Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100122
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
Returning WA Rapid Acquisition Fluorescent Microscopy to the cutting edge. The equipment proposal aims to establish West Australia's only super-rapid-speed, high throughput confocal microscopy facility. The technology will provide researchers in biotechnology, medicine, environmental biology and agriculture with contemporary state-of-art opportunities to analyse living cells and/or large-area tissue specimens in three-dimensions with the highest possible speed and high-resolution. West Australia ....Returning WA Rapid Acquisition Fluorescent Microscopy to the cutting edge. The equipment proposal aims to establish West Australia's only super-rapid-speed, high throughput confocal microscopy facility. The technology will provide researchers in biotechnology, medicine, environmental biology and agriculture with contemporary state-of-art opportunities to analyse living cells and/or large-area tissue specimens in three-dimensions with the highest possible speed and high-resolution. West Australia hosts 1 twelve-year old historic rapid-acquisition confocal microscope that is heavily subscribed, no longer manufactured and prone to regular, prolonged, costly breakdowns. Accessing high-speed confocal systems in other states is not a viable option putting WA-based researchers at a significant disadvantage.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668435
Funder
Australian Research Council
Funding Amount
$1,300,000.00
Summary
Biomedical Engineering Sensing and Imaging Facility. The sensing and imaging facility will be the only national facility for leading engineering and medical researchers to undertake multidiscipline research into live and model biological systems. The facility will capture and combine existing strengths in these fields in Melbourne. This will provide new insights into the physiology of human, animal and plant systems and the development of preventive and curative strategies for disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239218
Funder
Australian Research Council
Funding Amount
$340,000.00
Summary
Proteomics facility for biotechnology research in WA. The aim of this application is to establish a fully functional proteomics facility to underpin the future research of many groups in four WA institutions. While molecular biological research has thus far concentrated on molecular genetics, it is now vital to directly examine the patterns of proteins expressed by cells to understand their molecular mechanisms. Individual WA researchers have already ventured into proteomics, utilising facilit ....Proteomics facility for biotechnology research in WA. The aim of this application is to establish a fully functional proteomics facility to underpin the future research of many groups in four WA institutions. While molecular biological research has thus far concentrated on molecular genetics, it is now vital to directly examine the patterns of proteins expressed by cells to understand their molecular mechanisms. Individual WA researchers have already ventured into proteomics, utilising facilities located elsewhere in Australia. The reliance on other groups to conduct their proteomics, which are rapidly becoming basic techniques for competitive molecular biological research, is a serious obstacle to biotechnological research in WA.Read moreRead less
Implementing and evaluating the impact of the Carer Support Needs Assessment Tool (CSNAT) in community palliative care. The support needs of family caregivers at end of life will be assessed using a comprehensive tool and addressed by service providers to improve carers' psychological and physical wellbeing, carer burden, bereavement outcomes and the likelihood of the patient achieving their preferred place of death.
Ecophysiology of water-holding frogs in the Australian arid-zone. Water-holding frogs of arid-zone Australia have an Aboriginal heritage and cultural significance, but many aspects of their natural history, physiology and reproduction are poorly known or documented. We will examine behaviour, physiology, endocrinology, reproductive cycles and movements for these frogs (Cyclorana, Neobatrachus, Notaden, Heleioporus) while active on the surface, and cocoon formation, subterranean movements and dyn ....Ecophysiology of water-holding frogs in the Australian arid-zone. Water-holding frogs of arid-zone Australia have an Aboriginal heritage and cultural significance, but many aspects of their natural history, physiology and reproduction are poorly known or documented. We will examine behaviour, physiology, endocrinology, reproductive cycles and movements for these frogs (Cyclorana, Neobatrachus, Notaden, Heleioporus) while active on the surface, and cocoon formation, subterranean movements and dynamics of water exchange with the soil, metabolic depression, muscle ATP energetics, endocrinology and aspects of reproduction while aestivating underground. We have the expertise and prior experience to accomplish all aspects of the proposed studies.Read moreRead less
Reproductive technologies for the conservation of a critically endangered marsupial, the Gilberts potoroo. The Gilberts potoroo is currently Australia's most endangered mammal (population total is less than 40). Natural breeding in captivity has not been successful so reproductive technology, especially artificial insemination, will be developed contribute to the survival of the species. This will involve detailed testing of techniques for semen collection and preservation, oestrus detection an ....Reproductive technologies for the conservation of a critically endangered marsupial, the Gilberts potoroo. The Gilberts potoroo is currently Australia's most endangered mammal (population total is less than 40). Natural breeding in captivity has not been successful so reproductive technology, especially artificial insemination, will be developed contribute to the survival of the species. This will involve detailed testing of techniques for semen collection and preservation, oestrus detection and artificial insemination, initially with the closely related Long-nosed potoroo. Once reliable protocols are developed, they will be applied to the Gilberts potoroo. If successful, this will be the first application of artificial insemination to increasing the numbers of a threatened species of marsupial in Australia.Read moreRead less
The impact of water logging on mitochondrial metabolism in leaves and roots of Grey poplar. Water logging and flooding are seasonal occurrences in a variety of environments. These events cause various damage to environments, including damage to plants. The damage to plants has traditionally been associated with annuals, such as various crop species. However larger plants, i.e. trees, are also very susceptible to water-logging and flooding. As it can take from several years to decades for tress t ....The impact of water logging on mitochondrial metabolism in leaves and roots of Grey poplar. Water logging and flooding are seasonal occurrences in a variety of environments. These events cause various damage to environments, including damage to plants. The damage to plants has traditionally been associated with annuals, such as various crop species. However larger plants, i.e. trees, are also very susceptible to water-logging and flooding. As it can take from several years to decades for tress to be established it is important to understand how trees can withstand water-logging and flooding. As tree plantation are uses for commercial and environmental purposes this knowledge will be useful to a broad spectrum of users in the community.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120101562
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Quantifying the contribution of leaf vein networks to the leaf economics spectrum in native and agricultural species. Using a combination of eco-physiological and geometric measures this project will evaluate the influence of leaf vein networks on leaf economics. It is expected that this work will identify vein investment and network design as major sources of variability underlying species adaptive strategies, and the global leaf economics spectrum as a whole.
Indian Sandalwood: genetic and oil diversity, and oil biochemistry of the Australian germplasm collection. The main aim is to improve the commerciality of the sandalwood industry in tropical Australia through smarter tree selection and breeding by development of knowledge of oil quality and quantity, oil biochemistry and DNA marker-assisted selection of the germplasm collection available in Australia.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100021
Funder
Australian Research Council
Funding Amount
$2,168,000.00
Summary
Australian Metabolic Phenotyping Centre (AMPC). This project aims to establish a centre for targeted and exploratory metabolic phenotyping. Metabolic phenotyping quantitatively measures the precursors, intermediates and products of metabolism interacting within a biological system. This project will use high-resolution spectrometry and spectroscopy to generate comprehensive, multi-parameter metabolite data sets for biological samples at the population level, at unprecedented throughput and low c ....Australian Metabolic Phenotyping Centre (AMPC). This project aims to establish a centre for targeted and exploratory metabolic phenotyping. Metabolic phenotyping quantitatively measures the precursors, intermediates and products of metabolism interacting within a biological system. This project will use high-resolution spectrometry and spectroscopy to generate comprehensive, multi-parameter metabolite data sets for biological samples at the population level, at unprecedented throughput and low cost, to address biological and biomedical research needs. This project is expected to make Australian scientists globally competitive in the life sciences including biological, clinical and biomedical, plant and crop sciences, analytical chemistry, toxicology, agriculture, wildlife conservation and sports science, and to drive advances in the data sciences for systems biology.Read moreRead less