Charge-Controlled Materials for Separations of Important Resources. This project aims to develop new porous materials that are capable of greater molecular discrimination than current technologies. This project expects to advance understanding of fundamental structure-activity relationships in these materials, and synthetic targets will be geared towards materials for industrially or environmentally important chemical separations associated with metal extraction. Expected outcomes of this projec ....Charge-Controlled Materials for Separations of Important Resources. This project aims to develop new porous materials that are capable of greater molecular discrimination than current technologies. This project expects to advance understanding of fundamental structure-activity relationships in these materials, and synthetic targets will be geared towards materials for industrially or environmentally important chemical separations associated with metal extraction. Expected outcomes of this project include new insights on the underlying chemistry for tailoring crystalline microporous materials towards select applications. This should provide significant benefits, such as future low-energy and efficient technologies for industrially important separation processes with reduced financial and environmental costs.Read moreRead less
Gas Phase Studies to Catalyze a Better Understanding of Metal Reactivity. The proposed research will increase knowledge of fundamental questions related to the mechanisms of catalysis and metal ion reactivity. The insights gained will be an important addition to the knowledge base of our culture, both nationally and in the wider international context. We note that research into the behaviour and design of catalysts is a burgeoning field which reflects the great importance of this area in the int ....Gas Phase Studies to Catalyze a Better Understanding of Metal Reactivity. The proposed research will increase knowledge of fundamental questions related to the mechanisms of catalysis and metal ion reactivity. The insights gained will be an important addition to the knowledge base of our culture, both nationally and in the wider international context. We note that research into the behaviour and design of catalysts is a burgeoning field which reflects the great importance of this area in the international scientific community. Our proposal will add to fundamental knowledge and may also result in practical applications. More importantly, we will train and equip talented young people with a spectrum of skills which will make them well placed to meet the demand for highly skilled professional scientists.Read moreRead less
Synthesis of Novel Dual Acting, Selenium Containing Antioxidants. Ischemic heart disease and chronic inflammation afflict a large segment of the Australian population, especially the ageing. These states are associated with free-radicals and other reactive oxygen species and can be controlled to some extent by the application of adenosine therapy. This project will combine the activity of adenosine agonists and enhancers with selenium-containing antioxidants, used to quench reactive oxygen spe ....Synthesis of Novel Dual Acting, Selenium Containing Antioxidants. Ischemic heart disease and chronic inflammation afflict a large segment of the Australian population, especially the ageing. These states are associated with free-radicals and other reactive oxygen species and can be controlled to some extent by the application of adenosine therapy. This project will combine the activity of adenosine agonists and enhancers with selenium-containing antioxidants, used to quench reactive oxygen species, to provide a powerful new class of pharmaceutical products designed to enhance the quality of life of Australians afflicted by diseases propagated by free-radicals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100186
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Base stabilised dicarbon as a new building block for supramolecular organometallic chemistry. Diamond, coal and graphite are the forms of carbon ("allotropes") found in everyday life. The discovery of two further allotropes of carbon, the fullerenes and graphene both led to Nobel Prize awards. We have identified a method to stabilize another form of carbon, dicarbon, and will harness its properties for the formation of new materials.
New reactivity from unusual main group compounds. This project will develop new, fundamentally important, yet unusual main group compounds and investigate their reactivity. The project will lead to important fundamental advance in main group chemistry and will form the basis for cheaper and cleaner future synthetic methodologies and technologies.
Novel hydride complexes for chemical applications. Many main group elements are abundant, cheap, generally less harmful and sometimes even biocompatible compared with most other elements from the periodic table. This project will develop a range of fundamentally important well-defined molecular s-block metal and non-metal hydride complexes and investigate their chemistry and properties. These underdeveloped but emerging compound classes are of significant importance for chemical synthesis, hydro ....Novel hydride complexes for chemical applications. Many main group elements are abundant, cheap, generally less harmful and sometimes even biocompatible compared with most other elements from the periodic table. This project will develop a range of fundamentally important well-defined molecular s-block metal and non-metal hydride complexes and investigate their chemistry and properties. These underdeveloped but emerging compound classes are of significant importance for chemical synthesis, hydrogen storage and catalysis. The results emerging from this project will contribute towards the development of greener and more sustainable technologies.Read moreRead less
Advancing the Metal-Organic Chemistry of the Heavy Alkaline Earth Elements. The project will open up a new area in Australian metal based chemical research, deriving high value added products from the already existing exploitation of Australia's substantial alkaline earth metal mineral resources. Internationally recognised expertise in the design and manipulation of highly reactive chemical tools will contribute breakthrough science and innovation to the growing pharmaceutical, fine chemicals an ....Advancing the Metal-Organic Chemistry of the Heavy Alkaline Earth Elements. The project will open up a new area in Australian metal based chemical research, deriving high value added products from the already existing exploitation of Australia's substantial alkaline earth metal mineral resources. Internationally recognised expertise in the design and manipulation of highly reactive chemical tools will contribute breakthrough science and innovation to the growing pharmaceutical, fine chemicals and smart materials industry, with the potential to provide nascent and established Australian companies a competitive edge in new product development. Students will be trained in the necessary skills to succeed in and expand such technically demanding area of metal based chemistry.Read moreRead less
Polyanionic carbon ligands in metal complexes as new reagents in organometallic and inorganic chemistry. The proposed research will benefit Australia by creating a knowledge base in an internationally important area of chemistry. It addresses fundamental questions in organometallic chemistry that will be of great significance for chemical synthesis as well as for a greater understanding of structure and bonding. Through an integrated and interdisciplinary approach, the exploitation of technologi ....Polyanionic carbon ligands in metal complexes as new reagents in organometallic and inorganic chemistry. The proposed research will benefit Australia by creating a knowledge base in an internationally important area of chemistry. It addresses fundamental questions in organometallic chemistry that will be of great significance for chemical synthesis as well as for a greater understanding of structure and bonding. Through an integrated and interdisciplinary approach, the exploitation of technologies arising from this research programme will be explored. In addition to the academic community, these technologies will benefit hi-tech industries including pharmaceutical and fine chemical concerns which will gain from the use of polymetalated carbon species in organic and inorganic synthesis, catalysis and the development of new materials.Read moreRead less
Group 13 Mixed Halide-Hydride and Rare Earth Complexes - New Selective Chiral Hydridic or Low Valent Reducing Agents. This project will make a landmark contribution to two areas of metallohydride chemistry. Both studies will utilise and develop metals that have traditionally been mined and exported from these shores while concurrently imported as value added products at vastly inflated cost. This research will identify knock-on applications in order to stem this financial bias. The new paths to ....Group 13 Mixed Halide-Hydride and Rare Earth Complexes - New Selective Chiral Hydridic or Low Valent Reducing Agents. This project will make a landmark contribution to two areas of metallohydride chemistry. Both studies will utilise and develop metals that have traditionally been mined and exported from these shores while concurrently imported as value added products at vastly inflated cost. This research will identify knock-on applications in order to stem this financial bias. The new paths to rare earth (= Ln) hydrides will have broad industrial appeal, particularly for new materials, where, like similar group 13 materials, they may be used in the deposition of Ln films or even as precursors to superconducting solids. It is anticipated industrial collaboration will ensue. Australia will be promoted as a developer and innovator of frontier technologies.Read moreRead less
Metal-promoted bond functionalisation: new routes to amides and thioamides. This project aims to discover new metal-promoted methods to synthesise amides and thioamides, important structural motifs in chemistry and biology. The project will use a mechanism-based approach that integrates theory with gas- and solution-phase experiments to discover new chemical reactions. A benefit of this research will be new eco-friendly alternatives to existing processes, thereby reducing waste and eliminating t ....Metal-promoted bond functionalisation: new routes to amides and thioamides. This project aims to discover new metal-promoted methods to synthesise amides and thioamides, important structural motifs in chemistry and biology. The project will use a mechanism-based approach that integrates theory with gas- and solution-phase experiments to discover new chemical reactions. A benefit of this research will be new eco-friendly alternatives to existing processes, thereby reducing waste and eliminating toxic and expensive reagents.Read moreRead less