Clinical Application Of Genomic Approaches For Cancer
Funder
National Health and Medical Research Council
Funding Amount
$707,370.00
Summary
Cancer is the cause of 1 in 8 deaths worldwide. Cancer occurs due to errors or mutations in the DNA of normal cells. I will identify the mutations in tumour cells, which will tell us: i) How the tumour started and grew ii) How to treat the tumour and kill the cancer The work involves a variety of cancer types including mesothelioma, melanoma, oesophageal and breast cancer. The overall aim is to apply some of the research findings or approaches into patient care to improve patient survival.
Computational Approaches To Making Sense Of Cancer -omics Data
Funder
National Health and Medical Research Council
Funding Amount
$706,370.00
Summary
Evolution is a hallmark of cancer. It underlies tumorigenesis, metastasis, disease progression, the emergence of drug resistance, and patient death. My research will develop the essential bioinformatics methods and computational models to understand cancer evolution using -omics data, and apply these to discover the molecular mechanisms that cause complex genome rearrangements; investigate the evolution of advanced melanoma; and translate our tools and discoveries into the clinical setting.
Innovations In Cancer Imaging And Targeted Radiotherapy To Improve Human Health
Funder
National Health and Medical Research Council
Funding Amount
$926,980.00
Summary
Through a process of discovery, development and investigation we will create medical devices and methods to improve cancer imaging and targeted radiotherapy. Successful completion of this program will directly impact on the treatment and lives of Australian cancer patients in the foreseeable future.This program will substantially build research capacity and productivity within Australia, raise Australia’s profile in cancer research and foster international collaboration.