Evidence Innovation: Transforming The Efficiency Of Systematic Review
Funder
National Health and Medical Research Council
Funding Amount
$928,417.00
Summary
Australia invests considerable resources developing reliable summaries of research evidence to understand the benefits and risks of drugs and health programs. We will use information technologies and ‘crowdsourcing’ to improve the production of evidence summaries, evaluate this approach in a randomised study, and facilitate implementation throughout Australia. This will improve the translation of research into health practice and policy, reducing research waste and improving health outcomes.
Changing Decision-making Behaviour In General Practice By Providing Access To Online Evidence.
Funder
National Health and Medical Research Council
Funding Amount
$206,375.00
Summary
The case for a shift to evidence-based practice, and the substantial economic and health outcome benefits of that shift, have been repeatedly made. Despite the vision, significant barriers to evidence-based practice remain, and the demonstration of a positive role for on-line systems would result in a significant change in strategies for clinician behaviour change. This study will make a specific and significant contribution to our understanding of the efficacy and effectiveness of online eviden ....The case for a shift to evidence-based practice, and the substantial economic and health outcome benefits of that shift, have been repeatedly made. Despite the vision, significant barriers to evidence-based practice remain, and the demonstration of a positive role for on-line systems would result in a significant change in strategies for clinician behaviour change. This study will make a specific and significant contribution to our understanding of the efficacy and effectiveness of online evidence retrieval systems as a component in any evidence-based strategy, through a rigorous and controlled approach to the study of clinical behaviour change. It will also provide a powerful test of the value of search filters as a specific technology in support of evidence retrieval. The focus on prescribing patterns in NHMRC priority areas as an outcome measure will also provide a significant data set reflecting current practice in primary care.Read moreRead less
Personally Controlled Electronic Health Records For Young Adults With Communication Disabilities: Charting The Course For Successful Child To Adult Health Service Transition.
Funder
National Health and Medical Research Council
Funding Amount
$400,665.00
Summary
Adolescents and young adults with chronic health conditions and communication disabilities struggle to communicate their health information with service providers. This causes problems in care when moving from child to adult health services. This study will investigate their use of the Personally Controlled Electronic Health Record as a means to support timely and effective information exchange to improve healthcare for these vulnerable young adults.
Monitoring The Gap Between Evidence And Vaccination Behaviour By Sampling The Location-specific Consumption Of Health Information From News And Social Media
Funder
National Health and Medical Research Council
Funding Amount
$476,648.00
Summary
Vaccination programs have saved millions of lives in the last decade but vaccine refusal threatens their success. We propose new methods for tracking social media to measure how people in different locations are exposed to different information about vaccines from the media and other sources. This will help us understand why some communities appear to be more susceptible to vaccine hesitancy, and help public health organisations more effectively address the problem of vaccine acceptance.
Using Next-generation Sequencing Technology To Identify Genetic Determinants Of Epilepsy And Sporadic Epilepsy Prognosis
Funder
National Health and Medical Research Council
Funding Amount
$322,282.00
Summary
Recent advances in high-throughput, next-generation, DNA sequencing allows biologists to simultaneously analyse the differences in thousands of different genes across affected and unaffected individuals. However, it produces an overwhelming amount of data and making sense of this deluge of data is a current challenge. Overcoming this challenge will enable scientific discoveries of pathogenic variants of disease, potentially providing an opportunity for targeted drug development.
We will conduct a clinical trial of the effectiveness of a continuous auditory display of an anesthetized patient's respiratory status. Expired carbon dioxide monitoring has helped reduce respiratory incidents since its widespread introduction in the late 1980s, but a continuous auditory display of respiratory status may reduce incidents further. We will conduct a clinical trial with 10 anaesthetists of continuous auditory respiratory monitoring. Successful outcome may lead to commercial uptake.
Using Collaboration Networks To Measure Bias And Inefficiency In The Production And Translation Of Evidence About Cardiovascular Risk
Funder
National Health and Medical Research Council
Funding Amount
$219,806.00
Summary
Doctors rely on clinical trials comparing the safety and efficacy of cardiovascular treatments but are often unable to find or trust the information they seek because of problems in evidence translation. This project will examine the networks of collaboration amongst researchers and their research to identify the source of these problems. The research will be used to identify where to intervene in the process, in turn helping doctors to make safe and cost-effective decisions for their patients.
Systems For Control And Tracking Of Infectious Diseases In A Globalised World
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
Infectious disease informatics now at the forefront of translational research due to the recent rapid growth of microbial genomics, significant advances in molecular diagnostics and increasing demands for real-time biosurveillance. This program of multidisciplinary research will redefine existing paradigms, develop novel systems for surveillance of biothreats and offer new insights into transmission dynamics of pathogens with epidemic potential in Australia.