Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a ....Improving the efficiency of CRISPR gene editing in cells. Human red blood cells are well-characterised and the globin gene locus is a model system for the study of gene regulation. Gene editing technologies and delivery tools are evolving rapidly and the globin gene locus is the perfect model for gene editing optimisation. This collaboration between UNSW Sydney and CSL aims to bring together our combined expertise and new technologies to develop an optimal platform for genetic modification in a red blood cell line. Simultaneously, this project aims to generate fundamental insights into mechanisms of human gene regulation. The technological and biological outcomes of this project will be of benefit for future gene editing applications.Read moreRead less
The culture of implementing Freedom of Information in Australia. In partnership with three Australian Information Commissioners/Ombudsmen this project aims to map the culture of administering Freedom of Information (FOI) laws across a number of Australian jurisdictions. The study aspires to capture and analyse the attitudes among FOI practitioners, government agency managements and political leaders toward information access implementation. The project aims to provide the partner organisations w ....The culture of implementing Freedom of Information in Australia. In partnership with three Australian Information Commissioners/Ombudsmen this project aims to map the culture of administering Freedom of Information (FOI) laws across a number of Australian jurisdictions. The study aspires to capture and analyse the attitudes among FOI practitioners, government agency managements and political leaders toward information access implementation. The project aims to provide the partner organisations with an increased understanding of the culture of administering FOI to inform training/awareness programs and campaigns in order to increase the functionality of FOI. Well-functioning access to information systems is crucial both for good governance and Australia's participation in the digital economy.
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Insecure Work and the Mental Health of Workers and their Families. This project aims to explore the relationship between insecure work and mental health by applying advanced econometric methods to large survey and administrative datasets, and newly collected survey data. This project expects to provide causal policy-relevant estimates of how insecure work is affecting the wellbeing of workers and their families, and for whom the effects are most harmful. It also expects to inform on how poor men ....Insecure Work and the Mental Health of Workers and their Families. This project aims to explore the relationship between insecure work and mental health by applying advanced econometric methods to large survey and administrative datasets, and newly collected survey data. This project expects to provide causal policy-relevant estimates of how insecure work is affecting the wellbeing of workers and their families, and for whom the effects are most harmful. It also expects to inform on how poor mental health influences the types of jobs that people enter into. This should provide significant benefits, including evidence needed to improve existing workplace and employment programs, and evidence ensuring that assistance is efficiently targeted to those workers and industries with the greatest need.Read moreRead less
A Scenario Planning Tool - Improving the Bikeability of Our Cities. This project aims to produce a data framework and interactive planning support tool, in collaboration with Australian government agencies, to explore various bicycle infrastructure scenarios and assess their potential impacts. This will be a game changer for the transport sector, as the lack of data-driven approaches focused on active mobility has restricted the development of evidence-based business cases for cycling infrastruc ....A Scenario Planning Tool - Improving the Bikeability of Our Cities. This project aims to produce a data framework and interactive planning support tool, in collaboration with Australian government agencies, to explore various bicycle infrastructure scenarios and assess their potential impacts. This will be a game changer for the transport sector, as the lack of data-driven approaches focused on active mobility has restricted the development of evidence-based business cases for cycling infrastructure investment, when compared to motorised transport. Benefits from this project to the nation include more informed and optimised investment in cycling, increase in cycling modal share, reduction of emissions and congestion, and improvement of safety and health outcomes from cycling.Read moreRead less
The new digital governance of welfare to work. This project aims to analyse the implementation of a 'digital first' employment services system, its effects on frontline services and governance, and its potential for policy learning. It expects to generate new knowledge on how digitalisation changes interactions between jobseekers, providers, employers and the government, by working with our industry partners in a collaborative innovation lab. Expected outcomes of this project include a theoretic ....The new digital governance of welfare to work. This project aims to analyse the implementation of a 'digital first' employment services system, its effects on frontline services and governance, and its potential for policy learning. It expects to generate new knowledge on how digitalisation changes interactions between jobseekers, providers, employers and the government, by working with our industry partners in a collaborative innovation lab. Expected outcomes of this project include a theoretically informed, and practically tested, model of how digitalisation can promote service design and policy innovation that benefits jobseekers and employers. This should provide significant benefits for welfare system design, service outcomes, and policy learning nationally and internationally. Read moreRead less
Housing energy efficiency transitions. This project aims to provide an analysis of housing retrofit and its links with household energy costs. It includes householders across eight global urban sites, as well as the businesses that supply retrofit services. The project will analyse the retrofit experience of both energy poor and other households, providing an internationally significant evidence base. Outcomes include a robust empirical evidence base on the implications of retrofit for househol ....Housing energy efficiency transitions. This project aims to provide an analysis of housing retrofit and its links with household energy costs. It includes householders across eight global urban sites, as well as the businesses that supply retrofit services. The project will analyse the retrofit experience of both energy poor and other households, providing an internationally significant evidence base. Outcomes include a robust empirical evidence base on the implications of retrofit for households to tailor actions that will shape the lives of residents in Australian households.Read moreRead less
Evolution of Proterozoic multistage rift basins – key to mineral systems. This project will deliver a new quantitative and integrated exploratory framework for the mineral industry in Australia’s frontier sedimentary basins by integrating the latest advances in laboratory experimental tectonics with thermo-mechanical numerical, surface process and geophysical modelling. The project will use northern Australian basins as a natural laboratory to address the fundamental processes involved in the de ....Evolution of Proterozoic multistage rift basins – key to mineral systems. This project will deliver a new quantitative and integrated exploratory framework for the mineral industry in Australia’s frontier sedimentary basins by integrating the latest advances in laboratory experimental tectonics with thermo-mechanical numerical, surface process and geophysical modelling. The project will use northern Australian basins as a natural laboratory to address the fundamental processes involved in the development of sedimentary ore systems. The project will investigate how they can be detected by modern exploration techniques using a multidisciplinary approach with a team of experts with backgrounds in mineral and petroleum systems. Read moreRead less
Dynamic Deep Learning for Electricity Demand Forecasting. This project aims at developing a deep learning technology for high resolution electricity demand forecasting and residential demand response modelling. Electricity consumption data are dynamic and highly uncertain. The deep learning technology expects to provide accurate demand forecasting, and thus enabling optimal use of existing
grid assets and guiding future investments. The expected outcome can support data-driven decision-making in ....Dynamic Deep Learning for Electricity Demand Forecasting. This project aims at developing a deep learning technology for high resolution electricity demand forecasting and residential demand response modelling. Electricity consumption data are dynamic and highly uncertain. The deep learning technology expects to provide accurate demand forecasting, and thus enabling optimal use of existing
grid assets and guiding future investments. The expected outcome can support data-driven decision-making in Australia's electricity distribution network planning and operation by considering future challenges such as integrating battery storage and electric vehicles into the grid, and thus providing reliable energy. The project expects to train next generation expert workforce for Australia's future power grid.Read moreRead less
Intergenerational Disadvantage: Causes, Pathways, and Consequences. This Project aims to prevent poor Australian children from becoming poor adults by developing scientific evidence and creative policy approaches to overcome entrenched disadvantage. The Project will generate new knowledge on how social assistance dependence is linked across generations using new Australian data. Expected outcomes are the identification of i) the causal link between parents’ and children’s social assistance depen ....Intergenerational Disadvantage: Causes, Pathways, and Consequences. This Project aims to prevent poor Australian children from becoming poor adults by developing scientific evidence and creative policy approaches to overcome entrenched disadvantage. The Project will generate new knowledge on how social assistance dependence is linked across generations using new Australian data. Expected outcomes are the identification of i) the causal link between parents’ and children’s social assistance dependence; ii) the pathways through which youths overcome disadvantage; and iii) the role of family structure in transmitting disadvantage. Transforming the evidence base, the findings will have significant benefits in redesigning the Australian social safety net, promoting social and economic mobility.Read moreRead less
Multi-phase modelling and characterisation of mudrush hazard in cave mining. A mudrush is a sudden, uncontrolled flow of wet fine particles (mud) into an underground mine that damages equipment, infrastructure, and can even cause fatalities. This project aims to develop cost-effective management and monitoring of mudrush hazards within the at-risk Carrapateena cave mine operated by OZ Minerals. Building on recent technological and numerical advances, a novel experimental–theoretical–numerical ap ....Multi-phase modelling and characterisation of mudrush hazard in cave mining. A mudrush is a sudden, uncontrolled flow of wet fine particles (mud) into an underground mine that damages equipment, infrastructure, and can even cause fatalities. This project aims to develop cost-effective management and monitoring of mudrush hazards within the at-risk Carrapateena cave mine operated by OZ Minerals. Building on recent technological and numerical advances, a novel experimental–theoretical–numerical approach will be used to simulate mudrush risk based on moisture content, particle sizes, compaction, geological conditions, and seismic energy. Outputs will include a practical framework to boost the safety, productivity, and profitability of caving operations to benefit miners and the broader resources industry.Read moreRead less