A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability ....A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability of current drugs and thus significantly shorten the recurrence period. Such new drugs may have broad applicability.Read moreRead less
Investigation into flow over complex topography and escarpments for wind turbine siting using experimental and computational methods. This project will improve national capability to optimise power production from wind turbine farms in complex terrain by improving the understanding of the flow regime. By better understanding separated regions and the turbulent structures within these regions power production can be optimised and fatigue risks associated with turbine positioning in complex sites ....Investigation into flow over complex topography and escarpments for wind turbine siting using experimental and computational methods. This project will improve national capability to optimise power production from wind turbine farms in complex terrain by improving the understanding of the flow regime. By better understanding separated regions and the turbulent structures within these regions power production can be optimised and fatigue risks associated with turbine positioning in complex sites can be reduced. This will improve confidence in wind farm site assessment techniques and consequently reduce economic risks associated with current wind farm viability assessments. By increasing national capacity to generate clean energy stationary energy emissions can be reduced. This project will also deliver high calibre graduates that will be potential future industry leaders.Read moreRead less
How does orography enhance precipitation in Australian wintertime storms? This project aims to employ targeted field observations, numerical simulations and new satellite capabilities to identify the dynamical and microphysical mechanisms that enhance and redistribute precipitation across the alpine regions of south eastern Australia and Tasmania. These observations will be used to evaluate operational numerical weather simulations specifically focusing on quantitative precipitation forecasts an ....How does orography enhance precipitation in Australian wintertime storms? This project aims to employ targeted field observations, numerical simulations and new satellite capabilities to identify the dynamical and microphysical mechanisms that enhance and redistribute precipitation across the alpine regions of south eastern Australia and Tasmania. These observations will be used to evaluate operational numerical weather simulations specifically focusing on quantitative precipitation forecasts and estimates. The observations will also be used to extend known biases in the national gridded precipitation analysis that are a result of the complex mountain terrain. This identification of the physical processes that enhance and redistribute precipitation over the alpine regions across south east Australia and Tasmania will lead to better precipitation estimates and forecasts and better water management.Read moreRead less
The neural effects of torture. Torture affects millions of people and causes much long-term psychological harm. This project aims to identify the effects that torture has on the brain by studying torture survivors in the context of a range of brain imaging technologies that will lead to development of a model of the neural effects of torture to guide better treatments.
Development of an immune enhancing vaccine to protect Tasmanian devils against a contagious cancer. The iconic Tasmanian devil is threatened with extinction from a uniformly fatal transmissible facial cancer. Our team has shown in proof of concept that the cancer cells can be recognised by the devil immune system. This project will develop and test a vaccine against the tumour, which will ultimately protect devils in the wild.
Precipitation in wintertime storms across southeast Australia, Tasmania and the Southern Ocean. The pristine conditions and strong wind-shear over the Southern Ocean affect the formation of precipitation in clouds over the region, which is vital to the water supply of southeastern Australia and Tasmania. This project will evaluate and improve the ability to simulate this precipitation, which will lead to better water resource management.
Creating a national time and frequency network for Australia. This project will develop the means to distribute accurate time and frequency across the Australian continent via an optical fibre network. This network will meet the needs of future telecommunications, science and astronomy projects including the Australian bid for the Square Kilometre Array radio-astronomy project.