read moreRead less