Elastic and biodegradable sponges/aerogels from exfoliated silk nanofibres . The aim of this project is to investigate methods to produce highly porous elastic sponges from silk protein nanofibres. These sponges will have optimal mechanical, insulation and degradation properties making them suitable for a wide range of applications including the biomedical and personal care sectors, where current products have significant drawbacks due to the use of non-biodegradable synthetic materials. Outco ....Elastic and biodegradable sponges/aerogels from exfoliated silk nanofibres . The aim of this project is to investigate methods to produce highly porous elastic sponges from silk protein nanofibres. These sponges will have optimal mechanical, insulation and degradation properties making them suitable for a wide range of applications including the biomedical and personal care sectors, where current products have significant drawbacks due to the use of non-biodegradable synthetic materials. Outcomes include new knowledge on controlling porous structures and tailoring properties to targeted applications. This project, by laying the groundwork for a new generation of bio-based materials, will benefit the Australian advanced manufacturing sector, and enhance Australia's standing in materials science and engineering.Read moreRead less
Investigations into the antibacterial mechanism of action of cannabidiol. This project aims to understand how the compound cannabidiol is able to kill bacteria by examining its interactions with bacteria from a genetic and molecular level. This research is critical, because future development of cannabidiol and design of improved analogs is predicated on knowing how it works. Expected outcomes include the first detailed understanding of how cannabidiol interacts with bacteria. This should lead ....Investigations into the antibacterial mechanism of action of cannabidiol. This project aims to understand how the compound cannabidiol is able to kill bacteria by examining its interactions with bacteria from a genetic and molecular level. This research is critical, because future development of cannabidiol and design of improved analogs is predicated on knowing how it works. Expected outcomes include the first detailed understanding of how cannabidiol interacts with bacteria. This should lead to significant benefits, including high impact publications, additional collaborations with industrial partner Botanix, and a new class of antibiotics to overcome antibiotic resistance.Read moreRead less
Extending Leadership and Learning: Improving the effectiveness of new learning technology for culture change and improved regional business performance. This research project explores the complex relationships between new technology and learning, and the subsequent impact on organisational change and business effectiveness. The study will examine the use of video-conferencing and on-line training packages in the regional locations of a major bank, in order to determine more effective configurati ....Extending Leadership and Learning: Improving the effectiveness of new learning technology for culture change and improved regional business performance. This research project explores the complex relationships between new technology and learning, and the subsequent impact on organisational change and business effectiveness. The study will examine the use of video-conferencing and on-line training packages in the regional locations of a major bank, in order to determine more effective configurations of learning architecture that support organisational culture change and impact on business performance. The organisation has a strategic commitment to cultural change towards leadership and learning. This research intends to examine how new learning technologies can more effectively impact on achieving such cultural change and improved regional equity.Read moreRead less
Control points in nitrogen uptake: enhancing the response of cereals to nitrogen supply and demand. Vast amounts of nitrogen fertiliser are applied to cereal crops to maintain yields. By uncovering what limits nitrogen uptake in cereals, this project will provide the scientific basis for improving nitrogen use efficiency and decreasing fertiliser use, with significant economic and environmental benefits.
Physiology and genetics of barley grain germination in the malting and brewing industries. An international research team will provide new scientific information on barley grain germination. This detailed basic knowledge will be immediately applied in breeding programs that are aimed at improving malting and brewing quality in a commercial context. At the same time, the industry's carbon footprint will be significantly reduced.
Towards the health care system of the future: The role of institutional entrepreneurship in service redesign and innovation. The reform of healthcare systems presents one of the most pressing and fundamental challenges for nations such as Australia. To date, hospital redesign and innovation initiatives have had limited impacts and outcomes at a system level with improvements limited to discrete areas. The aim of this inter-disciplinary research is to promote the scaling up of such initiatives to ....Towards the health care system of the future: The role of institutional entrepreneurship in service redesign and innovation. The reform of healthcare systems presents one of the most pressing and fundamental challenges for nations such as Australia. To date, hospital redesign and innovation initiatives have had limited impacts and outcomes at a system level with improvements limited to discrete areas. The aim of this inter-disciplinary research is to promote the scaling up of such initiatives to have systems-wide outcomes. The research aims to address institutional constraints and organisational factors and will develop practical frameworks, processes and resources. These intend to enable hospitals to develop organisational and leadership capacities to ensure investments in redesign and innovation have ‘whole system’ economic and healthcare benefits.Read moreRead less
Hybrid radiofrequency/optical catheter for effective atrial fibrillation ablation. This research project aims to advance engineering knowledge by applying an innovative, fibre-optics-based discrete optical coherence tomography to technology used for atrial fibrillation catheter ablation. RadioFrequency catheter-based ablation is far superior to cardiac drug therapy for atrial fibrillation patients. RadioFrequency catheters are not equipped with real-time lesion formation monitoring means, which ....Hybrid radiofrequency/optical catheter for effective atrial fibrillation ablation. This research project aims to advance engineering knowledge by applying an innovative, fibre-optics-based discrete optical coherence tomography to technology used for atrial fibrillation catheter ablation. RadioFrequency catheter-based ablation is far superior to cardiac drug therapy for atrial fibrillation patients. RadioFrequency catheters are not equipped with real-time lesion formation monitoring means, which enable the assessment of continuity-transmurality and prevent extra-cardiac complications, such as steam pops. Optical Coherece Tomography enables non-invasive, microscopic lesion formation assessment in real time during atrial fibrillation ablation procedures. The expected outcomes of this project are to develop a new hybrid fibre-optic/RadioFrequency catheter system and user-friendly driving software that will enable cardiac electrophysiologists to perform three key tasks not previously available.Read moreRead less
Learning Mechanisms and the Development of Dynamic Capabilities within Firms. The project has the following national/community benefits: (1) a more comprehensive study of the specific and unique features of the structure and innovative process operating within a major Australian producer of commodities, (2) a greater understanding of how knowledge can be created and captured in the form of firm-level dynamic capabilities, contributing towards the creation of an effective knowledge and innovation ....Learning Mechanisms and the Development of Dynamic Capabilities within Firms. The project has the following national/community benefits: (1) a more comprehensive study of the specific and unique features of the structure and innovative process operating within a major Australian producer of commodities, (2) a greater understanding of how knowledge can be created and captured in the form of firm-level dynamic capabilities, contributing towards the creation of an effective knowledge and innovation economy, and (3) assisting regional communities by providing specific recommendations for generating learning mechanisms and more importantly, capturing value from learning in terms of process improvement and innovation.Read moreRead less
Net Zero Precincts: an interdisciplinary approach to decarbonising cities. This project aims to help cities and urban regions reach net zero emissions by taking the precinct as an optimal scale for urban transition. This project expects to co-create a new approach grounded in transition management and design anthropology. This will be tested in an action-oriented case study in the Monash Technology Precinct through three Living Lab experiments across energy, mobility and buildings. Expected outc ....Net Zero Precincts: an interdisciplinary approach to decarbonising cities. This project aims to help cities and urban regions reach net zero emissions by taking the precinct as an optimal scale for urban transition. This project expects to co-create a new approach grounded in transition management and design anthropology. This will be tested in an action-oriented case study in the Monash Technology Precinct through three Living Lab experiments across energy, mobility and buildings. Expected outcomes include a validated approach for net zero transitions that delivers to the real-life experiences of the precinct community of business, government, knowledge institutes and civil society. This should provide significant benefits to industry seeking to enhance community engagement for accelerating urban transitions.
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Fertility crisis: harnessing the genomic tension behind pollen fertility in sorghum. Hybrid sorghum varieties yield more grain than inbred varieties but the production seed for farmers can be difficult. This project will identify the genes responsible for a trait that makes hybrid seed production possible and this knowledge will help raise sorghum yields in Australian and in some of the world’s poorest countries.