Advanced matrix-analytic methods with applications. Over the last twenty-five years, matrix-analytic methods have proved to be very successful in formulating and analysing certain classes of stochastic models. Motivated by applications, this project will investigate more advanced matrix-analytic methods than have hitherto been studied.
Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
Change Detection in Causal Relationships and Measurement of Systemic Risk. Empirical measures of interconnectedness between financial institutions based on tests of Granger causality are currently used in detecting systemic risk. However, researchers need to define periods of calm and stress exogenously in order to implement these tests appropriately. This project aims to develop a new procedure to identify changes in causal relationships and the timing of these changes. The new approach has the ....Change Detection in Causal Relationships and Measurement of Systemic Risk. Empirical measures of interconnectedness between financial institutions based on tests of Granger causality are currently used in detecting systemic risk. However, researchers need to define periods of calm and stress exogenously in order to implement these tests appropriately. This project aims to develop a new procedure to identify changes in causal relationships and the timing of these changes. The new approach has the potential to be a significant improvement in the real-time identification of emerging turmoil in financial markets and provide an improved method for the detection of systemic risk. The new test procedure will be implemented using data for financial and non-financial institutions across Europe, the US and Australia.Read moreRead less
Tectonic geography of the world's oldest petroleum play, the McArthur Basin. This projects aims to develop a 4D tectonic geography framework to support the effective exploration of the McArthur Basin. This project will construct this by a) investigating the evolving tectonic setting, b) examining intra-basin correlations and trace the source to sink sediment provenance, c) unraveling the depositional geography using novel isotopic proxies, and, d) constructing the subsequent thermal history of ....Tectonic geography of the world's oldest petroleum play, the McArthur Basin. This projects aims to develop a 4D tectonic geography framework to support the effective exploration of the McArthur Basin. This project will construct this by a) investigating the evolving tectonic setting, b) examining intra-basin correlations and trace the source to sink sediment provenance, c) unraveling the depositional geography using novel isotopic proxies, and, d) constructing the subsequent thermal history of the basin. The techniques developed through this project will de-risk the exploration for petroleum in this basin, and be applicable in opening up Proterozoic petroleum elsewhere in Australia and internationally.Read moreRead less
Hybrid Remote Area Power Systems with Hydrogen Energy Storage for Isolated and Regional Communities. The distances and difficulties of transporting diesel to remote areas substantially add to the cost of electricity - making it many times the cost of supplies available from the grid. Consistency of electricity supply is dependent on reliable transport access and substantial storage for fuel on site. This project will reduce emissions in energy generation and provide the opportunity for mainly ....Hybrid Remote Area Power Systems with Hydrogen Energy Storage for Isolated and Regional Communities. The distances and difficulties of transporting diesel to remote areas substantially add to the cost of electricity - making it many times the cost of supplies available from the grid. Consistency of electricity supply is dependent on reliable transport access and substantial storage for fuel on site. This project will reduce emissions in energy generation and provide the opportunity for mainly renewable, high-quality electricity supplies at reduced cost for remote and isolated communities. This will make communities more self-sufficient, enhance the quality of life and provide opportunities for initiatives, including economic and employment generating activities, to benefit the communities.Read moreRead less
Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategi ....Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategies for effective operation and control of hydro turbines with Basslink. Particular attention will be paid to the quality and reliability of electricity supply in Tasmania.Read moreRead less
On-line Monitoring and Modelling of Electric Loads for Improving Operational Conditions of Power Systems. Recently, the Tasmanian Electricity System has been connected to the National Electricity Market through Basslink. The behaviour of loads to deviations in frequency and voltage becomes critical when transmission constraints begin to control market outcomes. The project will deliver vital information regarding load behaviour and models representing load responses to frequency and voltage excu ....On-line Monitoring and Modelling of Electric Loads for Improving Operational Conditions of Power Systems. Recently, the Tasmanian Electricity System has been connected to the National Electricity Market through Basslink. The behaviour of loads to deviations in frequency and voltage becomes critical when transmission constraints begin to control market outcomes. The project will deliver vital information regarding load behaviour and models representing load responses to frequency and voltage excursions with the objective of optimising power exchanges within the National Electricity Market. This will allow Tasmania to take advantage of various renewable technologies. The research will focus on the quality of electricity supply in Tasmania and the national power grid, and on the consequent economic benefits.Read moreRead less
Integration of Distributed and Renewable Power Generation into Electricity Grid Systems. This project aims to contribute into infrastructure development for connection of distributed and renewable power generation with electrical grid systems. The project proposes to develop innovative methodologies for cost-effective operation and control, protection coordination and fault detection, islanding operation, grid interaction and voltage instability with distributed and renewable generation. This pr ....Integration of Distributed and Renewable Power Generation into Electricity Grid Systems. This project aims to contribute into infrastructure development for connection of distributed and renewable power generation with electrical grid systems. The project proposes to develop innovative methodologies for cost-effective operation and control, protection coordination and fault detection, islanding operation, grid interaction and voltage instability with distributed and renewable generation. This project has special application for facilitating integration of regional renewable and distributed energy sources, such as wind, solar, mini-hydro, etc. into national grid systems.Read moreRead less
Viscous Effects in Free-Surface Flows. Australia has a proud record of achievement in the field of free-surface fluid mechanics. This project will build and extend these research achievements. It will provide new information about how fluid layers overturn and mix, which is an important process in oceanography. It will examine the sloshing behaviour of fluid in moving storage tanks, which is important in fuel transport and building design. The project will develop new mathematical methods fo ....Viscous Effects in Free-Surface Flows. Australia has a proud record of achievement in the field of free-surface fluid mechanics. This project will build and extend these research achievements. It will provide new information about how fluid layers overturn and mix, which is an important process in oceanography. It will examine the sloshing behaviour of fluid in moving storage tanks, which is important in fuel transport and building design. The project will develop new mathematical methods for solving these problems accurately, and will contribute to the next generation of research mathematicians in Australia. Read moreRead less
Detecting financial contagion using high frequency data. Financial crises spread extraordinarily quickly. However, existing tools for measuring this spread use relatively low frequency data. This project develops tools for measuring and detecting periods of stress and the effects of financial contagion in financial markets, using high frequency data based on recorded transaction prices.