Switching the light on cartilage repair. Osteoarthritis is a leading cause of pain and disability in adults and affects 15 per cent of the Australian population. This project will develop a revolutionary new approach to treat joint disorders using smart materials and stem cells. The novel materials and techniques developed will help Australia maintain its leading edge in biotechnology.
Development of new systems for the commercial collection, processing and storage of adipose stem cells. This project is aimed at developing a standardised method to commercially extract and expand stem cells from adipose tissue. This product will then be available commercially as a therapeutic treatment.
Dissecting the physiology of multipotent mesenchymal stromal cells to develop vaccine candidates for respiratory disease. The project aims to gain an understanding of how a type of adult stem cell inhibits immune responses that cause asthma. The project will produce new stem cell products and facilitate the design of a vaccine for asthma and other respiratory diseases, which would greatly reduce the burden of such conditions.
Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tib ....Bone tissue engineering using innovative tubular dual-layered nanofiber meshes. Lifetime risks for long-bone fractures in Caucasians over the age of 50 are 17 per cent for women and 6 per cent for men. A clear therapeutic need exists to address the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. To address this challenge, the project’s multidisciplinary, international team will develop technologies to heal tibial defects. Furthermore, it will establish Australia's prominence in the tissue engineering field, training the next generation of young scientists and engineers. This technology will be of interest to numerous research groups and companies worldwide and will foster international collaboration, placing Australia at the forefront of this emerging field.Read moreRead less
Kesterite solar cell coated architectural stainless steel. This project aims to develop cost-effective, high-performance kesterite architectural stainless steel coated with solar cells for application in roofing, skin and facades of smart buildings. The project will integrate expertise in producing kesterite solar cells with expertise in manufacturing new steel to eliminate toxic, scarce materials and high-cost processes employed in conventional solar-driven steel. The initial target of the proj ....Kesterite solar cell coated architectural stainless steel. This project aims to develop cost-effective, high-performance kesterite architectural stainless steel coated with solar cells for application in roofing, skin and facades of smart buildings. The project will integrate expertise in producing kesterite solar cells with expertise in manufacturing new steel to eliminate toxic, scarce materials and high-cost processes employed in conventional solar-driven steel. The initial target of the project would be to increase kesterite cell efficiency to beyond 10 per cent, and ultimately beyond 17 per cent, but still at a low cost.Read moreRead less
High-performance and Cost-effective Fibre Optic Distributed Sensing System. This project aims to provide enabling technologies to manufacture high-performance and cost-effective fibre optic distributed sensing systems. Coherent optical time domain reflectometry based on Rayleigh scattering in optical fibre has been explored for distributed vibration, strain and temperature sensing. However, its susceptibility to laser phase noise, amplitude and polarisation fading hinders its widespread applicat ....High-performance and Cost-effective Fibre Optic Distributed Sensing System. This project aims to provide enabling technologies to manufacture high-performance and cost-effective fibre optic distributed sensing systems. Coherent optical time domain reflectometry based on Rayleigh scattering in optical fibre has been explored for distributed vibration, strain and temperature sensing. However, its susceptibility to laser phase noise, amplitude and polarisation fading hinders its widespread application. This project aims to apply the technologies developed in coherent optical communication to fibre optic distributed sensing. The research is planned to include design, simulation, and experimental verification of the proposed sensing system.Read moreRead less
Optimising experimental design for robust product development: a case study for high-efficiency energy generation. This project tackles key mathematical challenges to provide a powerful new methodology and tool for optimal product design, making smarter use of limited information, minimising costly trials, shortening the product cycle, and boosting the competitiveness of both the Australian manufacturing and alternative energy production industries.
Micro-roll forming of metal bipolar plates for fuel cells. This project aims to develop a novel forming technology for the production of metal bipolar plates for fuel cells: micro-roll forming. This poses a number of challenges particularly due to the low material thickness to be formed. These challenges include the development of advanced models that account for size effects in the process and represent the unique deformation conditions and material fracture behaviour. The project plans to prod ....Micro-roll forming of metal bipolar plates for fuel cells. This project aims to develop a novel forming technology for the production of metal bipolar plates for fuel cells: micro-roll forming. This poses a number of challenges particularly due to the low material thickness to be formed. These challenges include the development of advanced models that account for size effects in the process and represent the unique deformation conditions and material fracture behaviour. The project plans to produce prototypes and to compare part complexity with that achievable by conventional micro stamping. The intended outcome of the project includes advanced computer models for process design and the new micro-forming technology validated through extensive laboratory and plant trials.Read moreRead less
An investigation of the impacts of increased power supply to the national grid by wind generators on the Australian electricity industry. The aim of this project is to discover the most economical and effective way to accommodate large increases in wind power into the national grid and to understand the effects on the national electricity market. This is crucial to ensure stability of electricity supply and affordable prices in the transition towards a low carbon economy.
On-chip spectroscopy and hyperspectral imaging for remote environments. On-chip spectroscopy and hyperspectral imaging for remote environments. This project aims to investigate techniques and materials for building optical spectrometers based on micromachines, usable in portable ground-based and drone-mounted applications in remote environments. Optical spectroscopy is now an accepted technique for materials detection and analysis. The advent of low-cost drone aircraft makes the potential applic ....On-chip spectroscopy and hyperspectral imaging for remote environments. On-chip spectroscopy and hyperspectral imaging for remote environments. This project aims to investigate techniques and materials for building optical spectrometers based on micromachines, usable in portable ground-based and drone-mounted applications in remote environments. Optical spectroscopy is now an accepted technique for materials detection and analysis. The advent of low-cost drone aircraft makes the potential applications of spectroscopy in an imaging form immense. The project expects the resulting low-cost and highly portable technology will transform Australian industry, including securing Australia’s food supply by improving farming practices, aiding mineral exploration, and enhancing capabilities for monitoring Australia’s coastline.Read moreRead less