Centre Of Research Excellence For The Study Of Naevi
Funder
National Health and Medical Research Council
Funding Amount
$2,496,835.00
Summary
Most melanomas grow adjacent to or within pre-existing benign neoplasms of the skin called naevi. Many studies have shown that the number of nevi on an individual predicts their risk of developing melanoma. New naevi form and existing ones change regularly in children and also adults. While previous work aimed to reduce the burden of melanoma has focussed on malignant tumours, much can be learned from increasing our understanding of tumorigenesis by studying benign tumours such as naevi.
Skin cancers, including melanoma, present a significant health, social and economic burden in Australia. Despite the rising incidence of melanoma, the most deadly form of skin cancer, there is currently no national or population-based screening program available. The aim of this CRE is to identify how novel skin imaging technologies can be integrated into the pathway to improve early detection, and ultimately reduce the health and economic burden caused by melanoma skin cancer.
Centre Of Research Excellence In Melanoma: Person, Tumour And System-focussed Knowledge To Drive Better Outcomes In Melanoma
Funder
National Health and Medical Research Council
Funding Amount
$2,486,945.00
Summary
This Centre for Research Excellence in Melanoma will address three pivotal questions: how best to identify and conduct surveillance of the person with a high risk of melanoma, how best to manage the person who has developed a melanoma with high potential for relapse, and how best to improve support, survivorship and the patient experience. Economic evaluation, policy and implementation research are integral to the research plan.
The Centre for Research Excellence in Sun and Health (CRESH) aims to build an evidence base that will lead to the development of regionally appropriate public health guidelines that will balance the adverse and beneficial effects of sun exposure to optimise the health of the Australian community.
Centre Of Research Excellence - REduce The Burden Of Antimicrobial ReSistance Through OPtimal, PersONalised Dosing (RESPOND)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Each year more than 17 million people die from infectious diseases. Many of these deaths are due to the poor use of antimicrobial drugs and an increase in infections caused by antimicrobial-resistant 'superbugs'. CRE RESPOND will enable an optimal treatment of infection by empowering clinicians with an evidence-based, patient-centred approach to guide antimicrobial dosing. We will generate new knowledge, educate healthcare workers, and build research capacity through our network of collaborators
A National Centre For Antimicrobial Stewardship: Using A One Health Approach
Funder
National Health and Medical Research Council
Funding Amount
$2,601,801.00
Summary
The emergence of antimicrobial resistance is a serious worldwide problem. The National Centre for Antimicrobial Stewardship will use a One Health approach to address antibiotic use in both humans and animals. We will focus on hospitals, aged care, and general practice. In animal health, we will investigate links between antibiotic use in animal production and resistant bacteria, and evaluate usage in companion animals. The aim is to promote appropriate antibiotic use in animal and human health.
Centre For REdefining Antibiotic Use To ReDUce ResistanCE And Prolong The Lives Of Antibiotics (REDUCE)
Funder
National Health and Medical Research Council
Funding Amount
$2,158,296.00
Summary
Ineffective dosing of antimicrobials has contributed to the escalation of antimicrobial resistance which now pervades the healthcare system. Patients in the intensive care unit and post-transplant are examples of patients who commonly have infections, are more likely to fail treatment and have resistant microbes emerge. In these studies we will characterise the doses of antimicrobials that should be used in these difficult-to-treat patients and rapidly share these for routine clinical use.
Centre For Research Excellence In Malaria Elimination
Funder
National Health and Medical Research Council
Funding Amount
$2,470,291.00
Summary
The CRE will work to accelerate progress towards malaria elimination in our region, through Surveillance, to develop better ways to monitor malaria transmission and discover who is infected, and to track movement of malaria parasites and spread of drug resistance. Diagnosis, to develop and test new, more sensitive ways of detecting malaria. Treatment, to fast track development of new antimalarials, and improve access to ensure all infected people get highly effective drugs.
TB is a global public health problem, responsible for the deaths of 2 million children and young adults annually. Drug resistant strains of TB are emerging and pose a threat even in countries where TB is well controlled, such as Australia. Research undertaken in this CRE will translate into improved treatments, diagnostics and strategies to prevent transmission. The CRE will build capacity for research on TB in our region and provide a legal framework to support public health policy.
A Centre Of Research Excellence In Adolescent Health: Making Health Services Work For Adolescents In A Digital Age
Funder
National Health and Medical Research Council
Funding Amount
$2,496,295.00
Summary
Developmentally appropriate adolescent healthcare must be inter-disciplinary, with sound communication and acknowledging increasing autonomy; not easily accommodated within traditional paediatric and adult models of care. Our diverse team of experts will work with young people, parents, policy makers and service providers to create principles of cost-effective, equitable and accessible healthcare for adolescents, making best use of present-day health services and modern digital technologies.