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Risk factors for the development of paediatric anxiety disorders. Anxiety disorders are common and debilitating forms of disability affecting Australian children. This project blends strategic basic research with clinical application to advance our understanding of the causes of these disorders. By examining underlying child- and parent-based mechanisms by which children at greatest risk for these disorders transition to anxiety-disordered status, this project will lead to improved prevention an ....Risk factors for the development of paediatric anxiety disorders. Anxiety disorders are common and debilitating forms of disability affecting Australian children. This project blends strategic basic research with clinical application to advance our understanding of the causes of these disorders. By examining underlying child- and parent-based mechanisms by which children at greatest risk for these disorders transition to anxiety-disordered status, this project will lead to improved prevention and treatment strategies, which will improve the lives of affected children and their families and significantly reduce the financial burden on the Australian health care system.Read moreRead less
Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be rea ....Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be reactivated in these diseases for recovery of function. This project seeks to understand normal development of the brain and in doing so it will expose novel targets for therapy in the aged. Read moreRead less
Sino-Australian neurogenetics initiative. This project will undertake large population studies to identify genes that are associated with motor neuron disease, schizophrenia and intracranial haemorrhage. The project will determine genetic markers, aid development of diagnostic tools and identify new therapeutic targets for these common heritable neurological diseases.
Preventing Suicide: A psychological autopsy study of the last contact with a health professional before suicide. In Australia, 48% of all suicides in 2000 were by 35-64 year olds; an additional 13% were by 65 years and over. This study will examine the last clinical contact older suicide victims had with health professionals in order to determine whether this contact offers an opportunity for intervention. For the first time in Australia, GP's, health professionals, and the deceased's next-of-ki ....Preventing Suicide: A psychological autopsy study of the last contact with a health professional before suicide. In Australia, 48% of all suicides in 2000 were by 35-64 year olds; an additional 13% were by 65 years and over. This study will examine the last clinical contact older suicide victims had with health professionals in order to determine whether this contact offers an opportunity for intervention. For the first time in Australia, GP's, health professionals, and the deceased's next-of-kin will be interviewed to determine the context surrounding the deceased's death, and the abilities of health professionals to identify warning signs and to intervene prior to suicide. Given our ageing population, the outcomes will be significant in educating all health professionals to identify suicidal signs, and to prevent premature death in the elderly.Read moreRead less
A longitudinal study into the development of personal vulnerabilities and well-being in adolescence. Character strengths such as empathy and emotion management skills are potentially teachable and help prevent an adolescent from experiencing difficulties in social, emotional, and academic adjustment. This longitudinal study examines the temperament and environmental factors that promote character strengths in adolescents.
The role of social-emotional learning in attaining literacy and numeracy. This project aims to characterise variability in developmental pathways to literacy and numeracy, and the factors that contribute to this variation, utilising innovative analytical approaches and population data. This project expects to generate new knowledge regarding the role of school-based social-emotional learning programs in supporting children’s achievement of literacy and numeracy. Expected outcomes of the project ....The role of social-emotional learning in attaining literacy and numeracy. This project aims to characterise variability in developmental pathways to literacy and numeracy, and the factors that contribute to this variation, utilising innovative analytical approaches and population data. This project expects to generate new knowledge regarding the role of school-based social-emotional learning programs in supporting children’s achievement of literacy and numeracy. Expected outcomes of the project include enhanced collaboration with government to deliver policy-relevant information on the most effective targets and timing for delivering social-emotional programs that maximise academic learning. This should assist policy makers to develop better strategies to support every child’s academic achievement.Read moreRead less
Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in thei ....Effectiveness of social skills training for children with autism. Our industry partner, Aspect Australia, is one of the world's largest providers of educational and other services for people with autism. The demonstration of effectiveness of the program in Aspect classes will likely lead to widespread use and benefit of the program in the education sector nationally and internationally. This in turn would lead to potential lessening of disability in children with autism with improvements in their mental health and significant cost savings to the community.Read moreRead less
Into the thirties: Persistence and social consequences of risky drinking. The aim of this project is to investigate the social contexts, roles and consequences of problematic alcohol use in adults aged 30, using long term longitudinal resources able to observe the development and corollary of alcohol use over time. It is posited that such drinkers entering their third decade of life persist in levels of problematic alcohol use typically associated with younger ages and that this leads to social ....Into the thirties: Persistence and social consequences of risky drinking. The aim of this project is to investigate the social contexts, roles and consequences of problematic alcohol use in adults aged 30, using long term longitudinal resources able to observe the development and corollary of alcohol use over time. It is posited that such drinkers entering their third decade of life persist in levels of problematic alcohol use typically associated with younger ages and that this leads to social consequences, such as gender specific risks, relationship conflicts and more severe long term effects. Outcomes from this project are expected to inform the generation of relevant prevention and intervention strategies aimed to address problem drinking in adult Australians.Read moreRead less
The future of childhood anxiety treatment: translating cognitive-neuroscience insights into clinical practice. The newest adult anxiety treatments use computer-based tasks that provide practice in overcoming maladaptive thinking patterns. This project is among the first to test this approach with children by developing a simple intervention that can be done at home. This new treatment will significantly reduce the burden of disease in Australia.
Mapping the learning mechanisms linking adversity with maladjustment. Exposure to adversity, such as violence, neglect and natural disasters, is common and a powerful risk factor for emotional maladjustment. Yet knowledge of the underlying mechanisms linking adversity with emotional maladjustment is remarkably limited. By drawing from theories of adversity and learning and utilising novel experimental methodology, this project aims to map how adverse experiences have different negative effects o ....Mapping the learning mechanisms linking adversity with maladjustment. Exposure to adversity, such as violence, neglect and natural disasters, is common and a powerful risk factor for emotional maladjustment. Yet knowledge of the underlying mechanisms linking adversity with emotional maladjustment is remarkably limited. By drawing from theories of adversity and learning and utilising novel experimental methodology, this project aims to map how adverse experiences have different negative effects on daily emotional wellbeing by disrupting the mechanisms underlying how people learn to acquire and reduce reactivity to new threats. Expected benefits include new knowledge about the pathways linking adversity with psychopathology as well as the vital evidence-base for clear targets for behavioural interventions. Read moreRead less