Using Good Measurement Principles To Examine Musculoskeletal Disease And Improve The Evaluation Of New Diagnostic Tests
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
This proposal will apply good measurement principles to 2 important but under-resourced areas: 1) To examine risk factors for musculoskeletal disease (particularly osteoarthritis or “wear and tear” arthritis) and to determine how changes in these risk factors in our community will affect the burden of disease, thus identifying new targets for disease prevention. 2) To improve our ability to evaluate how well new diagnostic tests function when introduced into our healthcare system.
Molecular Epidemiology Of Cancers Of The Pancreas And Skin.
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Pancreatic cancer is the 4th most common cause of cancer death in Australia. The causes of this disease are largely unknown. I am conducting research designed to understand genetic and environmental causes of pancreatic cancer. Skin cancer occurs more frequently than any other cancer in Australia. Sunlight is the most common cause but it is also possible that human papilloma viruses may play a role. If high risk types of this virus can be identified, new preventive strategies may be developed.
Harnessing The Power Of Genomics To Understand Disease
Funder
National Health and Medical Research Council
Funding Amount
$470,144.00
Summary
The last 10 years have seen a revolution in our ability to sequence DNA and related molecules. This technological advancement has the potential to transform our knowledge of the mechanisms of development and disease. In order to harness the power of this technology, advances in analysis strategies and methods are critical to extract the important insights into these massive data sets. My research will lead the way in several major areas of bioinformatics research.