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Sirtuins And The Molecular Epidemiology Of Frailty In Older Men
Funder
National Health and Medical Research Council
Funding Amount
$483,246.00
Summary
People in Australia are living longer and longer and yet little is known about the underlying biology of the ageing process. This project will investigate the role of a number of molecular and cellular factors in the aetiology of frailty in a group of more than 1400 older men who are already participating in the Concord Health and Ageing in Men Project. A particular focus of the project are sirtiuns, a group of enzymes recently found to be associated with longer life in several animal models.
Identifying The Social, Personal And Health Needs Of Men Living With Hepatitis C.
Funder
National Health and Medical Research Council
Funding Amount
$215,906.00
Summary
This study will identify the health and social support needs of men who are infected with hepatitis C and will complement a similar study currently being conducted with women. At present, there is little information about the ways that hepatitis C impacts on the lives of men and research on the impact of related diseases (HIV-AIDS) strongly suggests that hepatitis C is likely to affect men in different ways to women, both economically, personally and physically. This is further complicated by th ....This study will identify the health and social support needs of men who are infected with hepatitis C and will complement a similar study currently being conducted with women. At present, there is little information about the ways that hepatitis C impacts on the lives of men and research on the impact of related diseases (HIV-AIDS) strongly suggests that hepatitis C is likely to affect men in different ways to women, both economically, personally and physically. This is further complicated by the fact that the majority of infected men have a history of injecting drug use, which coupled with the stigma often attached to chronic diseases such as hepatitis C, negatively impacts on men's lives. Of specific concerns are issues around employment, access to appropriate health care and social support. Six hundred men from Melbourne and regional Victoria will be surveyed. We will ask them questions about the social and personal impact of HCV on relationships with partners, the availability and accessibillity of appropriate treatment, care and support services and other ways that living with hepatitis C has affected their lives. The findings of this study will be used to help policy makers and service providers make decisions about education, support and care services so that they best suit the needs of men who have hepatitis C.Read moreRead less
Randomized Controlled Trial Of A Video-delivered Intervention For The Early Detection Of Melanoma In Men 50+ Years
Funder
National Health and Medical Research Council
Funding Amount
$511,694.00
Summary
Unfortunately, men over 50 years are most at risk to die from melanoma. Skin self-examination, where a man inspects the skin of his whole body with the help of a mirror or another person, and rapid presentation to a doctor without delay if he detects a suspicious lesion has the potential to increase awareness for the skin and to improve early diagnosis. We want to assess if we can increase the rate of skin self-examination in men 50 years and over through a video-delivered intervention.
Talking The Walk And Walking The Talk: A Descriptive Follow-up Study Of Refugee Mens Health, Wellbeing And Resettlement.
Funder
National Health and Medical Research Council
Funding Amount
$280,693.00
Summary
Although a significant proportion of refugees resettled in Australia are men, the health needs of male refugees remain largely unknown. This descriptive follow-up study aims to examine in depth, the health, well-being and resettlement experiences of 233 adult Sudanese and Iraqi refugee men living in the Melbourne metropolitan area. Participants will be followed-up four times per year for three years using both quantitative and qualitative methods of data collection. The study will produce eviden ....Although a significant proportion of refugees resettled in Australia are men, the health needs of male refugees remain largely unknown. This descriptive follow-up study aims to examine in depth, the health, well-being and resettlement experiences of 233 adult Sudanese and Iraqi refugee men living in the Melbourne metropolitan area. Participants will be followed-up four times per year for three years using both quantitative and qualitative methods of data collection. The study will produce evidence based knowledge of those aspects of health and wellbeing that are important for refugee men, and the identification of elements-resources that support refugee men during resettlement.Read moreRead less
MatesMonitor: Evaluating Suicide Prevention In The Construction Industry
Funder
National Health and Medical Research Council
Funding Amount
$628,742.00
Summary
We will evaluate a smart-phone based suicide prevention program for the construction industry called MatesMonitor. This will complement face-to-face training provided by an industry-wide suicide prevention program. MatesMonitor will provide education and awareness about suicide prevention and additional social support through regular contacts with participants. We anticipate MatesMonitor will result in improved suicide prevention literacy, and reduced suicide ideation and self harm.
Transition to adulthood: the wellbeing of young women and men in Australia. How do young Australians make the transition from adolescence to adulthood in the 21st century, and is it different for women and men? This project seeks to understand the life transitions, plans, and emotional wellbeing of young Australians, providing evidence to underlie policy that supports the wellbeing of all emerging adults.
Hypospadias, is a common defect, in which the urethra opens abnormally along the shaft of the penis not at the tip. It affects 1 in every 125 boys born in Victoria each year. However, the cause(s) of over two-thirds of these cases cannot be explained. Our studies using marsupials show that this process is mediated by a hormone (5alpha-androstanediol), with previously undetermined physiological function. This study will provide novel data on the interactions of the genes and hormones that result ....Hypospadias, is a common defect, in which the urethra opens abnormally along the shaft of the penis not at the tip. It affects 1 in every 125 boys born in Victoria each year. However, the cause(s) of over two-thirds of these cases cannot be explained. Our studies using marsupials show that this process is mediated by a hormone (5alpha-androstanediol), with previously undetermined physiological function. This study will provide novel data on the interactions of the genes and hormones that result in defects of penile development.Read moreRead less
Activin And Its Binding Protein, Follistatin Regulate Functions Of The Epididymis And Vas Deferens
Funder
National Health and Medical Research Council
Funding Amount
$612,736.00
Summary
Male reproductive disease is a serious health issue for many men and their partners. Worldwide, malformations of the male reproductive organs are increasing, infections and chronic inflammation of the genitourinary tract beset sexually active men and aging men, and infertility afflicts one in seven couples desiring children. The causes underlying these conditions are not well-understood. These studies are intended to identify new approaches for preventing and treating these conditions.
Selective Estrogen Receptor Modulators - A New Adjunctive Treatment For Men With Schizophrenia?
Funder
National Health and Medical Research Council
Funding Amount
$816,603.00
Summary
One-third of people with schizophrenia do not respond well to antipsychotic medication treatment.There is an urgent need to develop new treatments.We have conducted world-first studies showing that estrogen treatment is highly successful in treating women with schizophrenia.Our research is a trial of SERM (selective estrogen receptor modulator), a new form of “brain estrogen” in men with persistent schizophrenia. We hope to reduce the disability caused by persistent psychotic symptoms.