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Field of Research : Epidemiology
Research Topic : Melanoma
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  • Funded Activity

    Investigating The Utility Of Primary Care Skin Cancer Clinics In Queensland

    Funder
    National Health and Medical Research Council
    Funding Amount
    $187,000.00
    Summary
    Skin cancer is the most common cancer in Australia, with an estimated 375,000 people being treated for some skin cancer in Australia in 2002, and 1462 dying from the disease (mainly from melanoma) in 2001. Australia has the highest rate of skin cancer, both melanoma and non-melanoma is the world. However, if detected early, skin cancer is curable, and the focus of current treatment programs internationally is to detect the disease before it progresses to an advanced stage. A large proportion of .... Skin cancer is the most common cancer in Australia, with an estimated 375,000 people being treated for some skin cancer in Australia in 2002, and 1462 dying from the disease (mainly from melanoma) in 2001. Australia has the highest rate of skin cancer, both melanoma and non-melanoma is the world. However, if detected early, skin cancer is curable, and the focus of current treatment programs internationally is to detect the disease before it progresses to an advanced stage. A large proportion of skin cancers are first detected by the non-medical community. However, due to the two-tiered medical system in Australia, a person first seeks medical opinion from a general practitioner (GP), who acts as a gatekeeper for further treatment from a specialist. Therefore the ability of GPs to be able to discern which lesions require further treatment is crucial, both for the patient, and the financial burden on the health system. A recent development has been the establishment of dedicated primary skin care clinics, which offer open access consultations to the community for the diagnosis and treatment of skin cancers and pigmented lesions. The emergence of these clinics has created much debate in the medical media. Concern has been expressed about the skills of practitioners in these clinics, whilst others argue that sub-specialisation in primary care will lead to improvements in the management of patients. As there is currently no data on the volume, casemix and diagnostic accuracy of these clinics it is difficult to assess the diagnostic ability of skin cancer clinics. This will be the first project to quantify the role of skin clinics in the diagnosis of skin cancer in the community, and in particular their case volume, casemix and diagnostic accuracy, and assess these measures in relation to a comparable sample of general practitioners. Queensland is an ideal location for a study of this type due to its high incidence of both types of skin cancer.
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    Funded Activity

    Cancer Epidemiology In Two Subsets Of The Australian Population: Children & Aboriginal Torres Strait Islander Population

    Funder
    National Health and Medical Research Council
    Funding Amount
    $301,500.00
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    Funded Activity

    Uncoupled Research Fellowship

    Funder
    National Health and Medical Research Council
    Funding Amount
    $715,099.00
    Summary
    Grant Montgomery is a genetic epidemiologist with a special interest in the causes, diagnosis, prevention and treatment of common diseases. His work is focussed primarily on endometriosis and melanoma.
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    Funded Activity

    Exploring The Causal Pathways To Cutaneous Melanoma

    Funder
    National Health and Medical Research Council
    Funding Amount
    $159,171.00
    Summary
    Melanomas are cancers arising from the pigment cells of the skin, and are among the most commonly occurring cancers in this country. Each year, more than 8000 Australians are diagnosed with invasive melanoma, resulting in some 900 deaths annually. Survival from melanoma is high if the disease is detected early (5 yr survival for thin melanomas-94%), however survival rates for thicker tumours are significantly worse, and for metastatic disease, very poor (<10%). Sunlight is the principal facto .... Melanomas are cancers arising from the pigment cells of the skin, and are among the most commonly occurring cancers in this country. Each year, more than 8000 Australians are diagnosed with invasive melanoma, resulting in some 900 deaths annually. Survival from melanoma is high if the disease is detected early (5 yr survival for thin melanomas-94%), however survival rates for thicker tumours are significantly worse, and for metastatic disease, very poor (<10%). Sunlight is the principal factor which causes this disease, although there is increasing evidence that the role of sunlight in causing melanoma is not the same for all people who develop this disease. A new hypothesis proposes that the malignant course of melanomas may reflect their causal origins, with melanomas induced by chronic sunlight exposure perhaps being more aggressive than other melanomas. We will undertake a large study of patients with melanoma to investigate both the causal pathways to melanoma and their influence on markers of tumour aggressiveness. We will capture detailed information about the microscopic appearance of the melanomas from pathologists at the time of diagnosis, and marry this to the information reported by the patients about their past history of sun exposure. When complete, this study will provide new information about the causes of melanoma. Such knowledge is crucial to controlling and preventing this cancer.
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    Funded Activity

    The Australian Study Of Melanoma Of The Eye

    Funder
    National Health and Medical Research Council
    Funding Amount
    $239,692.00
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    Funded Activity

    Improving Skin Cancer Prevention: Motivating Preventive Behaviours Using Knowledge Of Personalised Genomic Risk Of Melanoma

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,041,720.00
    Summary
    The aim of our study is to evaluate whether we can improve the Australian public’s skin cancer prevention behaviours, particularly reducing exposure to ultraviolet (UV) radiation, by giving personalised information about melanoma genetic risk. We will also explore the psycho-social, ethical, and economic implications of receiving this information. The results of our study are likely to influence the future of skin cancer prevention in Australia.
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    Funded Activity

    Computer Imaging For Diagnosis Of Melanoma And Patient Follow-up

    Funder
    National Health and Medical Research Council
    Funding Amount
    $71,676.00
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    Funded Activity

    Determining The Natural History Of Localized High-risk Melanoma And Risk Factors For Melanoma Metastasis

    Funder
    National Health and Medical Research Council
    Funding Amount
    $103,980.00
    Summary
    This PhD thesis aims to describe 2-year survival rates of patients with localised melanoma. We will investigate risk factors and patterns of melanoma spread in patients with high-risk localised lesions. Risk factors for developing ulcerated versus non-ulcerated melanomas will be explored. We aim to describe support service use in melanoma patients in rural, regional and urban areas in Queensland.
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    Funded Activity

    Twin And Family Studies Of Hereditary And Environmental Factors In Melanoma

    Funder
    National Health and Medical Research Council
    Funding Amount
    $502,406.00
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    Funded Activity

    Studies In Cancer Control

    Funder
    National Health and Medical Research Council
    Funding Amount
    $763,409.00
    Summary
    Professor Whiteman is a medical epidemiologist with interests in the causes, prevention and treatment of cancer. His fellowship will be directed towards research focussing on methods for controlling cancers of the skin and oesophagus.
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