Genetic control of flowering and photoperiodism in pea. The timing of flowering in many plant species is strongly influenced by photoperiod. The mechanisms by which photoperiod controls flowering will be investigated using the garden pea as a model system. New pea mutants impairing photoperiod responses will be identified and characterized, and photoperiod response genes from Arabidopsis will be mapped and used for expression studies in pea. This work will provide important new information about ....Genetic control of flowering and photoperiodism in pea. The timing of flowering in many plant species is strongly influenced by photoperiod. The mechanisms by which photoperiod controls flowering will be investigated using the garden pea as a model system. New pea mutants impairing photoperiod responses will be identified and characterized, and photoperiod response genes from Arabidopsis will be mapped and used for expression studies in pea. This work will provide important new information about the physiological roles of the Arabidopsis genes and the molecular identity of the pea genes. It will add to our knowledge of how flowering is regulated, and this will have important agronomic applications.Read moreRead less
Comparative genetics of flowering and photoperiod responsiveness in legumes. The results from this project will add to our basic knowledge of the way in which environmental factors influence flowering in plants. The timing and duration of flowering is a critical determinant of yield for many crop species, and of market value for many ornamental species. A better understanding of the basic genetics and physiology of flowering will thus be relevant for plant breeders and horticulturalists seeking ....Comparative genetics of flowering and photoperiod responsiveness in legumes. The results from this project will add to our basic knowledge of the way in which environmental factors influence flowering in plants. The timing and duration of flowering is a critical determinant of yield for many crop species, and of market value for many ornamental species. A better understanding of the basic genetics and physiology of flowering will thus be relevant for plant breeders and horticulturalists seeking to modify flowering responses to suit particular production strategies, and will help to maintain the strong position of Australia as a world leader in applied aspects of plant/environment interactions. It will also strengthen the international reputation of Australia for high-quality basic research in plant development.Read moreRead less
Mobile signals and the environmental control of flowering - a comparative genetic analysis. The results from this project will add to our basic knowledge of the way in which environmental factors influence flowering in plants. The timing and duration of flowering is a critical determinant of yield for many crop species, and of market value for many ornamental species. A better understanding of the basic genetics and physiology of flowering will thus be relevant for plant breeders and horticultu ....Mobile signals and the environmental control of flowering - a comparative genetic analysis. The results from this project will add to our basic knowledge of the way in which environmental factors influence flowering in plants. The timing and duration of flowering is a critical determinant of yield for many crop species, and of market value for many ornamental species. A better understanding of the basic genetics and physiology of flowering will thus be relevant for plant breeders and horticulturalists seeking to modify flowering responses to suit particular production strategies, and will help to maintain the strong position of Australia as a world leader in applied aspects of plant/environment interactions. It will also strengthen the international reputation of Australia for high-quality basic research in plant development .Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100018
Funder
Australian Research Council
Funding Amount
$630,000.00
Summary
Purchase of a high resolution Nuclear Magnetic Resonance spectrometer with liquid chromatography module. A high resolution Nuclear Magnetic Resonance spectrometer and liquids separation module will support Tasmanian research of international significance across the biological and medical sciences, chemistry and Tasmanian industries including profiling studies in human health, plant biology, molecular basis of disease and complex mixture analysis.
Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvasc ....Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvascular function and microvascular fitness by using the latest technology to map blood flow routes in muscle under a number of relevant situations. Read moreRead less
Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equat ....Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equations, specifically for monitoring the nutritive fraction of blood flow in muscle by agents and factors relating to health and disease. This technique could be used for screening drugs in the treatment of diseases such as type 2 diabetes and related conditions.Read moreRead less
Molecular pathways controlling light-regulated development in legumes. Legumes are widely grown as forage and grain crops and make a substantial contribution to the Australian economy. Light is an important determinant of plant architecture and productivity and we need to know more about how development is regulated by light in this important plant group. The natural light environment faced by plants is complex and varies with crop density, season and time of day. Understanding the interaction o ....Molecular pathways controlling light-regulated development in legumes. Legumes are widely grown as forage and grain crops and make a substantial contribution to the Australian economy. Light is an important determinant of plant architecture and productivity and we need to know more about how development is regulated by light in this important plant group. The natural light environment faced by plants is complex and varies with crop density, season and time of day. Understanding the interaction of photoreceptors and plant hormones in the control of growth is vital for manipulating crops to meet changing agronomic requirements. Training of students in state-of-the art techniques and the generation of new germplasm for use by other researchers and plant breeders will be other significant outcomes of the project.Read moreRead less
Flexibility in the timing of parturition: the key to viviparity in lizards? Embryos of viviparous lizards usually gain adequate nutrients from yolk. Why then has placentotrophy evolved in some species, and what new opportunities has it opened up? The answer may lie in the advantages gained from flexibility in the timing of birth, made possible by supplementary transfer of storage lipids to embryos during gestation. We argue that this provides a pivotal opportunity for evolutionary divergence: so ....Flexibility in the timing of parturition: the key to viviparity in lizards? Embryos of viviparous lizards usually gain adequate nutrients from yolk. Why then has placentotrophy evolved in some species, and what new opportunities has it opened up? The answer may lie in the advantages gained from flexibility in the timing of birth, made possible by supplementary transfer of storage lipids to embryos during gestation. We argue that this provides a pivotal opportunity for evolutionary divergence: some alpine species exploit flexible parturition; other species replace optional placentotrophy with obligate transfer. Our unique experimental approach, using two well-researched clades of viviparous skinks, will result in new testable hypotheses about the evolution of viviparity.Read moreRead less
Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge ....Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge regarding the function of the CNS and deliver complex human cellular systems, that have both discovery and commercial applications.
Benefit: These platforms will have subsequent application revealing the mechanisms underlying numerous neurological diseases, with capacity to upscale for rapid drug screening.
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Revealing Enigma of Salt Bladders to Help Crops Cope with Salinity. In this project, the key transport systems mediating salt sequestration in halophytes are planned to be characterised and linked with cell genetic and metabolic profiles. Salinity is a major environmental hurdle affecting crop production around the world. Halophytes (naturally salt-loving plants) use specialised structures, called salt bladders, to sequester excessive salt outside their metabolically active parts. This feature i ....Revealing Enigma of Salt Bladders to Help Crops Cope with Salinity. In this project, the key transport systems mediating salt sequestration in halophytes are planned to be characterised and linked with cell genetic and metabolic profiles. Salinity is a major environmental hurdle affecting crop production around the world. Halophytes (naturally salt-loving plants) use specialised structures, called salt bladders, to sequester excessive salt outside their metabolically active parts. This feature is not utilised by crops however, and no information is available about the molecular mechanisms by which salt is pumped into bladder cells. This knowledge will allow breeders to utilise this, previously unexplored, trait to improve crop performance under conditions of salinity.Read moreRead less