ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These resear ....ARC/NHMRC Research Network Fluorescence Applications in Biotechnology and Life Sciences. This Network will concentrate Australian research in new applications of fluorescence to biological systems to solve significant problems in health diagnostics, biotechnology and the environment. The scientific goals identified by the Network such as highly selective fluorescent labelling and purpose-engineered fluorochromes will be accompanied by the development of specialised instrumentation. These research directions pursued by strong multi-disciplinary teams spanning biology, chemistry, physics, bioengineering and medicine will benefit from the support of the Network programs. Through its focus on academic - industry collaboration the Network will also facilitate development of basic scientific discoveries into commercial outcomes.Read moreRead less
Imaging of properties of coherent elastic light scattering from turbid biological media. Imaging with coherent, elastically-scattered light for visualisation of thick-tissue morphology in vivo, or of cells buried deep in a turbid medium, remains a major challenge. We adopt an alternative approach of imaging of properties of light scattering based on regarding cellular tissue as a spatially-varying refractive-index continuum which encodes scattered light. We propose new methodologies to infer t ....Imaging of properties of coherent elastic light scattering from turbid biological media. Imaging with coherent, elastically-scattered light for visualisation of thick-tissue morphology in vivo, or of cells buried deep in a turbid medium, remains a major challenge. We adopt an alternative approach of imaging of properties of light scattering based on regarding cellular tissue as a spatially-varying refractive-index continuum which encodes scattered light. We propose new methodologies to infer tissue state and morphology indirectly based on phase delay, speckle, and angle-resolved scattering. We will break new ground in correlating the structure and function of in situ epithelial tissue and cells to light scattering enabling, e.g., the detection of mitosis and apoptosis in cells buried in thick, turbid media, and of cancers and precancers in vivo.Read moreRead less
Advances in optical coherence tomography. We propose to continue our research into the biomedical imaging technique of optical coherence tomography by making substantial new advances in the key areas of ultra-broad bandwidth operation, coincident confocal gate scanning, and dispersion compensation. These advances are aimed at improving resolution to the 1-5 micron range, which should allow a breakthrough to sub-cellular in vivo imaging, making visible sample histology in situ, which is currentl ....Advances in optical coherence tomography. We propose to continue our research into the biomedical imaging technique of optical coherence tomography by making substantial new advances in the key areas of ultra-broad bandwidth operation, coincident confocal gate scanning, and dispersion compensation. These advances are aimed at improving resolution to the 1-5 micron range, which should allow a breakthrough to sub-cellular in vivo imaging, making visible sample histology in situ, which is currently not possible. We also plan to make advances in the key area of scanning delay line technology by employing acousto-optics in OCT for the first time. Acousto-optics conveys advantages in no-moving-parts, scan-speed and accuracy.Read moreRead less
Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will signific ....Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will significantly benefit the mineral exploration industry as well as underwater detection of cables and ship wrecks.Read moreRead less
Advanced Electromagnetic Sensors and Magnetic Gradiometers for Natural Resources Exploration and Future Space Missions. Australia will benefit from the long-standing world-class mining exploration industry. The new magnetic gradiometer system would greatly enhance their arsenal of geophysical exploration tools, especially for the detection of both magnetically and/or conductive minerals like nickel sulphide. Due to the inherent skin depth issues of conductive cover, a unique condition in Austral ....Advanced Electromagnetic Sensors and Magnetic Gradiometers for Natural Resources Exploration and Future Space Missions. Australia will benefit from the long-standing world-class mining exploration industry. The new magnetic gradiometer system would greatly enhance their arsenal of geophysical exploration tools, especially for the detection of both magnetically and/or conductive minerals like nickel sulphide. Due to the inherent skin depth issues of conductive cover, a unique condition in Australia, a low frequency electromagnetic survey system is one of the best methods to penetrate the cover and investigate deeper geological structures. The low frequency isolation system developed in this project will improve the survey instrument performance down to 4Hz, providing capability to explore resources about 50-100% deeper than existing instrumentation allows.Read moreRead less
Experiments with Advanced Isolation Systems, Suspension and Test Masses Using ACIGA's High Optical Power Test Facility. This proposal will allow experimental verification of the performcane of of sapphire test masses and their associated isolation and suspension system in ACIGA's high optical power test facility at Gingin. The work will contribute to the worldwide effort to increase the sensitivity of laser interferometers to the level where known sources of gravitational waves can be detected ....Experiments with Advanced Isolation Systems, Suspension and Test Masses Using ACIGA's High Optical Power Test Facility. This proposal will allow experimental verification of the performcane of of sapphire test masses and their associated isolation and suspension system in ACIGA's high optical power test facility at Gingin. The work will contribute to the worldwide effort to increase the sensitivity of laser interferometers to the level where known sources of gravitational waves can be detected at a reasonable rate.Read moreRead less
Novel High-Q Resonant Structures for Space and Telecommunications. High-Q microwave resonators with low spurious mode density have important applications in telecommunications, radar, navigation, precision metrology and time standards. We will develop high-Q resonators by constructing a dielectric Bragg resonators using monocrystalline sapphire loaded in a copper cavity with new cylindrical and spherical geometries. Based on these devices, compact and economical state-of-the-art ultra-low noise ....Novel High-Q Resonant Structures for Space and Telecommunications. High-Q microwave resonators with low spurious mode density have important applications in telecommunications, radar, navigation, precision metrology and time standards. We will develop high-Q resonators by constructing a dielectric Bragg resonators using monocrystalline sapphire loaded in a copper cavity with new cylindrical and spherical geometries. Based on these devices, compact and economical state-of-the-art ultra-low noise microwave oscillators and hydrogen masers will be built for the telecommunications market and space applications.Read moreRead less
High Performance Microwave Oscillators for Radars, Comminication Systems and Precision Noise Measurements. The aim of the project is to develop a new class of microwave oscillators with unique combination of properties including low-noise, high frequency stability and reduced sensitivity to vibration. Such oscillators are essential for expanding fields of radar, fiber optics, optical frequency synthesis and metrology.
The industrial partner's focus will be on demands for reduced cost and impro ....High Performance Microwave Oscillators for Radars, Comminication Systems and Precision Noise Measurements. The aim of the project is to develop a new class of microwave oscillators with unique combination of properties including low-noise, high frequency stability and reduced sensitivity to vibration. Such oscillators are essential for expanding fields of radar, fiber optics, optical frequency synthesis and metrology.
The industrial partner's focus will be on demands for reduced cost and improved environmental performance, the university team will focus on improved frequency stability, optimal tuning and novel vibration immunity techniques.
Achieving the project goals will broaden the international markets for the industry partner's products and lead to increased export income for Australia.
Read moreRead less
Development of Optical Clocks and Their Applications to Precision Frequency Measurements and Time Keeping. The goal of the proposed international researcher exchange program is to enhance the ongoing collaboration between the Frequency Standards and Metrology (FSM) Group at the University of Western Australia and leading US research institutions, including National Institute of Standards and Technology (NIST) in the field of (i) laser cooled atomic frequency standards, (ii) methods of optical ....Development of Optical Clocks and Their Applications to Precision Frequency Measurements and Time Keeping. The goal of the proposed international researcher exchange program is to enhance the ongoing collaboration between the Frequency Standards and Metrology (FSM) Group at the University of Western Australia and leading US research institutions, including National Institute of Standards and Technology (NIST) in the field of (i) laser cooled atomic frequency standards, (ii) methods of optical frequency synthesis and coherent time transfer between widely separated parts of electromagnetic spectrum and (iii) generation of low noise microwave signals directly from frequency stabilised ultra-fast pulsed lasers.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882792
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
High Power Laser, Test Masses, Digital Control System and Vacuum System for High Optical Power Interferometry Experiments. Gravitational waves are expected to offer humanity a completely new spectrum with which to study the Universe. Australia has been a pioneer in the quest to open up this new spectrum. This project will allow Australia to play a key role in a world-wide project which aims for the first time to enable gravitational waves to be detected from black holes and neutron stars through ....High Power Laser, Test Masses, Digital Control System and Vacuum System for High Optical Power Interferometry Experiments. Gravitational waves are expected to offer humanity a completely new spectrum with which to study the Universe. Australia has been a pioneer in the quest to open up this new spectrum. This project will allow Australia to play a key role in a world-wide project which aims for the first time to enable gravitational waves to be detected from black holes and neutron stars throughout the universe. It will give Australia access to developed technologies, and will be a major boost to physical science research and education.Read moreRead less