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Status : Active
Field of Research : Numerical Analysis
Research Topic : Microarray analysis
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  • Researchers (53)
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  • Active Funded Activity

    Discovery Projects - Grant ID: DP220102243

    Funder
    Australian Research Council
    Funding Amount
    $420,000.00
    Summary
    Advanced Bayesian Inversion Algorithms for Wave Propagation. This project aims to improve algorithms for detecting hidden items by developing new computational mathematical techniques capable of reconstructing the shape and location of objects using electromagnetic waves. This project expects to generate new knowledge in the areas of Bayesian Inversion and computational wave propagation. Expected outcomes of this project are algorithms that can be developed for use in nonintrusive radio wave sec .... Advanced Bayesian Inversion Algorithms for Wave Propagation. This project aims to improve algorithms for detecting hidden items by developing new computational mathematical techniques capable of reconstructing the shape and location of objects using electromagnetic waves. This project expects to generate new knowledge in the areas of Bayesian Inversion and computational wave propagation. Expected outcomes of this project are algorithms that can be developed for use in nonintrusive radio wave security scanners. This should provide benefits such as the capability to scan a crowd without a checkpoint, which will have the potential to improve security in public places.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP180100506

    Funder
    Australian Research Council
    Funding Amount
    $386,828.00
    Summary
    Uncertainty on spheres and shells: mathematics and methods for applications. This project aims to develop new mathematics and mathematically rigorous approximation methods for physical problems on spherical geometries in the presence of uncertainty. Many physical phenomena are modelled on either a sphere or a spherical shell. Such models typically have large uncertainty in the input data, through uncertainty in model coefficients, forcing terms, geometry or boundary conditions. Yet their stochas .... Uncertainty on spheres and shells: mathematics and methods for applications. This project aims to develop new mathematics and mathematically rigorous approximation methods for physical problems on spherical geometries in the presence of uncertainty. Many physical phenomena are modelled on either a sphere or a spherical shell. Such models typically have large uncertainty in the input data, through uncertainty in model coefficients, forcing terms, geometry or boundary conditions. Yet their stochastic modelling and subsequent numerical analysis in the presence of uncertainty are still in their infancy. This project will conduct numerical analysis, stochastic analysis and approximation to address such problems.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP220100937

    Funder
    Australian Research Council
    Funding Amount
    $394,000.00
    Summary
    A new numerical analysis for partial differential equations with noise. This project aims to design novel numerical methods, grounded in rigorous mathematical foundations, for partial differential equations with stochastic source terms, such as for instance those modelling fluid flows with random perturbations. To ensure the accuracy of numerical simulations, preserving certain quantities of importance (mass, flux) is critical. The project's goal is to develop finite volume and high-order numeri .... A new numerical analysis for partial differential equations with noise. This project aims to design novel numerical methods, grounded in rigorous mathematical foundations, for partial differential equations with stochastic source terms, such as for instance those modelling fluid flows with random perturbations. To ensure the accuracy of numerical simulations, preserving certain quantities of importance (mass, flux) is critical. The project's goal is to develop finite volume and high-order numerical methods that are applicable in real-world settings, designed to achieve this preservation of essential quantities, and mathematically proven to be robust. The expected benefits are cost-efficient and reliable numerical tools for the scientific simulation of phenomena subjected to uncontrolled influence.
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    Active Funded Activity

    ARC Future Fellowships - Grant ID: FT170100231

    Funder
    Australian Research Council
    Funding Amount
    $800,000.00
    Summary
    Regularisation methods of inverse problems: theory and computation. This project aims to investigate regularisation methods for inverse problems which are ill-posed in the sense that their solutions depend discontinuously on the data. When only noisy data is available, regularisation methods define stable approximate solutions by replacing the original inverse problem with a family of well-posed neighbouring problems monitored by a so-called regularisation parameter. The project expects to devel .... Regularisation methods of inverse problems: theory and computation. This project aims to investigate regularisation methods for inverse problems which are ill-posed in the sense that their solutions depend discontinuously on the data. When only noisy data is available, regularisation methods define stable approximate solutions by replacing the original inverse problem with a family of well-posed neighbouring problems monitored by a so-called regularisation parameter. The project expects to develop purely data-driven rules to choose the regularisation parameter and show how they work in theory, and in practice. It will also develop convex framework, acceleration strategies as well as preconditioning and splitting ideas to design efficient regularisation solvers.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP210103092

    Funder
    Australian Research Council
    Funding Amount
    $475,000.00
    Summary
    Interface-aware numerical methods for stochastic inverse problems. This project aims to design novel high-performance numerical tools for solving large-scale forward and inverse problems dominated by stochastic interfaces and quantifying associated uncertainties. In real-world applications such as groundwater, these tools are instrumental for assimilating big datasets into mathematical models for providing reliable predictions. By advancing and integrating high-order polytopal schemes, multileve .... Interface-aware numerical methods for stochastic inverse problems. This project aims to design novel high-performance numerical tools for solving large-scale forward and inverse problems dominated by stochastic interfaces and quantifying associated uncertainties. In real-world applications such as groundwater, these tools are instrumental for assimilating big datasets into mathematical models for providing reliable predictions. By advancing and integrating high-order polytopal schemes, multilevel methods, transport maps, and dimension reduction, this project's anticipated outcomes are highly accurate and cost-efficient numerical schemes, certified by rigorous mathematical analysis. This should provide data-centric simulation tools with enhanced reliability, for engineering and scientific applications.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP220103160

    Funder
    Australian Research Council
    Funding Amount
    $396,000.00
    Summary
    Towards predictive 4D computational models for the heart. This project aims to develop novel high-performance numerical algorithms for multiscale and multiphysics PDEs with dynamic interfaces, the development and analysis of a novel PDE system modelling the electromechanics of heart and torso, and the combination of these numerical techniques and models to deliver predictive tools for patient-specific simulations of the cardiac function. It involves the design and mathematical analysis of space- .... Towards predictive 4D computational models for the heart. This project aims to develop novel high-performance numerical algorithms for multiscale and multiphysics PDEs with dynamic interfaces, the development and analysis of a novel PDE system modelling the electromechanics of heart and torso, and the combination of these numerical techniques and models to deliver predictive tools for patient-specific simulations of the cardiac function. It involves the design and mathematical analysis of space-time variational discretisations on embedded meshes, 4D computational geometry algorithms for numerical integration and multilevel solvers. By combining scientific computing and machine learning, one anticipated outcome of this research is a new generation of nonlinear PDE approximations and solvers.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP190101889

    Funder
    Australian Research Council
    Funding Amount
    $339,000.00
    Summary
    Fractional dynamic models for MRI to probe tissue microstructure. This project aims to develop new mathematical tools for mapping tissue microstructural properties via the use of space-time fractional calculus methods. In magnetic resonance imaging, mathematical models and their parameters play a key role in associating information between images and biology, with the overall aim of producing spatially resolved maps of tissue property variations. However, models which can inform on changes in mi .... Fractional dynamic models for MRI to probe tissue microstructure. This project aims to develop new mathematical tools for mapping tissue microstructural properties via the use of space-time fractional calculus methods. In magnetic resonance imaging, mathematical models and their parameters play a key role in associating information between images and biology, with the overall aim of producing spatially resolved maps of tissue property variations. However, models which can inform on changes in microscale tissue properties are lacking. The tools developed by this project will be used to generate new magnetic resonance image based maps to convey information on tissue microstructure changes in the human brain. Additionally, the mathematical tools developed will be transferable to other applications where diffusion and transport in heterogeneous porous media play a role.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP210100831

    Funder
    Australian Research Council
    Funding Amount
    $630,000.00
    Summary
    High Dimensional Computation and Uncertainty. This project aims to establish powerful computational methods for high-dimensional problems - methods that are rigorous, and carefully tailored to specific applications, from physics, environment, manufacturing and finance, and often driven by uncertainty. The project will generate new knowledge in the area of high-dimensional computation, and develop technological innovations in key areas of science and industry. Expected outcomes include improved c .... High Dimensional Computation and Uncertainty. This project aims to establish powerful computational methods for high-dimensional problems - methods that are rigorous, and carefully tailored to specific applications, from physics, environment, manufacturing and finance, and often driven by uncertainty. The project will generate new knowledge in the area of high-dimensional computation, and develop technological innovations in key areas of science and industry. Expected outcomes include improved control of uncertainty in industry, enhanced international and interdisciplinary collaborations, and significant publications and presentations in international forums. The technological advancements will help boost Australia's position as a world leader in innovation.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP220101811

    Funder
    Australian Research Council
    Funding Amount
    $412,000.00
    Summary
    Novel Mathematics and Efficient Computational Techniques for Human Vision. This project aims to develop a new mathematical framework to understand elastic properties of human corneas. The project expects to generate new knowledge in understanding bio-mechanical models for human corneas, as well as other engineering applications involving materials with random fluctuations of elasticity. Expected outcomes of this project include new mathematics and computational algorithms for solving complex mat .... Novel Mathematics and Efficient Computational Techniques for Human Vision. This project aims to develop a new mathematical framework to understand elastic properties of human corneas. The project expects to generate new knowledge in understanding bio-mechanical models for human corneas, as well as other engineering applications involving materials with random fluctuations of elasticity. Expected outcomes of this project include new mathematics and computational algorithms for solving complex mathematical equations which describe elastic and hyper-elastic materials such as human corneas. This project will benefit Australia by enhancing the standing in cutting edge research trends in computational mathematics such as uncertainty quantification and machine learning.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP220103156

    Funder
    Australian Research Council
    Funding Amount
    $375,000.00
    Summary
    Multiscale modelling of systems with complex microscale detail. In modern science and engineering many complex systems are described by distinctly different microscale physical models within different regions of space. This project is to develop systematic mathematical and computational methods for the compact and accurate macroscale modelling and computation of such systems for application in industrial research and development. Our sparse simulations, justified with mathematical analysis, use .... Multiscale modelling of systems with complex microscale detail. In modern science and engineering many complex systems are described by distinctly different microscale physical models within different regions of space. This project is to develop systematic mathematical and computational methods for the compact and accurate macroscale modelling and computation of such systems for application in industrial research and development. Our sparse simulations, justified with mathematical analysis, use small bursts of particle/agent simulations, PDEs, or difference equations, to efficiently evaluate macroscale system-level behaviour. The objective is to accurately interface between disparate microscale models and establish provable predictions on how the microscale parameter spaces resolve at the macroscale.
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