I am an immunologist-cell biologist investigating the regulation of human immune responses in health and disease. The overall goal of this work is to improve immunity in individuals with immunodeficiencies, or during vaccination, or to attenuate immune re
Prof Carbone’s laboratory specialises in the study of immunity at the body surfaces. These surfaces include skin and mucosal tissues such as respiratory and gastrointestinal tract, all of which are the common points of entry for a variety of infectious agents. He has found that there exist cells at these peripheral sites that are separate from the immune components that one finds in the blood and, more importantly, that provide a profound level of protection during new infection. He now propose ....Prof Carbone’s laboratory specialises in the study of immunity at the body surfaces. These surfaces include skin and mucosal tissues such as respiratory and gastrointestinal tract, all of which are the common points of entry for a variety of infectious agents. He has found that there exist cells at these peripheral sites that are separate from the immune components that one finds in the blood and, more importantly, that provide a profound level of protection during new infection. He now propose to determine how best to induce this type of peripheral immune protection and how one can exploit these mechanisms for the purpose of infection control.Read moreRead less
I am a cellular immunologist with expertise in antigen processing-presentation, CTL determinant selection and immunodominance, T cell differentiation and, cancer immunotherapeutic trials and cancer vaccine development.
I am a molecular geneticist with a main research focus in the identification and characterisation of genes and molecular pathways involved in intellectual disability and epilepsy.
My research centers on the formation and function of T cells, with particular emphasis on normal T cell homeostasis and how T cells respond to foreign antigens while tolerating self antigens.
I study basic mechanisms of the interaction of pathogens and particles with the immune system, to gain insight into mechanisms of adjuvanticity, immune evasion and generally immuno-modulation. With this specific insight I further pursue the development of