Early Career Industry Fellowships - Grant ID: IE230100098
Funder
Australian Research Council
Funding Amount
$417,000.00
Summary
Hunting high and low: mapping ancient topography to find copper. Transitioning to a decarbonised society requires significant amounts of copper; however, preventing a systems-based exploration approach for copper is the lack of a first-order dataset of the Earth’s surface evolution, known as palaeogeography. This project aims to unearth potential areas of porphyry copper through deep time by developing innovative global palaeogeography reconstructions. Expected outcomes of this project include n ....Hunting high and low: mapping ancient topography to find copper. Transitioning to a decarbonised society requires significant amounts of copper; however, preventing a systems-based exploration approach for copper is the lack of a first-order dataset of the Earth’s surface evolution, known as palaeogeography. This project aims to unearth potential areas of porphyry copper through deep time by developing innovative global palaeogeography reconstructions. Expected outcomes of this project include new quantitative palaeogeography reconstructions, as well as the first well-constrained reconstructions of copper preservation potential. This should provide benefits such as an improved understanding of the porphyry copper lifecycle, with significant impacts for resource exploration and decarbonisation efforts.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100118
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracki ....The National Cycling Data and Analysis Platform (NCDAP) . A National Cycling Data and Analytics Platform to collect, integrate and communicate new and historic data on cycling infrastructure, attitudes, and behaviours. This project will address the significant issue of data fragmentation, pilot a national cycling survey, and develop a cycling toolkit to allow exploring and testing various cycling infrastructure scenarios. The platform will provide an open access e-Infrastructure to enable tracking social and cultural changes that influence transport choices, create effective behaviour change programs and prioritise cycling infrastructure investment. This project will contribute to healthier lifestyles, reduced traffic congestion and emissions and energy efficiency of Australia’s transport sector.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101137
Funder
Australian Research Council
Funding Amount
$458,665.00
Summary
Exploiting biological noise for next generation electrochemical biosensors. This project aims to harness the intrinsic noise in a biological system to develop a new platform for biosensors. This will lead to advancement of a new versatile electrochemical platform for real-time screening with vast applications that span from sensing at sub-cellular level to point-of-care and implantable biosensors. The new sensory technique will improve the specificity, sensitivity and resolution in biosensors an ....Exploiting biological noise for next generation electrochemical biosensors. This project aims to harness the intrinsic noise in a biological system to develop a new platform for biosensors. This will lead to advancement of a new versatile electrochemical platform for real-time screening with vast applications that span from sensing at sub-cellular level to point-of-care and implantable biosensors. The new sensory technique will improve the specificity, sensitivity and resolution in biosensors and enables measurement of multiple biomarkers simultaneously in real-time. The outcomes will contribute to a better understanding of fundamental physiological processes and chemical interactions at subcellular level which will inform future advancements in biomedical engineering.
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The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyami ....The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyamines, as we have discovered that polyamines are regulated by iron at 2-major levels, involving >10-key polyamine pathway proteins. This proposal represents first-in-field studies specifically designed to dissect mechanisms involved in this relationship. Our Central Hypothesis is that iron regulates polyamine metabolism.Read moreRead less
A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce ....A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce a platform technology designed for subscalp anatomy with future use in various brain-machine interfacing applications relying on reliable, long-term and easy-to-implant systems. This project's device manufacturing, training, and intellectual property are expected to strengthen Australia's position in bioelectronics.Read moreRead less
Communicating to promote engagement in using electronic medical records. This reflexive ethnographic and co-design project aims to examine how patient and family participation occurs with health professionals in using the electronic medical record within hospitals, especially for patients with complex needs. Its significance involves working with patients and families to consider how they could take part in decision making activities across transitions of care and influence health care activitie ....Communicating to promote engagement in using electronic medical records. This reflexive ethnographic and co-design project aims to examine how patient and family participation occurs with health professionals in using the electronic medical record within hospitals, especially for patients with complex needs. Its significance involves working with patients and families to consider how they could take part in decision making activities across transitions of care and influence health care activities. Outcomes are new knowledge and practices about how communication occurs with the electronic medical record and strategies adopted for effective engagement. Benefits are increased understanding of how and under what circumstances, engagement can take place in using the electronic medical record.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100035
Funder
Australian Research Council
Funding Amount
$4,743,710.00
Summary
ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to devel ....ARC Training Centre for Innovation in Biomedical Imaging Technology. The ARC Training Centre for Innovation in Biomedical Imaging Technology expects to train 20 industry-ready innovation scientists who will undertake industry-driven research in the development and application of novel diagnostics, therapeutics and theranostics. They will inform changes in regulatory policy that support industry growth. The Centre will build multidisciplinary links between researchers and within industry to develop ‘smart’ probes and ‘smart’ scanning, harnessing the digital revolution for better, cost effective diagnostic imaging and improved health outcomes.Read moreRead less
A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using ....A miniaturised laser manipulator for ultra-precise and pain-free dentistry. This project aims to develop a miniaturized high-precision laser robotic device that can fit comfortably in the mouth to perform pain-free, vibration-free dental operations by utilising silicon-carbide on silicon technology to create a millimetre-sized two-axis controllable, highly-reflective mirror robust to high-power ultra-short laser pulses. This project expects to generate new knowledge in micro-mirror control using optically excited piezo-resistive sensors, and cold femtosecond laser ablation of hard dental tissue. Expected outcomes include a working prototype for laser removal of tooth materials at speeds exceeding dental drills, providing benefits in miniaturized laser devices and ultimately removing pain from dental procedures. Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC160100027
Funder
Australian Research Council
Funding Amount
$4,340,802.00
Summary
ARC Training Centre for Biopharmaceutical Innovation. ARC Training Centre for Biopharmaceutical Innovation. This centre aims to transform Australia’s growing biopharmaceutical industry, an advanced manufacturing capability, by training specialist biotechnologists and bioengineers. It expects the research and development outputs will create new biopharmaceuticals and antibody-based reagents, enhanced production methods, improved manufacturing capabilities and a cohort of specialist scientists. Ne ....ARC Training Centre for Biopharmaceutical Innovation. ARC Training Centre for Biopharmaceutical Innovation. This centre aims to transform Australia’s growing biopharmaceutical industry, an advanced manufacturing capability, by training specialist biotechnologists and bioengineers. It expects the research and development outputs will create new biopharmaceuticals and antibody-based reagents, enhanced production methods, improved manufacturing capabilities and a cohort of specialist scientists. New biopharmaceuticals are expected to benefit the Australian economy and provide new therapeutic options for better health outcomes. Industry-driven research projects will also provide industry-ready graduates who can drive future growth in the sector.Read moreRead less