Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of posit ....Positrons in biosystems. This project aims to improve our understanding of the damage processes in Positron Emission Tomography (PET). PET is a widely used medical imaging technique, but there are gaps in our understanding of the underlying interactions, in particular in the case of the radiation damage induced during the process. By using new models incorporating accurate descriptions of interactions processes, verified by experimental measurement, this project will develop a new model of positron transport in PET. The project will allow validation of predictions from the model by undertaking experiments in liquid water.Read moreRead less
Disruptive approaches to biological sensing. Optical fibre-based biosensors have the potential to transform our ability to monitor our environment, protect our nation's assets and safeguard our citizens, and to offer improved clinical diagnostics and food quality control by creating tools that can detect biomolecules in real-time within complex samples. To fulfil this mission, we propose to develop new fibre-based sensing architectures for sensing biomolecules that have the potential to be sensi ....Disruptive approaches to biological sensing. Optical fibre-based biosensors have the potential to transform our ability to monitor our environment, protect our nation's assets and safeguard our citizens, and to offer improved clinical diagnostics and food quality control by creating tools that can detect biomolecules in real-time within complex samples. To fulfil this mission, we propose to develop new fibre-based sensing architectures for sensing biomolecules that have the potential to be sensitive, selective, fast and compact.Read moreRead less
Special Research Initiatives - Grant ID: SR0354734
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving h ....The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving health care and reducing health care costs. To be successful, a device must include all relevant disciplines in the research, development and testing phases. This network will bring together these groups, promoting knowledge sharing and cross-disciplinary investigations that illuminate current device limitations and potential solutions.Read moreRead less
Plasma-soft tissue interactions: advancing a new era of plasma technologies. This project aims to develop the prerequisite knowledge to underpin new plasma technologies. Specifically, the project plans to provide new insight into the interaction between ionised gas plasma jets and biological soft tissue. It plans to use advanced analytical techniques and modelling simulations to investigate the physics of the plasma jet and processes occurring at the jet–tissue interface. It also plans to use (b ....Plasma-soft tissue interactions: advancing a new era of plasma technologies. This project aims to develop the prerequisite knowledge to underpin new plasma technologies. Specifically, the project plans to provide new insight into the interaction between ionised gas plasma jets and biological soft tissue. It plans to use advanced analytical techniques and modelling simulations to investigate the physics of the plasma jet and processes occurring at the jet–tissue interface. It also plans to use (bio)engineered tissue targets, chemical, biological and cellular assays to probe the transport and effects of plasma reactive species deep within tissue. This new knowledge would enable the development of new plasma sources and protocols for applications in health, medicine, biotechnology and manufacturing.Read moreRead less
Transformational diagnostics. Australia has established world-leading capabilities in optical fibres and surface science that, when brought together, have the potential to transform applications that require non-invasive, real-time and/or portable biological detection tools. We propose a novel and ambitious suite of projects that bring together these capabilities with experts in reproductive health, forensics and explosives to solve pressing problems in each of these areas that have the promise ....Transformational diagnostics. Australia has established world-leading capabilities in optical fibres and surface science that, when brought together, have the potential to transform applications that require non-invasive, real-time and/or portable biological detection tools. We propose a novel and ambitious suite of projects that bring together these capabilities with experts in reproductive health, forensics and explosives to solve pressing problems in each of these areas that have the promise to develop into new industries for Australia as well as to explore rich science opportunities at the boundaries of these disciplines.Read moreRead less
Development of modal control systems for adaptive optics. This project will develop a simple, robust and low-cost modal servo system for dynamic control and correction of the propagation and focussing properties of light beams. This new system will incorporate a novel optical sensor, which will be developed in this project, and a new optical corrector being developed at the University of Durham. Currently available astronomical adaptive-optics systems have produced excellent results but are expe ....Development of modal control systems for adaptive optics. This project will develop a simple, robust and low-cost modal servo system for dynamic control and correction of the propagation and focussing properties of light beams. This new system will incorporate a novel optical sensor, which will be developed in this project, and a new optical corrector being developed at the University of Durham. Currently available astronomical adaptive-optics systems have produced excellent results but are expensive and complicated. A low-cost alternative will dramatically increase the use of adaptive optics in industrial, environmental and medical applications. The compensation of distortions in low-cost optical atmospheric sensors will be demonstrated.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100001
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation ....Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation at sub-micron scales and cryogenic temperatures, under bio-simulated environments, down to single pixel resolution, with parallel imaging and spectroscopy, and of fluids and biomaterials. The instrumentation will include cryogenic sub-micron photoluminescence and micro-Raman spectroscopy, single pixel optical and dark field spectroscopy, continuous wave terahertz time-domain spectroscopy, wide wavelength microscopic spectroscopy, and temperature-jump kinetics spectroscopy. It is expected that these complementary instruments will accelerate research in materials and devices for plasmonics, nanoelectronics, biomedicine, biochemistry, security, and forensic science.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
Investigation of three dimensional terahertz computed tomography for biomedical applications. Terahertz (T-ray) imaging is an exciting newly emerging technology that can perform safe, non-invasive, imaging and chemical sensing at the same time. This research aims to achieve an advance in terahertz imaging by using advanced methods that will enhance our ability to achieve accurate detection of diseased tissue in vivo. Socio-economic benefits to Australia include: (i) contributions to terahertz sy ....Investigation of three dimensional terahertz computed tomography for biomedical applications. Terahertz (T-ray) imaging is an exciting newly emerging technology that can perform safe, non-invasive, imaging and chemical sensing at the same time. This research aims to achieve an advance in terahertz imaging by using advanced methods that will enhance our ability to achieve accurate detection of diseased tissue in vivo. Socio-economic benefits to Australia include: (i) contributions to terahertz systems, enhancing Australia's reputation for cutting-edge research; (ii) international collaboration will be strengthened; (iii) results will potentially lead to commercialisation opportunities; (iv) the outcomes will ultimately impact on improving terahertz imaging in quality control, medical diagnosis, and detection for national security.Read moreRead less
A single vaccine for influenza and pneumonia. Influenza and bacterial pneumonia collaborate to kill millions of people each year. This project aims to develop a single vaccine that will provide long-lasting protection against both influenza and pneumonia.