Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668471
Funder
Australian Research Council
Funding Amount
$262,706.00
Summary
Hyphenated Capillary Electrophoresis - Mass Spectrometry Facility. The requested funding will facilitate the expansion of the activities of the University of Tasmania (UTas) node of the Australian Centre for Research on Separation Science and its collaborators. This initiative will involve the application of integrated, high resolution technologies for the separation and identification of complex chemical and biological samples. The instrument is to be shared by a number of highly research-activ ....Hyphenated Capillary Electrophoresis - Mass Spectrometry Facility. The requested funding will facilitate the expansion of the activities of the University of Tasmania (UTas) node of the Australian Centre for Research on Separation Science and its collaborators. This initiative will involve the application of integrated, high resolution technologies for the separation and identification of complex chemical and biological samples. The instrument is to be shared by a number of highly research-active groups at UTas in the fields of chemistry, biochemistry, plant and agricultural science, Antarctic studies, and pharmacy where detailed structural identification of components separated from complex mixtures is essential. These projects all focus on fundamental and applied research of great national significance.Read moreRead less
Skin friction control using engineering and biological surface coatings. The development of techniques to reduce skin friction in water conveying assets will increase renewable energy production from existing hydro-electric plant and improve the energy efficiency of water conveying utilities. There is also potential for application to marine biofouling problems and reducing fuel usage by shipping. Passive (non-chemical) and biological control methods to reduce fouling and friction will be sought ....Skin friction control using engineering and biological surface coatings. The development of techniques to reduce skin friction in water conveying assets will increase renewable energy production from existing hydro-electric plant and improve the energy efficiency of water conveying utilities. There is also potential for application to marine biofouling problems and reducing fuel usage by shipping. Passive (non-chemical) and biological control methods to reduce fouling and friction will be sought to minimise environmental impact and maintain potable water quality. This multidisciplinary project combining engineering, photogrammetry and biological sciences will provide valuable training for the project team members and develop a pool of skilled personnel available to Australian industries.Read moreRead less
Improvement of water conveying efficiency in hydroelectric power generation systems by optimising pipe friction losses. The growth of bacterial and algal slimes on the surface of water conveying system significantly reduces the net electricity generation from Tasmania's hydroelectric system.
The aim of this project is to develop an optimal maintenance strategy to control this growth which will balance maintenance downtime against the potential increase in electricity production. The growth resp ....Improvement of water conveying efficiency in hydroelectric power generation systems by optimising pipe friction losses. The growth of bacterial and algal slimes on the surface of water conveying system significantly reduces the net electricity generation from Tasmania's hydroelectric system.
The aim of this project is to develop an optimal maintenance strategy to control this growth which will balance maintenance downtime against the potential increase in electricity production. The growth response to cleaning techniques and surface coatings will be investigated.
The potential for increased power production from this renewable energy source will have considerable economic benefit for Tasmania.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvasc ....Blood flow routes in muscle. Ageing well, ageing productively. The Australian population is ageing. The proportion of the population over the age of 65 is expected to greatly increase, reaching 22% by the year 2030. The prevalence of type 2 diabetes in this older population is thought to be ~20%, compared to ~6% in younger populations. An initial cause of type 2 diabetes may be microvascular dysfunction brought on by physical inactivity. Therefore this project addresses the concepts of microvascular function and microvascular fitness by using the latest technology to map blood flow routes in muscle under a number of relevant situations. Read moreRead less
Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equat ....Microdialysis for monitoring changes in microvascular flow patterns in muscle. Microdialysis is a technique for sampling interstitial fluid. Factors altering vascular delivery and removal of nutrients and hormones can affect muscle metabolism by altering exchange with the interstitium. This project focuses on microdialysis for assessing the impact of microvascular blood flow patterns on skeletal muscle metabolism and contractility. The aim is to develop and refine the technology, including equations, specifically for monitoring the nutritive fraction of blood flow in muscle by agents and factors relating to health and disease. This technique could be used for screening drugs in the treatment of diseases such as type 2 diabetes and related conditions.Read moreRead less
A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability ....A New Platform for Developing a Compound Against Herpes Simplex Virus. This project aims to further explore the research team’s recent fundamental discovery of a protein found naturally in an Australian abalone that inhibits viral entry by blocking three key viral glycoproteins. We would aim to utilise this knowledge towards development of a new class of therapeutics against Herpes simplex viruses (HSV) and their consequent infections. The new therapeutics could overcome the low bioavailability of current drugs and thus significantly shorten the recurrence period. Such new drugs may have broad applicability.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100018
Funder
Australian Research Council
Funding Amount
$630,000.00
Summary
Purchase of a high resolution Nuclear Magnetic Resonance spectrometer with liquid chromatography module. A high resolution Nuclear Magnetic Resonance spectrometer and liquids separation module will support Tasmanian research of international significance across the biological and medical sciences, chemistry and Tasmanian industries including profiling studies in human health, plant biology, molecular basis of disease and complex mixture analysis.
ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas ....ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas of human health through the regeneration of damaged nerves (eg. in spinal injury) and development of artificial muscles; in renewable energy (plastic solar cells, lightweight batteries and electronic textiles) and in sustainable industries (recovery of precious metals and new corrosion protection technologies).Read moreRead less