Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a ....Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a red blood cell line. Simultaneously, this project aims to generate fundamental insights into mechanisms of human gene regulation. The technological and biological outcomes of this project will be of benefit for future gene editing applications.Read moreRead less
Development of biosensors and bioindicators for gold exploration and processing in Australia. In times of increasing demand for gold and shrinking rates of discovery in Australia, biosensor and bioindicator techniques deliver significant advantages to the Australian mining industry and allow it to retain its international competiveness. The new understanding of the biogeochemical behaviour of gold in soils and other weathered materials developed in a previous ARC Linkage Project enables the deve ....Development of biosensors and bioindicators for gold exploration and processing in Australia. In times of increasing demand for gold and shrinking rates of discovery in Australia, biosensor and bioindicator techniques deliver significant advantages to the Australian mining industry and allow it to retain its international competiveness. The new understanding of the biogeochemical behaviour of gold in soils and other weathered materials developed in a previous ARC Linkage Project enables the development of biosensor and bioindicator technology that will allow mineral explorers to differentiate mineralised from non-mineralised zones using specific (meta) genomic community responses. The new technology will provide cost-efficient and environmentally sustainable techniques for improving exploration success and optimising ore processing.Read moreRead less
From genotype to phenotype: Molecular photofitting for criminal investigations. DNA found at crime scenes has the potential to provide a physical description of the donor in the same way as an eyewitness statement can be used to make a facial reconstruction. This project will investigate those physical traits which can be derived from the analysis of DNA present in samples collected in relation to criminal activities.
Integration of Wireless LAN and GPRS/UMTS Cellular Systems. Integration of wireless local area networks with cellular mobile systems provides a feasible, reliable, and cost-effective way for high-speed mobile Internet access in wide area networks. In this project in collaboration with Australia's second largest telecommunications company; Optus, we will develop network architecture and essential access and mobility techniques for such a system. The project's outcomes will enable Optus to expand ....Integration of Wireless LAN and GPRS/UMTS Cellular Systems. Integration of wireless local area networks with cellular mobile systems provides a feasible, reliable, and cost-effective way for high-speed mobile Internet access in wide area networks. In this project in collaboration with Australia's second largest telecommunications company; Optus, we will develop network architecture and essential access and mobility techniques for such a system. The project's outcomes will enable Optus to expand its broadband mobile Internet service to all parts and population of the country including rural and regional areas and subsequently export the breakthrough technology resulted from the project to overseas.Read moreRead less
Cooperative Mesh Networks for Municipal Wireless Access. Robust mobile broadband data communication is vital for public safety and emergency services applications. This project will improve the performance and cost-effectiveness of mesh networks, enabling new network architectures. Immediate benefits to Australia will be: Contribution to a growing knowledge base and fundamental capabilities wireless broadband communications; Education of future leading academic and industrial innovators; Raising ....Cooperative Mesh Networks for Municipal Wireless Access. Robust mobile broadband data communication is vital for public safety and emergency services applications. This project will improve the performance and cost-effectiveness of mesh networks, enabling new network architectures. Immediate benefits to Australia will be: Contribution to a growing knowledge base and fundamental capabilities wireless broadband communications; Education of future leading academic and industrial innovators; Raising the international profile of Australian research in information technology. The contribution of Information and Communications Technology to the National economy is widely recognized. ICT contributes to wealth creation, employment and exports, underpinning many innovation processes.Read moreRead less
Translating genomic discoveries into improved commercial outcomes for the South Sea pearl industry. The purpose of this project is to understand the relationship between gene expression and pearl quality. By identifying the relationship between genes and pearls this project will determine the best conditions to grow selected pearl oyster stocks for the Australian South Sea pearl industry.
Enhancing Australian Universities' Research Commercialisation Performance. The primary aims of the project are to develop a detailed understanding of the systematic barriers to research commercialisation within Australian universities and to promote innovation within the commercialisation through the adoption of effective processes. The project will also explore the needs of the smaller and regional universities to develop effective strategies that will enhance their research commercialisation c ....Enhancing Australian Universities' Research Commercialisation Performance. The primary aims of the project are to develop a detailed understanding of the systematic barriers to research commercialisation within Australian universities and to promote innovation within the commercialisation through the adoption of effective processes. The project will also explore the needs of the smaller and regional universities to develop effective strategies that will enhance their research commercialisation capacity and performance through the promotion of industry uptake of their research outcomes.Read moreRead less
Improving road safety: advanced hybrid vehicle-based technology for monitoring driver drowsiness. Innovative technology geared towards reducing road accidents and fatalities (for improving public health) will constitute major socio-economic benefit to Australia. The Australian Transport Safety Bureau notes fatigue as a major cause of road accidents (2006). The World Health Organisation dedicated World Health Day 2004 to road safety and emphasized the importance of combating fatigue ('Road Safety ....Improving road safety: advanced hybrid vehicle-based technology for monitoring driver drowsiness. Innovative technology geared towards reducing road accidents and fatalities (for improving public health) will constitute major socio-economic benefit to Australia. The Australian Transport Safety Bureau notes fatigue as a major cause of road accidents (2006). The World Health Organisation dedicated World Health Day 2004 to road safety and emphasized the importance of combating fatigue ('Road Safety is no Accident'). This research will develop an innovative driver drowsiness detecting technology. With drowsiness attributable to substantial road fatalities, this technology aims to reduce this emotional and socio-economic burden on the community, contributing to national and community benefit by providing a safer road environment.Read moreRead less
Smart Antennas for Broadband Wireless Data Systems. Smart antennas can facilitate accommodation of an increasing demand for bandwidth and quality in wireless communications by directing the antenna beam towards the desired user, while suppressing signals coming from interferers. The beam forming processor can adapt to changes in channel propagation conditions as well as movements of the user or interferers. Many algorithms for controlling smart antennas have been proposed, and usually there is a ....Smart Antennas for Broadband Wireless Data Systems. Smart antennas can facilitate accommodation of an increasing demand for bandwidth and quality in wireless communications by directing the antenna beam towards the desired user, while suppressing signals coming from interferers. The beam forming processor can adapt to changes in channel propagation conditions as well as movements of the user or interferers. Many algorithms for controlling smart antennas have been proposed, and usually there is a trade-off between complexity and performance. We aim to find a suitable compromise to implement smart antennas for broadband wireless access systems and to apply smart antenna technology to increase the range of ultra-wideband communications.Read moreRead less
A cross-national comparison of novel market-pull technology transfer programs which facilitate research organisation commercialisation through dynamic SMEs. This research will contribute to a more competitive and innovative economy in two ways. First it will provide a basis for improved public policy to stimulate technology uptake by small business, which is critical for small business growth and innovation. Second, it will identify innovative policies to facilitate the uptake of university rese ....A cross-national comparison of novel market-pull technology transfer programs which facilitate research organisation commercialisation through dynamic SMEs. This research will contribute to a more competitive and innovative economy in two ways. First it will provide a basis for improved public policy to stimulate technology uptake by small business, which is critical for small business growth and innovation. Second, it will identify innovative policies to facilitate the uptake of university research, to enhance the contribution of universities to the economy. The proposed research is original because it focuses on the way in which the technology needs of small firms can be met by existing university knowledge and technologies. Prior research on technology transfer focuses on pushing university research out to industry through university spin-offs or university and large firm linkages.Read moreRead less