Quantitative dynamics of functional magnetic resonance imaging. By modeling and verifying the dynamics of brain activity and blood flow that underlie functional magnetic resonance imaging (fMRI), this project will yield improved scientific outcomes and imaging sensitivity. The new data analysis techniques and technologies that result will yield potentially patentable intellectual property, and will increase the standing of Australia in this rapidly developing field, including via links being bu ....Quantitative dynamics of functional magnetic resonance imaging. By modeling and verifying the dynamics of brain activity and blood flow that underlie functional magnetic resonance imaging (fMRI), this project will yield improved scientific outcomes and imaging sensitivity. The new data analysis techniques and technologies that result will yield potentially patentable intellectual property, and will increase the standing of Australia in this rapidly developing field, including via links being built to leading international workers. The National Research Priority Goals of Frontier Technologies, Breakthrough Science, Smart Information Use, and Promoting an Innovation Economy will thus be advanced.Read moreRead less
Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast ....Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast cancer and contribute to the development of an automated diagnostic method, with the possibility of its application to other diseases. The project will also involve members of the regional community, train regional scientists and provide synchrotron experience for Australian scientists in time for Australia's first synchrotron.Read moreRead less
Material boundaries in ultrasonics: New methods and in vitro studies in biomedical phantoms. Ultrasound is an indispensable part of healthcare worldwide. The next wave of applications will see ultrasound pulses used to closely probe suspected disease sites and to directly manipulate bioactive agents. For safe and effective use of such techniques it is essential to know the ultrasound field at the disease site. This project will develop simulation methods to achieve the fast, accurate and case-sp ....Material boundaries in ultrasonics: New methods and in vitro studies in biomedical phantoms. Ultrasound is an indispensable part of healthcare worldwide. The next wave of applications will see ultrasound pulses used to closely probe suspected disease sites and to directly manipulate bioactive agents. For safe and effective use of such techniques it is essential to know the ultrasound field at the disease site. This project will develop simulation methods to achieve the fast, accurate and case-specific results required. Community healthcare will benefit, through better diagnostic capabilities and customized treatment. Australia is well placed to profit further from this research, in view of the growing worldwide demand for more sophisticated, knowledge-based techniques in medicine.Read moreRead less
The effect of vessel wall structures on ultrasonic flow velocity measurements. The flow velocity within a nearly cylindrical vessel is often measured using an external ultrasound transducer via the Doppler principle. Thick vessel walls may present acoustically mismatched structures. This project aims to determine how such walls redistribute the energy in an interrogating ultrasound beam, and how this in turn affects the measurement of flow velocities. This is a fundamental issue, especially imp ....The effect of vessel wall structures on ultrasonic flow velocity measurements. The flow velocity within a nearly cylindrical vessel is often measured using an external ultrasound transducer via the Doppler principle. Thick vessel walls may present acoustically mismatched structures. This project aims to determine how such walls redistribute the energy in an interrogating ultrasound beam, and how this in turn affects the measurement of flow velocities. This is a fundamental issue, especially important in vascular disease where blood flow and blood vessels are affected by wall irregularities and lesions. The new knowledge generated by this project will have practical importance and, by identifying achievable outcomes, potentially major cost savings, in medical ultrasound.Read moreRead less
Studies of turbulence and coherent structures in quasi two-dimensional plasmas and fluids. One of the most celebrated but least understood complex systems in nature is turbulent flow. This cross-disciplinary project aims to contribute to basic scientific knowledge of a class of turbulent flows, known as quasi two-dimensional fluids, that typically exhibit self-organizing properties, stable sheared flow, and relatively weak dissipation. The significance lies in the proposed testing, by modelling ....Studies of turbulence and coherent structures in quasi two-dimensional plasmas and fluids. One of the most celebrated but least understood complex systems in nature is turbulent flow. This cross-disciplinary project aims to contribute to basic scientific knowledge of a class of turbulent flows, known as quasi two-dimensional fluids, that typically exhibit self-organizing properties, stable sheared flow, and relatively weak dissipation. The significance lies in the proposed testing, by modelling and simulation studies, of the well-grounded hypothesis that suppression of turbulence by sheared flow is a universal phenomenon in such fluids, and that it can be exploited to control transport of fluid constituents. Applications of this new knowledge will be developed.Read moreRead less
The mathematics of cold quantum matter. Ongoing advances in the experimental realisation of ultracold quantum matter play a leading role in the international effort towards the eventual realisation of quantum technology. This research project aims to build on and develop Australia's mathematical research strengths to explore and describe the enabling physics of cold quantum matter. This approach will further consolidate and enhance Australia's leadership in quantum science. The program of fundam ....The mathematics of cold quantum matter. Ongoing advances in the experimental realisation of ultracold quantum matter play a leading role in the international effort towards the eventual realisation of quantum technology. This research project aims to build on and develop Australia's mathematical research strengths to explore and describe the enabling physics of cold quantum matter. This approach will further consolidate and enhance Australia's leadership in quantum science. The program of fundamental research will also contribute to training mathematically talented students in a rapidly advancing area with the capacity to contribute to a wide range of problems, including the emerging technology of quantum devices.Read moreRead less
Quantum Simulations with Dilute Gas Bose Einstein Condensates. Fundamental scientific research, such as we propose, is an important contributor to the long term wealth and well being of the Nation. It shapes our culture, our ways of thinking, and our beliefs. It also contributes directly, and in the shorter term, through the technology development that accompanies scientific research at the frontiers of knowledge. The students participating in this research will develop skills in innovation, int ....Quantum Simulations with Dilute Gas Bose Einstein Condensates. Fundamental scientific research, such as we propose, is an important contributor to the long term wealth and well being of the Nation. It shapes our culture, our ways of thinking, and our beliefs. It also contributes directly, and in the shorter term, through the technology development that accompanies scientific research at the frontiers of knowledge. The students participating in this research will develop skills in innovation, intellectual property management, and commercialisation - all of which are critical to the Nation's future.Read moreRead less
Quantum correlations in ultra-cold Fermi gases. The field of ultra-cold Fermi gases provides a unique opportunity to develop and test theoretical methods for novel experimental environments of exceptional purity and simplicity. This improved understanding will have potential applications in many fields, ranging from the astrophysics of neutron stars to condensed matter systems such as superconductors or nanostructures. Just as importantly, the project will develop linkages with world leading the ....Quantum correlations in ultra-cold Fermi gases. The field of ultra-cold Fermi gases provides a unique opportunity to develop and test theoretical methods for novel experimental environments of exceptional purity and simplicity. This improved understanding will have potential applications in many fields, ranging from the astrophysics of neutron stars to condensed matter systems such as superconductors or nanostructures. Just as importantly, the project will develop linkages with world leading theoretical groups, which will greatly aid research student education. There are direct applications to experiments on molecule formation with ultra-cold fermions in the ARC Centre of Excellence for Quantum-Atom Optics.Read moreRead less
Singular photonics: twisted light and optical vortices.
This project will help to establish and support a world-leading research team in Australia in the field of singular photonics and the physics of twisted light; it will help to return the leading positions of the Australian physics in the field of singular optics, and it will initiate a design of a novel generation of photonic devices operating with vortex beams. The project will promote this field in order to enhance its rapid development ....Singular photonics: twisted light and optical vortices.
This project will help to establish and support a world-leading research team in Australia in the field of singular photonics and the physics of twisted light; it will help to return the leading positions of the Australian physics in the field of singular optics, and it will initiate a design of a novel generation of photonic devices operating with vortex beams. The project will promote this field in order to enhance its rapid development and facilitate the emergence of novel technologies in Australia; it will be combined with an extensive collaboration with top overseas groups attracting strong interest from industry.Read moreRead less
Physical properties of exactly solved quantum spin systems. Progress in understanding quantum spin systems in condensed matter physics can be greatly enhanced by the knowledge and understanding obtained from exactly solved models. This project will apply new techniques from the theory of exactly solved models to calculate the magnetic and thermal properties of quantum spin systems. The outcomes will include progress at the forefront of theoretical physics, with direct comparison with experimenta ....Physical properties of exactly solved quantum spin systems. Progress in understanding quantum spin systems in condensed matter physics can be greatly enhanced by the knowledge and understanding obtained from exactly solved models. This project will apply new techniques from the theory of exactly solved models to calculate the magnetic and thermal properties of quantum spin systems. The outcomes will include progress at the forefront of theoretical physics, with direct comparison with experimental results and strong predictive power for new experiments. The project will establish strong research links between Australia and Japan.Read moreRead less