Development of microwave tomography techniques and inverse methods for biomedical imaging applications. Microwave tomography is a rapidly emerging imaging technology with highly significant applications in industry and medicine. In particular, given its sensitivity to differences between normal and malignant breast tissue, non-invasive microwave imaging has been the subject of intense research interest in the last ten years. In collaboration with workers at Chalmers University in Sweden, we wi ....Development of microwave tomography techniques and inverse methods for biomedical imaging applications. Microwave tomography is a rapidly emerging imaging technology with highly significant applications in industry and medicine. In particular, given its sensitivity to differences between normal and malignant breast tissue, non-invasive microwave imaging has been the subject of intense research interest in the last ten years. In collaboration with workers at Chalmers University in Sweden, we will develop and evaluate a scanning microwave imaging tomographic system with a number of potential industrial and biomedical applications. This appears to be a new Australian initiative.Read moreRead less
Advanced Atomic Sources for Precision Measurement. Many advances in our technology-driven society rely on the precision measurement of quantities such as accelerations, magnetic and electric fields. A higher level of measurement precision leads to a clear economic or strategic advantage. We expect to provide the Australian industrial and government sectors with new and better methods for making precise measurements with accelerometers, gyroscopes and gravity gradiometers. This proposal will pla ....Advanced Atomic Sources for Precision Measurement. Many advances in our technology-driven society rely on the precision measurement of quantities such as accelerations, magnetic and electric fields. A higher level of measurement precision leads to a clear economic or strategic advantage. We expect to provide the Australian industrial and government sectors with new and better methods for making precise measurements with accelerometers, gyroscopes and gravity gradiometers. This proposal will place Australia with only a handful of other countries as an international leader in the new technology of coherent atom interferometry. It is expected that this proposal will lead to innovative prototype devices as well as significant patentable technology. Read moreRead less
3D Image segmentation and shape characterisation driven by topological persistence. Tomographic imaging is emerging as a new tool to help tackle a remarkable array of scientific challenges. What distinguishes healthy bone from that of osteoporosis sufferers? How does groundwater contamination spread? Why is a macadamia nut so hard to crack? What causes the iridescence in a butterfly wing? These are just a few of the questions being answered at tomographic facilities in Australia alone. By co ....3D Image segmentation and shape characterisation driven by topological persistence. Tomographic imaging is emerging as a new tool to help tackle a remarkable array of scientific challenges. What distinguishes healthy bone from that of osteoporosis sufferers? How does groundwater contamination spread? Why is a macadamia nut so hard to crack? What causes the iridescence in a butterfly wing? These are just a few of the questions being answered at tomographic facilities in Australia alone. By combining sophisticated mathematics with cutting edge image-processing algorithms, this project will yield a new class of topology driven image analysis techniques that will improve the accuracy and reliability of predictions made from tomographic images.Read moreRead less
Universal quantum imaging. This project will integrate quantum technology with the rapidly advancing techniques of spatial light modulation utilised in LCD displays and video projectors. We will develop, for the first time, broadly versatile imaging technology based on quantum mechanics, enabling both important applications in future medical diagnostic devices and communication systems; and fundamental advances in the biological and quantum sciences. Quantum technologies offer the promise to rev ....Universal quantum imaging. This project will integrate quantum technology with the rapidly advancing techniques of spatial light modulation utilised in LCD displays and video projectors. We will develop, for the first time, broadly versatile imaging technology based on quantum mechanics, enabling both important applications in future medical diagnostic devices and communication systems; and fundamental advances in the biological and quantum sciences. Quantum technologies offer the promise to revolutionise many aspects of modern life, from computing and communications, to medical imaging and metrology. This project will put Australia at the international forefront of quantum imaging, enhancing Australia's already significant international presence in the area.Read moreRead less
Cubesat Technologies for High Spatial Resolution Astrophysics. This project aims to combine cubesat and hybrid cubesat/micro-satellite concepts studied in Australia and Japan, prototyping and space-qualifying the most custom components, enabling a future affordable launch. High angular resolution is critical for studying processes of star formation, black holes, and exoplanets. An array of small satellites can greatly exceed the angular resolution of a single telescope, or the sensitivity of atm ....Cubesat Technologies for High Spatial Resolution Astrophysics. This project aims to combine cubesat and hybrid cubesat/micro-satellite concepts studied in Australia and Japan, prototyping and space-qualifying the most custom components, enabling a future affordable launch. High angular resolution is critical for studying processes of star formation, black holes, and exoplanets. An array of small satellites can greatly exceed the angular resolution of a single telescope, or the sensitivity of atmosphere-limited ground-based interferometers. Space qualifying the key inter-spacecraft metrology and fibre injection technologies will not only enable a future Australian satellite astrophysical interferometer, but is also relevant for optical communications links and earth observations. Read moreRead less
Quantum opto-mechanics with whispering gallery modes in crystalline materials. Deep understanding and fine control of quantum phenomena will be increasingly important in 21st century technology. This Discovery Project aims to develop cutting edge expertise in ultra-precision machining for the realization of crystalline ring resonators that have very high optical and mechanical Q-factors. These structures will enable novel experiments in non-linear optics, quantum state generation, precision met ....Quantum opto-mechanics with whispering gallery modes in crystalline materials. Deep understanding and fine control of quantum phenomena will be increasingly important in 21st century technology. This Discovery Project aims to develop cutting edge expertise in ultra-precision machining for the realization of crystalline ring resonators that have very high optical and mechanical Q-factors. These structures will enable novel experiments in non-linear optics, quantum state generation, precision metrology and quantum opto-mechanical coupling. Results of our investigations will lead to compact devices for quantum information technologies, new geometries for single atom detection, and a deeper understanding of meso-scale quantum mechanical systems.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Understanding the deep mantle: experimental petrology at very high pressures. The great processes that shape the Earth at its surface, including plate tectonics and continental drift, can only be understood by appreciating how the interior of the Earth works. However, studying the deep Earth is difficult because of the enormous pressures and temperatures involved. This research proposes to simulate conditions in the Earth's lower mantle (that is, below 670 km in depth) by making use of an Austra ....Understanding the deep mantle: experimental petrology at very high pressures. The great processes that shape the Earth at its surface, including plate tectonics and continental drift, can only be understood by appreciating how the interior of the Earth works. However, studying the deep Earth is difficult because of the enormous pressures and temperatures involved. This research proposes to simulate conditions in the Earth's lower mantle (that is, below 670 km in depth) by making use of an Australian invented diamond-based ceramic, to double the pressure at which experiments can be performed. The information gained from this fundamental research will help predict how giant ore bodies form. The development of the high-pressure apparatus will also aid material scientists in their quest for novel materials.Read moreRead less
THE FIRST DEVELOPMENT OF MULTI-DIMENSIONAL SPECTRO-ELECTROCHEMISTRY AND ITS APPLICATION TO CRUCIAL TRANSFORMATIONS IN INORGANIC SYSTEMS. Electrolysis is a very widespread and efficient method of chemical synthesis both in industry and research. However, the link between the control voltage and the resultant current is often complicated and easily misinterpreted. To overcome this fundamental problem, we propose an optical spectro-electrochemistry instrument based on a two-dimensional CCD detectio ....THE FIRST DEVELOPMENT OF MULTI-DIMENSIONAL SPECTRO-ELECTROCHEMISTRY AND ITS APPLICATION TO CRUCIAL TRANSFORMATIONS IN INORGANIC SYSTEMS. Electrolysis is a very widespread and efficient method of chemical synthesis both in industry and research. However, the link between the control voltage and the resultant current is often complicated and easily misinterpreted. To overcome this fundamental problem, we propose an optical spectro-electrochemistry instrument based on a two-dimensional CCD detection array. This radically new approach enables simultaneous spectroscopic and spatial data mapping in the realm adjacent to an electrode surface. Important applications range from unequivocal identification of elusive molecules to monitoring metal corrosion. Our first objective is to elucidate certain crucial transformations of mono- and binuclear heavy metal complexes.Read moreRead less
Gravitational wave detection through millisecond pulsar timing. This project aims to detect gravitational waves (GWs) using precision pulsar timing observations. Direct detection of GWs is of huge international importance and would place Australia at the forefront of the new research field of GW astronomy. The project provides a link between current GW detection experiments and the GW astronomy that will become commonplace with future telescopes such as the Square Kilometre Array (SKA). It wil ....Gravitational wave detection through millisecond pulsar timing. This project aims to detect gravitational waves (GWs) using precision pulsar timing observations. Direct detection of GWs is of huge international importance and would place Australia at the forefront of the new research field of GW astronomy. The project provides a link between current GW detection experiments and the GW astronomy that will become commonplace with future telescopes such as the Square Kilometre Array (SKA). It will answer important questions in relativistic astrophysics, cosmology and planetary astronomy. The groundwork for SKA science proposed here will demonstrate Australian commitment to the SKA. Read moreRead less