Real-time neuronal network imaging using diamond optrode arrays. The project aims to develop new imaging technology for real time recording of electrical activity from cell and neuronal networks with unprecedented resolution and scale. The technology innovation stems from an optical defect in diamond which can be engineered to sensitively detect local changes in electric field. The all-optical diamond optrode array devices will be applied to biological model systems including cardiomyocytes, mam ....Real-time neuronal network imaging using diamond optrode arrays. The project aims to develop new imaging technology for real time recording of electrical activity from cell and neuronal networks with unprecedented resolution and scale. The technology innovation stems from an optical defect in diamond which can be engineered to sensitively detect local changes in electric field. The all-optical diamond optrode array devices will be applied to biological model systems including cardiomyocytes, mammalian cells, and neurons; and will be benchmarked against current state-of-the-art technologies. The knowledge gained from the high density recordings will aid predictive models of disease and will lead to an improved understanding of the brain’s micro circuity and functional connectome.Read moreRead less
Imaging the invisible. This project aims to develop imaging technology to see and quantify objects normally invisible with X-rays. It will develop an X-ray imaging system that should provide orders of magnitude greater sensitivity to subtle changes in material composition than conventional radiography. It will devise quantitative image analysis tools for isolating specific materials of interest from complex multi-material samples, including low density components that often go undetected. Indust ....Imaging the invisible. This project aims to develop imaging technology to see and quantify objects normally invisible with X-rays. It will develop an X-ray imaging system that should provide orders of magnitude greater sensitivity to subtle changes in material composition than conventional radiography. It will devise quantitative image analysis tools for isolating specific materials of interest from complex multi-material samples, including low density components that often go undetected. Industries that could benefit significantly from this technology include airport security, the mining sector, agriculture, manufacturing quality control, and biomedical researchers studying anatomical form and function.Read moreRead less
Non-destructing X-ray testing. This project aims to improve imaging with X-rays, providing better image quality with higher throughput at a lower radiation dose. It will develop an X-ray imaging system that provides orders of magnitude greater sensitivity for detecting low-density objects that are often invisible with conventional X-ray scanners, and quantitative image analysis tools that can isolate materials from complex multi-material samples and detect individual chemical elements. Significa ....Non-destructing X-ray testing. This project aims to improve imaging with X-rays, providing better image quality with higher throughput at a lower radiation dose. It will develop an X-ray imaging system that provides orders of magnitude greater sensitivity for detecting low-density objects that are often invisible with conventional X-ray scanners, and quantitative image analysis tools that can isolate materials from complex multi-material samples and detect individual chemical elements. Significant benefits from these technologies are expected in industries including airport security, mining, agriculture, manufacturing quality control, and in research fields from medicine to geology.Read moreRead less
Dynamic multi-modal x-ray imaging. This project aims to create sensitive new methods of x-ray imaging that capture multiple image modalities with a single snapshot. Conventional x-ray imaging is widely used in a range of industries, but captures only a fraction of the rich information that is available in the x-ray wavefield. This project expects to extract additional image modalities to reveal x-ray-transparent features, and detect microscopic textures. By combining these capabilities with the ....Dynamic multi-modal x-ray imaging. This project aims to create sensitive new methods of x-ray imaging that capture multiple image modalities with a single snapshot. Conventional x-ray imaging is widely used in a range of industries, but captures only a fraction of the rich information that is available in the x-ray wavefield. This project expects to extract additional image modalities to reveal x-ray-transparent features, and detect microscopic textures. By combining these capabilities with the ability to capture images of a moving sample, this project will enable innovative biomedical and materials research studies, and develop new imaging technologies for use in security, hospitals and manufacturing. New methods of x-ray imaging will have wide-ranging benefits for society, the economy and healthcare.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775729
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Improved understanding of nanoscale materials - structure, composition, crystallography and defects revealed by electron imaging and analysis at high spatial resolution. Modern materials scientists and engineers are driven by world-wide competition to develop new technology and manufactured devices. The trend has for some time been towards miniaturisation and one of the main challenges lies in effectively characterising nanostructures that are produced as a key step in research and development o ....Improved understanding of nanoscale materials - structure, composition, crystallography and defects revealed by electron imaging and analysis at high spatial resolution. Modern materials scientists and engineers are driven by world-wide competition to develop new technology and manufactured devices. The trend has for some time been towards miniaturisation and one of the main challenges lies in effectively characterising nanostructures that are produced as a key step in research and development of advanced materials. The proposed electron microscope and detectors will provide a state-of-the-art analytical facility to support the cross-disciplinary materials science and nanotechnology research at the Australian National University. It will also provide an important training facility for students and early-career researchers and will be available to investigators from other Australian institutions.Read moreRead less
Optical Fibre Touch Sensor for Cochlear Implants. The touch sensor will be part of a cochlear implant, which is surgically implanted to provide a sense of hearing for people who are profoundly or severely deaf. Approximately 100,000 people worldwide have received cochlear implants so far. However, the delicate internal structures of the ear can easily be damaged when the implant is inserted. By helping surgeons to preserve the inner ear, this sensor will help to further improve the hearing abili ....Optical Fibre Touch Sensor for Cochlear Implants. The touch sensor will be part of a cochlear implant, which is surgically implanted to provide a sense of hearing for people who are profoundly or severely deaf. Approximately 100,000 people worldwide have received cochlear implants so far. However, the delicate internal structures of the ear can easily be damaged when the implant is inserted. By helping surgeons to preserve the inner ear, this sensor will help to further improve the hearing ability of future patients. The 'bionic ear' was invented in Australia and this project will help to ensure the continued success of Australia's world leading implant industry.Read moreRead less
Silicon Photonic Platform for Quantum Encryption and Communications. The integrity of a secure communications link can mean the difference between life and death in a defence environment. In the civilian arena, the security of electronic financial transactions is also critical to guard against 'cyber' theft. Encryption of data using unique quantum 'noise' as a key has been proposed as an exceptionally strong approach. Attempts to intercept the key during transmission can easily be detected.
....Silicon Photonic Platform for Quantum Encryption and Communications. The integrity of a secure communications link can mean the difference between life and death in a defence environment. In the civilian arena, the security of electronic financial transactions is also critical to guard against 'cyber' theft. Encryption of data using unique quantum 'noise' as a key has been proposed as an exceptionally strong approach. Attempts to intercept the key during transmission can easily be detected.
Quantum key transmission has been demonstrated but requires impractically expensive, bulky and exotic equipment. This project will explore low-cost, silicon chip based quantum key transfer modules. Our aim is to render quantum encryption as simple as adding an expansion card to a standard computer or portable device.Read moreRead less
New quantitative methods in X-ray imaging using crystal optics. This project will enhance Australian science's international leadership in the area of x-ray imaging. This powerful type of X-ray imaging, which makes use of optical elements made of perfect crystals, is specially tailored to image samples which are invisible to conventional x-ray techniques. Such "extended x-ray vision" is extremely important for imaging in medicine, biology and materials science. Furthermore, we will train x-ray s ....New quantitative methods in X-ray imaging using crystal optics. This project will enhance Australian science's international leadership in the area of x-ray imaging. This powerful type of X-ray imaging, which makes use of optical elements made of perfect crystals, is specially tailored to image samples which are invisible to conventional x-ray techniques. Such "extended x-ray vision" is extremely important for imaging in medicine, biology and materials science. Furthermore, we will train x-ray scientists of tomorrow, whose expertise will allow Australia to capitalize on its investment in the Australian Synchrotron.Read moreRead less
High-brightness wavelength tuneable lasers for quantum science. This project aims to establish the capability to manufacture application-specific semiconductor lasers. The project will use existing facilities in Australia to enhance our world-leading quantum science research, and establish a viable export-dominated high-tech manufacturing business. Semiconductor lasers are a critical enabling technology for many scientific applications, particularly for quantum science including quantum computin ....High-brightness wavelength tuneable lasers for quantum science. This project aims to establish the capability to manufacture application-specific semiconductor lasers. The project will use existing facilities in Australia to enhance our world-leading quantum science research, and establish a viable export-dominated high-tech manufacturing business. Semiconductor lasers are a critical enabling technology for many scientific applications, particularly for quantum science including quantum computing and quantum sensing. This project is expected to enable the establishment of a high-tech manufacturing capability to support Australia's leading role in quantum science, and expand our scientific instrumentation exports to new and rapidly developing applications such as magnetic sensing and imaging at nanoscale, quantum communication and computation.Read moreRead less
Multiphoton microscopy through tissue turbid media. The aim of this proposal is to conduct the collaborative project on multi-photon microscopic imaging through biological tissue, which has been recently initiated between Swinburne University of Technology (SUT) and Massachusetts Institute of Technology (MIT). It will integrate the special skills, two-photon fluorescence endoscopy and second-harmonic coherence tomography, investigated in the respective collaborating institutes, to develop a nove ....Multiphoton microscopy through tissue turbid media. The aim of this proposal is to conduct the collaborative project on multi-photon microscopic imaging through biological tissue, which has been recently initiated between Swinburne University of Technology (SUT) and Massachusetts Institute of Technology (MIT). It will integrate the special skills, two-photon fluorescence endoscopy and second-harmonic coherence tomography, investigated in the respective collaborating institutes, to develop a novel method for detecting/imaging cancer cells that are located at 1 mm below tissue surfaces, while they are still in the early stage to be cured. Consequently, a diagnostic method for early cancer detection particularly through skin tissue becomes possible.Read moreRead less