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Research Topic : Medical genomics, Molecular genetics
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  • Funded Activity

    The Economic And Social Impacts Of Genetic Sequencing For Intellectual Disability

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,263,576.00
    Summary
    In this project we will quantify the social and financial costs to families of severe intellectual disability that is genetic in origin. We will assess these impacts in terms of poorer carer health, relationship breakdown, lost income and risk of poverty, as well as increased dependence on government, particularly on welfare payments, and reduced personal income tax paid. We will then determine the extent to which modern clinical genomics can contribute to ameliorating these impacts.
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    Understanding The Sources Of Campylobacter In Australia

    Funder
    National Health and Medical Research Council
    Funding Amount
    $546,720.00
    Summary
    Campylobacter is a key cause of foodborne disease in Australia, with rates of illness amongst the highest in the world. Our project brings together academic, government and industry partners to harness new genetic techniques to better identify sources and risk factors for Campylobacter infection. The project will assist health agencies to include genomics in public health, with findings directly informing government policies and industry practices to minimise disease caused by Campylobacter.
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    Funded Activity

    An Evidence Based Framework For Establishing Public Health Microbial Genomics In Australia

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,413,093.00
    Summary
    Microbial genomics is a powerful laboratory tool to characterise human pathogens at the highest level, allowing greater understanding of the source and spread of pathogens that infect humans. In this project, through close links with the Victorian Government, we will determine how this exciting new technology can best be applied to prevent the spread of high risk human pathogens, and inform public health action.
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    Funded Activity

    Notifications To The Australian Health Practitioner Regulation Agency: Identifying ‘hot Spots’ Of Risk To Help Improve The Quality And Safety Of Healthcare

    Funder
    National Health and Medical Research Council
    Funding Amount
    $276,072.00
    Summary
    Health practitioners with performance, health or conduct concerns can present a serious risk to patients. Yet we lack reliable methods for identifying these practitioners at an early stage. Each year the Australian Health Practitioner Regulation Agency receives 1,000s of notifications about individual practitioners. We will use this data to identify “hot spots” of risk among different groups of practitioners and help target interventions to support practitioners and protect patients from harm.
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    Funded Activity

    The Effectiveness, Acceptability And Cost Effectiveness Of The 'BALatrine'

    Funder
    National Health and Medical Research Council
    Funding Amount
    $792,169.00
    Summary
    We will undertake an intervention trial to assess the effectiveness of the “BALatrine” (a novel latrine) and hygiene education in the prevention of intestinal worms in Indonesia. This will provide an evidence base for translation of the intervention into public health policy and practice in Indonesia, the Asian region and beyond.
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    Funded Activity

    Evidence Innovation: Transforming The Efficiency Of Systematic Review

    Funder
    National Health and Medical Research Council
    Funding Amount
    $928,417.00
    Summary
    Australia invests considerable resources developing reliable summaries of research evidence to understand the benefits and risks of drugs and health programs. We will use information technologies and ‘crowdsourcing’ to improve the production of evidence summaries, evaluate this approach in a randomised study, and facilitate implementation throughout Australia. This will improve the translation of research into health practice and policy, reducing research waste and improving health outcomes.
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    Funded Activity

    Models And Quality Of Genetic Health Services For Aboriginal And Torres Strait Islander People

    Funder
    National Health and Medical Research Council
    Funding Amount
    $351,240.00
    Summary
    Genetic health services are playing an increasingly important role in improving human health. Aboriginal people are underrepresented in such services despite a higher prevalence of a number of genetically determined conditions and evidence of willingness to access these services. Our grant will inform the development of effective models of genetic health service provision for Aboriginal people. This will improve health equity both now and in the future.
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    Funded Activity

    Evaluating The Effectiveness Of A Strategy To Increase The Adoption Of Best Evidence Practice.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $800,532.00
    Summary
    The health-care system does not consistently implement best-evidence practice, preventing the community from achieving optimal health outcomes. Effective strategies to reduce evidence practice gaps are now required. In stroke care, thrombolysis is the most powerful and cost-effective therapy but is delivered to less than 5% of stroke patients. This study would be the first to rigorously test the effectiveness of a modified Breakthrough Series approach in achieving best evidence stroke care.
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    Funded Activity

    A Multi-centre RCT To Prevent Secondary Falls In Older People Presenting To The Emergency Department With A Fall

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,534,471.00
    Summary
    Falls are a leading cause for presentation to Emergency Departments (EDs) by older patients. More than 50% who present to ED with a fall injury have fallen in the previous year. RESPOND is an innovative post-ED discharge program designed to reduce secondary falls in older people. RESPOND extends current falls prevention research and practice by incorporating patient-centred education with behaviour change strategies proven to be effective in the secondary prevention of cardiovascular events.
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    Funded Activity

    Validation Of The Four Hour Rule In Australia

    Funder
    National Health and Medical Research Council
    Funding Amount
    $687,000.00
    Summary
    The purpose of this partnership project is to assess the impact of the four-hour rule policy in reducing access block and its effects of Emergency Department (ED) overcrowding on patients before and after its implementation. We will examine the trends and characteristics of patients under the policy in WA hospitals and compare them with similar patients not under the policy. This is a unique opportunity due to a natural experiment occurring in Australia with implications at the national and inte .... The purpose of this partnership project is to assess the impact of the four-hour rule policy in reducing access block and its effects of Emergency Department (ED) overcrowding on patients before and after its implementation. We will examine the trends and characteristics of patients under the policy in WA hospitals and compare them with similar patients not under the policy. This is a unique opportunity due to a natural experiment occurring in Australia with implications at the national and international levels.
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