Investigations into the antibacterial mechanism of action of cannabidiol. This project aims to understand how the compound cannabidiol is able to kill bacteria by examining its interactions with bacteria from a genetic and molecular level. This research is critical, because future development of cannabidiol and design of improved analogs is predicated on knowing how it works. Expected outcomes include the first detailed understanding of how cannabidiol interacts with bacteria. This should lead ....Investigations into the antibacterial mechanism of action of cannabidiol. This project aims to understand how the compound cannabidiol is able to kill bacteria by examining its interactions with bacteria from a genetic and molecular level. This research is critical, because future development of cannabidiol and design of improved analogs is predicated on knowing how it works. Expected outcomes include the first detailed understanding of how cannabidiol interacts with bacteria. This should lead to significant benefits, including high impact publications, additional collaborations with industrial partner Botanix, and a new class of antibiotics to overcome antibiotic resistance.Read moreRead less
Control points in nitrogen uptake: enhancing the response of cereals to nitrogen supply and demand. Vast amounts of nitrogen fertiliser are applied to cereal crops to maintain yields. By uncovering what limits nitrogen uptake in cereals, this project will provide the scientific basis for improving nitrogen use efficiency and decreasing fertiliser use, with significant economic and environmental benefits.
Physiology and genetics of barley grain germination in the malting and brewing industries. An international research team will provide new scientific information on barley grain germination. This detailed basic knowledge will be immediately applied in breeding programs that are aimed at improving malting and brewing quality in a commercial context. At the same time, the industry's carbon footprint will be significantly reduced.
Infill Developments: Project HOME (Housing Outcomes Metrics and Evaluation). The project plans to improve housing outcomes by evaluating housing design in the rapidly growing infill multi-residential sector, which often experiences design quality problems. Set across four global cities, the project aims to use a unique combination of design and social science methods to analyse good design and how this is produced and experienced. It is expected that this will deliver greater definition of and e ....Infill Developments: Project HOME (Housing Outcomes Metrics and Evaluation). The project plans to improve housing outcomes by evaluating housing design in the rapidly growing infill multi-residential sector, which often experiences design quality problems. Set across four global cities, the project aims to use a unique combination of design and social science methods to analyse good design and how this is produced and experienced. It is expected that this will deliver greater definition of and evidence for ‘good’ design as experienced through the real lives of Australian households. Outcomes should include robust design evaluation methods and transition strategies for cities, allowing city decision-makers to improve housing design for many people in Australian cities.Read moreRead less
Modelling stock market liquidity in Australia and the Asia Pacific Region. This project will develop new methods of assessing stock market liquidity in Australia and the Asia-Pacific region. These methods will use high frequency transactions-based data provided by the industry partner, SIRCA. The data will be the basis of smart information real time algorithms for measuring market liquidity. They will incorporate generalizations and extensions of recent developments in time series econometrics, ....Modelling stock market liquidity in Australia and the Asia Pacific Region. This project will develop new methods of assessing stock market liquidity in Australia and the Asia-Pacific region. These methods will use high frequency transactions-based data provided by the industry partner, SIRCA. The data will be the basis of smart information real time algorithms for measuring market liquidity. They will incorporate generalizations and extensions of recent developments in time series econometrics, and will be calibrated and evaluated statistically. The novel methods will be crucial to market participants and to regulators, who will be able to apply them to assess market depth and liquidity, and reduce trading costs substantially.Read moreRead less
An Advanced Numerical Technique for Stability Analysis of Mining Excavations in Jointed/Faulted Rock Masses under High Stresses. The aim of this project is to develop a sophisticated mathematical model and computational technique for the stability analysis of mining excavations in jointed/faulted rock masses. The development involves a novel solution method based on current work in finite element method, boundary element method and large-scale optimisation with partial differential equation cons ....An Advanced Numerical Technique for Stability Analysis of Mining Excavations in Jointed/Faulted Rock Masses under High Stresses. The aim of this project is to develop a sophisticated mathematical model and computational technique for the stability analysis of mining excavations in jointed/faulted rock masses. The development involves a novel solution method based on current work in finite element method, boundary element method and large-scale optimisation with partial differential equation constraints. The work is extremely important to the mining industry in Australia, as the outcomes of the project will provide engineers with an innovative simulation technique to optimise mine design and to predict and control rock failure so as to reduce personnel injuries and death toll in mine sites.Read moreRead less
Computational methods in atomic collision theory. We will develop computational methods for solving interactions between particles on the atomic scale. Computational problems, of particular interest to the industry partner, are the treatment of large-scale ill-conditioned linear systems, and the extension of the Gaussian molecular structure package to collision physics. We have been world-leaders in the field of atomic collision theory for almost a decade, and now, utilising the latest software ....Computational methods in atomic collision theory. We will develop computational methods for solving interactions between particles on the atomic scale. Computational problems, of particular interest to the industry partner, are the treatment of large-scale ill-conditioned linear systems, and the extension of the Gaussian molecular structure package to collision physics. We have been world-leaders in the field of atomic collision theory for almost a decade, and now, utilising the latest software and hardware, will have the capacity to extend the numerical techniques to a vast range of collision systems of interest to science and industry, where visualisation and sheer computer power will play a major role in both
code development and production runs.Read moreRead less
A Robust Optimization Technique for Identifying Geomechanical Parameters Using In-situ Measurements. The aim of this project is to develop a robust optimisation technique for identifying geomechanical parameters for subsequent stability analysis of rock structures in particular open pits. The development involves a novel solution method based on current work in finite element method and large-scale optimisation with partial differential equation constraints. The outcomes of the project will prov ....A Robust Optimization Technique for Identifying Geomechanical Parameters Using In-situ Measurements. The aim of this project is to develop a robust optimisation technique for identifying geomechanical parameters for subsequent stability analysis of rock structures in particular open pits. The development involves a novel solution method based on current work in finite element method and large-scale optimisation with partial differential equation constraints. The outcomes of the project will provide a sophisticated numerical technique for geotechnical engineers/scientists to determine geomechanical parameters accurately from in-situ observation and displacement measurements, leading to the optimal design of rock structures in subsequent analysis.Read moreRead less
Collision Avoidance in Shipping Lanes via Intelligent Sensor Data Fusion . This project aims to develop an online maritime traffic monitoring system for reliable collision/contact avoidance that exploits complementary data from high-resolution airborne sensors and surface vessel sensors. Our approach is based on optimal scheduling and fusion of the sensor data and possibly other sources of data to construct a comprehensive dynamic picture of maritime traffic, in real-time. Moreover, the proposed ....Collision Avoidance in Shipping Lanes via Intelligent Sensor Data Fusion . This project aims to develop an online maritime traffic monitoring system for reliable collision/contact avoidance that exploits complementary data from high-resolution airborne sensors and surface vessel sensors. Our approach is based on optimal scheduling and fusion of the sensor data and possibly other sources of data to construct a comprehensive dynamic picture of maritime traffic, in real-time. Moreover, the proposed methodology enables quantification of confidence in the predictions. This will provide ship owners, directly to their vessels and/or at the fleet management centres, information such as weather reports, reliable collision/no-collision warnings and avoidance strategies, on-the-fly. Read moreRead less
Fertility crisis: harnessing the genomic tension behind pollen fertility in sorghum. Hybrid sorghum varieties yield more grain than inbred varieties but the production seed for farmers can be difficult. This project will identify the genes responsible for a trait that makes hybrid seed production possible and this knowledge will help raise sorghum yields in Australian and in some of the world’s poorest countries.