Discovery Early Career Researcher Award - Grant ID: DE160100843
Funder
Australian Research Council
Funding Amount
$330,000.00
Summary
Regulating gene delivery with light. This project seeks to deliver the capacity to remotely deliver molecules into specific cells without the need for invasive or viral procedures. Individual genetic predisposition to disease forms a key part of personalised medicine that requires the accurate delivery of drugs or genes. This project aims to develop a new multimodality microscopy that can investigate and optimise light delivery of macromolecules into living cells at high specificity and across a ....Regulating gene delivery with light. This project seeks to deliver the capacity to remotely deliver molecules into specific cells without the need for invasive or viral procedures. Individual genetic predisposition to disease forms a key part of personalised medicine that requires the accurate delivery of drugs or genes. This project aims to develop a new multimodality microscopy that can investigate and optimise light delivery of macromolecules into living cells at high specificity and across a multitude of cells. The expected outcome of this project is a new form of in vivo molecular delivery system using light.Read moreRead less
Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology ....Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology. Expected outcomes of this project include the development of a highly trained workforce and continued international collaboration in the field of high-technology sensor systems. This contribution to the GMT will provide significant benefits—it will change the way we view the Universe.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101402
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Advanced laser micromachining with femtosecond vector beams. This project is aimed at developing a new method for ultra-precision laser micromachining and dissection of biological tissues using femtosecond vector beams. The capability of these unconventional laser beams to process different materials with unsurpassed precision and efficiency offers significant economic and clinical benefits.
A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This ....Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This project aims to build on recent discoveries of new stimuli to implement objective tests with which to study structure vision with the Partner Organisation. The project aims to also expand on realistic models of how Structure Vision may be computed by just a few coupled cortical pyramidal cells.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100004
Funder
Australian Research Council
Funding Amount
$502,453.00
Summary
Semiconductor laser for adaptive optics in astronomy and space awareness. This project aims to create a laser system for use as a laser guide star. Semiconductor laser technology is a cost effective, highly reliable and compact alternative to expensive, inefficient, bulky laser systems. This laser has wide scientific appeal for research with telescopes in astronomy, and for satellite tracking and mitigation of the threat of space debris. Producing a sodium laser guide star in Australia is expect ....Semiconductor laser for adaptive optics in astronomy and space awareness. This project aims to create a laser system for use as a laser guide star. Semiconductor laser technology is a cost effective, highly reliable and compact alternative to expensive, inefficient, bulky laser systems. This laser has wide scientific appeal for research with telescopes in astronomy, and for satellite tracking and mitigation of the threat of space debris. Producing a sodium laser guide star in Australia is expected to secure the country's position as the premier provider of commercial-grade laser guide star adaptive optics systems for civil and defence telescopes around the world.Read moreRead less
Illuminating the cosmic web with Fast Radio Bursts. This project aims to establish the use of millisecond-duration Fast Radio Bursts as a wholly new means to map out the distribution of matter in the Universe. This project expects to localise 100s of bursts using novel infrastructure deployed on Australia's largest radio telescopes. Expected outcomes include an understanding of the processes that shape both the large-scale structures of the Universe, and the extreme conditions that exist at the ....Illuminating the cosmic web with Fast Radio Bursts. This project aims to establish the use of millisecond-duration Fast Radio Bursts as a wholly new means to map out the distribution of matter in the Universe. This project expects to localise 100s of bursts using novel infrastructure deployed on Australia's largest radio telescopes. Expected outcomes include an understanding of the processes that shape both the large-scale structures of the Universe, and the extreme conditions that exist at the sites of Fast Radio Bursts. This should provide significant benefits to our fundamental knowledge of the Universe, inspire students into careers in science, technology, engineering and mathematics, and develop signal processing techniques of application to both the Square Kilometre Array and industry.Read moreRead less
High-cadence near-infrared imaging. This project aims to deploy a cryogenic camera system to improve the outputs of astronomical telescopes. The system is equipped with an emerging detector technology, a near-infrared Avalanche Photo-Diode array, capable of high cadence imaging with frame rates of 10 - 1,000 Hz at a wavelength of around 2.2 microns. This new technology is a key component to the future of adaptive optics systems for astronomical telescopes as it allows the rapid measurements nece ....High-cadence near-infrared imaging. This project aims to deploy a cryogenic camera system to improve the outputs of astronomical telescopes. The system is equipped with an emerging detector technology, a near-infrared Avalanche Photo-Diode array, capable of high cadence imaging with frame rates of 10 - 1,000 Hz at a wavelength of around 2.2 microns. This new technology is a key component to the future of adaptive optics systems for astronomical telescopes as it allows the rapid measurements necessary to correct the image blurring introduced by the Earth's atmosphere. No expertise currently exists in Australia with this new technology. Capitalising on previous investment, the camera system is intended to fill a capability gap in local expertise and to ensure the potential of the next generation of telescopes is realised and strengthen our competitive edge for frontier instrumentation across the wider Australian imaging community.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100002
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detect ....Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detectable by telescopes, the impact of gravitational wave detections on our understanding of the universe is inestimable. Australian partnership intends to enable our physicists and astronomers to be at the vanguard of this brand new field and inspire a new generation to study the physical sciences.Read moreRead less
X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect t ....X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect to develop software and hardware techniques to realise its potential and extend it to ghost tomography. The focus of this project is on reducing cancer risk in medical imaging, and allowing real-time quality control for 3D printing in safety-critical industries such as aerospace.Read moreRead less