Hybrid radiofrequency/optical catheter for effective atrial fibrillation ablation. This research project aims to advance engineering knowledge by applying an innovative, fibre-optics-based discrete optical coherence tomography to technology used for atrial fibrillation catheter ablation. RadioFrequency catheter-based ablation is far superior to cardiac drug therapy for atrial fibrillation patients. RadioFrequency catheters are not equipped with real-time lesion formation monitoring means, which ....Hybrid radiofrequency/optical catheter for effective atrial fibrillation ablation. This research project aims to advance engineering knowledge by applying an innovative, fibre-optics-based discrete optical coherence tomography to technology used for atrial fibrillation catheter ablation. RadioFrequency catheter-based ablation is far superior to cardiac drug therapy for atrial fibrillation patients. RadioFrequency catheters are not equipped with real-time lesion formation monitoring means, which enable the assessment of continuity-transmurality and prevent extra-cardiac complications, such as steam pops. Optical Coherece Tomography enables non-invasive, microscopic lesion formation assessment in real time during atrial fibrillation ablation procedures. The expected outcomes of this project are to develop a new hybrid fibre-optic/RadioFrequency catheter system and user-friendly driving software that will enable cardiac electrophysiologists to perform three key tasks not previously available.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100036
Funder
Australian Research Council
Funding Amount
$310,000.00
Summary
Super high speed grinding facility for difficult-to-machine materials and structures. This unique system will enable the manufacture of difficult-to-machine materials and structures with high quality and high productivity. It will support ground-breaking research activities across the country and help promote the strategic collaborations within Australian manufacturing society.
Discovery Early Career Researcher Award - Grant ID: DE150101005
Funder
Australian Research Council
Funding Amount
$378,288.00
Summary
Miniaturised fibre-optic probes for biomedical image and sensor data fusion. The project aims to develop new types of tiny biomedical imaging devices based on optical fibres that can be inserted into the body via hypodermic needles or catheters. These devices will have the ability to generate a three-dimensional image of the tissue region. As the devices will also be able to sense biochemical or mechanical properties of the tissue, they can be used to differentiate healthy from diseased tissue. ....Miniaturised fibre-optic probes for biomedical image and sensor data fusion. The project aims to develop new types of tiny biomedical imaging devices based on optical fibres that can be inserted into the body via hypodermic needles or catheters. These devices will have the ability to generate a three-dimensional image of the tissue region. As the devices will also be able to sense biochemical or mechanical properties of the tissue, they can be used to differentiate healthy from diseased tissue. These minimally invasive devices will produce information-rich multidimensional fused image and sensor data, opening up new possibilities for biologists and medical researchers to study disease progression and treatment in living animals and humans, with great potential for scientific discovery.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100184
Funder
Australian Research Council
Funding Amount
$183,437.00
Summary
Femtoliter Liquid Deposition Facility. This project aims to create a research capacity for direct printing of femtolitre volumes of functional liquids onto devices and surfaces. This project expects to enable the development of new sensing and electronic devices that require a novel fabrication step with delicate materials that cannot be deposited using existing processes. Expected outcomes include new chemical and biological sensors created through collaborative research between the partner in ....Femtoliter Liquid Deposition Facility. This project aims to create a research capacity for direct printing of femtolitre volumes of functional liquids onto devices and surfaces. This project expects to enable the development of new sensing and electronic devices that require a novel fabrication step with delicate materials that cannot be deposited using existing processes. Expected outcomes include new chemical and biological sensors created through collaborative research between the partner institutions and researchers. The benefits of this project should include the creation of a new rapid prototyping facility for Australian researchers, and the application of these capabilities for the development of new low-cost sensors for environmental gas sensing and glucose monitoring.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100035
Funder
Australian Research Council
Funding Amount
$4,743,710.00
Summary
ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to devel ....ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to develop ‘smart’ probes and ‘smart’ scanning, harnessing the digital revolution for better, cost effective diagnostic imaging and improved health outcomes.Read moreRead less
Robotic microsurgery: intra-operative measurement, modelling and micromanipulation control. This research will significantly improve microsurgery and minimally invasive surgery techniques, and further produce important benefits to medicine and healthcare. The project will also open new domains in the capabilities of modelling and control of complex systems with significant impact and benefits to numerous science and engineering practices.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100059
Funder
Australian Research Council
Funding Amount
$220,000.00
Summary
Multiplexed capabilities for surface analysis and imaging by mass spectrometry. This facility will support research aimed at developing rapid and reliable analytical methods for the detection of chemicals directly from biological and man-made materials. The mass spectroscopy methods used at the facility will reveal molecular-level changes in systems ranging from the lens of the human eye to Colorbond steel® and have applications in the detection of chemical and biological hazards.
Biomechanics Meets Robotics: Methods for Accurate and Fast Needle Targeting. This project intends to create a novel integrated framework for biomedical systems that can accurately target a needle. Accurate surgical targeting means less trauma and better patient outcomes. Needles are used in over half of all surgical procedures, but up to 38 per cent of these are affected by targeting errors. Achieving sub-millimetre accuracy is extremely difficult because inserting a needle displaces the tissue ....Biomechanics Meets Robotics: Methods for Accurate and Fast Needle Targeting. This project intends to create a novel integrated framework for biomedical systems that can accurately target a needle. Accurate surgical targeting means less trauma and better patient outcomes. Needles are used in over half of all surgical procedures, but up to 38 per cent of these are affected by targeting errors. Achieving sub-millimetre accuracy is extremely difficult because inserting a needle displaces the tissue and moves the target. How, then, can ultra-fine targeting be achieved? This project plans to integrate non-linear biomechanical models that predict tissue motion with accurate and principled motion control. It seeks to create new methods for surgical robots that will predict target motion and guide a needle to accurately intersect the target.Read moreRead less
A novel precision-engineered microfluidic chip for wear particle research. This project aims to develop 1- novel protocols to generate clinically-relevant wear particles from spinal implants in-vitro and 2- a technological framework for the fabrication of a novel microfluidic 3D spinal implant-on-a-chip with tailored mechanical, material and biological properties. This will provide a cost-effective tool, currently unavailable, that allows investigation into the impact of wear particles on health ....A novel precision-engineered microfluidic chip for wear particle research. This project aims to develop 1- novel protocols to generate clinically-relevant wear particles from spinal implants in-vitro and 2- a technological framework for the fabrication of a novel microfluidic 3D spinal implant-on-a-chip with tailored mechanical, material and biological properties. This will provide a cost-effective tool, currently unavailable, that allows investigation into the impact of wear particles on healthy spinal disc cells. We expect our technological framework to become an invaluable tool for biomedical engineers, biologists, and bio-engineers to work together and generate clinically relevant in-vitro data that supports optimisation for spinal implant design, fabrication, and safety. Read moreRead less