Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100018
Funder
Australian Research Council
Funding Amount
$630,000.00
Summary
Purchase of a high resolution Nuclear Magnetic Resonance spectrometer with liquid chromatography module. A high resolution Nuclear Magnetic Resonance spectrometer and liquids separation module will support Tasmanian research of international significance across the biological and medical sciences, chemistry and Tasmanian industries including profiling studies in human health, plant biology, molecular basis of disease and complex mixture analysis.
Selectivity enhancement in separation science using responsive materials. Increasing public demand for quality products from the chemical, pharmaceutical, biotechnology and food industries requires access to innovative methods of chemical analysis. This project will establish a new class of separation materials of enhanced selectivity and resolving power for the fast, sensitive and reliable analysis of these products.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvasc ....Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvascular function and microvascular fitness by using the latest technology to map blood flow routes in muscle under a number of relevant situations. Read moreRead less
Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equat ....Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equations, specifically for monitoring the nutritive fraction of blood flow in muscle by agents and factors relating to health and disease. This technique could be used for screening drugs in the treatment of diseases such as type 2 diabetes and related conditions.Read moreRead less
A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability ....A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability of current drugs and thus significantly shorten the recurrence period. Such new drugs may have broad applicability.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100059
Funder
Australian Research Council
Funding Amount
$350,790.00
Summary
Advanced high resolution biomolecular analysis facility for Tasmania. This project aims to establish an advanced, multi-purpose mass spectrometry platform for high-throughput and targeted biomolecular analysis, including proteomics and metabolomics. The purpose of the project is to provide a centralised state-of-the-art facility that supports research programs in plant science, agricultural research, food safety, animal and human health research and separation science. Potential benefits from th ....Advanced high resolution biomolecular analysis facility for Tasmania. This project aims to establish an advanced, multi-purpose mass spectrometry platform for high-throughput and targeted biomolecular analysis, including proteomics and metabolomics. The purpose of the project is to provide a centralised state-of-the-art facility that supports research programs in plant science, agricultural research, food safety, animal and human health research and separation science. Potential benefits from the project include increased agricultural productivity and food security, improved knowledge of age and injury-related changes in neurophysiology, helping to prevent the extinction of iconic Tasmanian wildlife and the development of advanced micro-electroseparation technologies.Read moreRead less
ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas ....ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas of human health through the regeneration of damaged nerves (eg. in spinal injury) and development of artificial muscles; in renewable energy (plastic solar cells, lightweight batteries and electronic textiles) and in sustainable industries (recovery of precious metals and new corrosion protection technologies).Read moreRead less